Chemical Sciences

Mirek Macka

mirek macka Mirek Macka
RNDr., Ph.D., MRACI, MRSC, C.Chem.
Marie Curie Excellence Grants Fellow



Name: Mirek Macka
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Analytical Chemistry

Analytical chemistry, separation science, capillary electrophoresis, chromatography, hybrid pressure-electro-driven methods, hyphenated methods, miniaturised analytical and chemical systems, microfluidics, Lab-on-chip, Light emitting diodes (LEDs) and diode lasers in chemistry

The research in our "Microfluidic analysis" (µ-FAn) research group investigates the theory, practice and applicability of modern miniaturised chemical analysis methods, especially electro-driven separation methods and hybrid pressure-electro-driven methods, and their key areas, including sample preconcentration and detection. Particular interest is in the areas of miniaturisation, microfluidic chips (lab-on-chip), utilisation of modern technologies in chemistry, and modelling.

Dr. Macka's personal research page

Areas of research as current or potential projects include:
  • 'Exotic' monoliths - novel monolithic stationary phases for chromatography with unusual properties, including 'smart' photochromic and other active/switching phases
  • Preconcentration and matrix removal methods for capillary electrophoresis/electrochromatography of biomolecules
  • Biochips with specific bioanalyte-targeted monolithic preconcentrators
  • Capillary electrophoresis/electrochromatography/capillary chromatography with LED- and laser diode-based detection
  • Engineering challenges in miniaturised chemical analysis
  • Smart high-tech-low-$ gadgets for chemistry
  • Computer modelling of electrophoresis and other micro- and nano-scale chemical processes
  • The µ-FAn research group collaborates with several other research groups in the recently established Separation Science Cluster (SSC).

    Positions are available in both µ-FAn and SSC.

    Recent Publications

    1. Breadmore M.C., Henderson R., Fakhari A.-R., Macka M., Haddad P.R., Separation of nile- blue – labelled fatty acids by CE with absorbance detection using a red light-emitting diode, Electrophoresis, 28(8), 1252-1258, 2007.
    2. Bones J., Macka M., Paull B., Evaluation of Monolithic and a Sub 2µm Particle Packed Columns for the Rapid Screening for Illicit Drugs – Application to the Determination of Drug Contamination on Irish Euro Banknotes, Analyst, 132, 208-217, 2007.
    3. Balding P., Boyce M. C., Breadmore M. C., Macka M., LED-compatible probes for indirect detection of anions in capillary electrophoresis, Electrophoresis, 28(19), 3453 3460, 2007.
    4. Nie F.-Q., Kent N., Macka M., Paull B., On-chip preconcentration using a miniaturized electroosmotic pump and silica monoliths, Lab on Chip, 7, 1597 1599, 2007
    5. Evenhuis C.J., Johns C., Yang W.C., Guijt R.M., Macka M., Marriott P.J., Haddad P.R., The Potential of Fluorinated Ethylenepropylene Copolymer as a CE Capillary Material, Electrophoresis, 28(19), 3477 3484, 2007.
    6. Jonathan Bones, Cepta Duffy, Mirek Macka, Brett Paull, Using Coupled Monolithic Rods for Ultra-High Peak Capacity LC-MS under Normal LC Operating Pressures, Analyst, 133(2), 180-183, 2008.
    7. Silvija Abele, Fu-Qiang Nie, František Foret, Brett Paull, Macka M., UV LED photopolymerised monoliths, Analyst, 132, 864 - 866, 2008. This brake-through work presents a new concept of photopolymerisations of monoliths using deep-UV LEDs. Chosen for promotion in the RSC supplement Chemical Technology;Featured on the cover of the issue and Selected as an Analyst Hot Article.