Chemical Sciences
Dermot Brougham
B.Sc., Ph.D. (UCD)
Lecturer, Physical Chemistry
NMR spectroscopy applied to materials science
Our research is on NMR spectroscopy applied to studying dynamic processes in the solid and liquid state. Specifically we perform temperature- and magnetic field-dependent NMR measurements to study exchange and dynamic processes in interesting material and biological systems. Current projects include:
- Metabolic profiling (metabonomics) of cancer by NMR spectroscopy.
- Magnetic nanoparticles for medical imaging and drug delivery.
- NMR studies of electronic and ionic conduction in the solid state.
- Proton Transport in New Materials for Fuel Cells
- New Contrast Agents for Medical Imaging
- Membrane Dynamics
- Computational and Synthetic Organic Chemistry
a) Left; NMR spectrum of intact cancer cells, right classification of cells using NMR spectra
(b) Images of magnetic nanowires formed from single stranded DNA, (c) Nanocrystalline conducting polymers.
Recent Publications
- “Controlled growth of nanoparticle clusters through competitive stabilizer desorption.” Stolarczyk JK, Ghosh S, Brougham DF. Angewandte Chemie-Int. Ed, 2009, 48, 1, 175-178.
- "Linear assemblies of magnetic nanoparticles as MRI contrast agents", S. A. Corr, S. J. Byrne, R. Tekoriute, C. J. Meledandri, D. F. Brougham, M. Lynch, C. Kerskens, L. O' Dwyer and Y. K. Gun’ko, Journal of the American Chemical Society, 2008, 130(13), 4214-4215.
- "Non-aqueous magnetic nanoparticle suspensions with controlled particle size and nuclear magnetic resonance properties. C. J. Meledandri, J. K. Stolarczyk, S. Ghosh, D. F. Brougham. Langmuir, 2008, 24(24) 14159-14165.
- "A field-cycling NMR relaxometry study of dynamic processes in conducting polyaniline", E. Murray, D. Carty, P. Innis, G. Wallace and D. F. Brougham. J. Phys. Chem. C. 2008, 112(45) 17688-17693
- "Metabolomic studies of human lung carcinoma cell lines by in vitro 1H nuclear magnetic resonance of whole cells and cellular extracts". M. Gottschalk, G. Ivanova, D. M. Collins, A. Eustace, R. O’Connor and D. F. Brougham. NMR in Biomedicine, 2008, 29, 809-819.
