Chemical Sciences

Biographical Details:

BSc - 1989 York University Canada PhD - 1996 York University 1996-1997 Research Chemist Novopharm Lmt. Toronto Canada. 1997-1998 Lead Formulation Chemist Chemlan Chemicals Toronto/South Carolina 1998-2001 Research Associate DCU/NCSR 2001- Lecturer School of Chemical Sciences DCU

Research Interests:

Macrocyclic/Receptor Chemistry, Phthalocyanines, Medicinal Chemistry, Sensors, Photochemistry, Microflow synthesis, Photocatalysis

Selected Peer Reviewed Journals

• Alexander Yavorskyy, Oksana Shvydkiv, Carolin Limburg, Kieran Nolan, Yan M. C. Delauré, Michael Oelgemöller. 2012. Green Photooxygenations in a bubble column reactor. Green Chemistry, 14,, pp888-892.
• Anne J Morrissey; Cecilia Fenech; Luc Roc; Kieran Nolan; John Tobin. 2012. The potential for a suite of isotope and chemical markers to differentiate sources of nitrate contamination: A review. Water Research, 46,, pp2023-2041.
• Alexander Yavorskyy, Oksana Shvydkiv, Norbert Hoffmann, Kieran Nolan, Michael Oelgemoeller. 2012. Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis. Organic Letters, 14, 17, pp4342-4345.
• Oksana Shvydkiv, Carolin Limburg, Kieran Nolan and Michael Oelgemo¨ller. 2012. Synthesis of Juglone (5-Hydroxy-1,4-Naphthoquinone) in a Falling Film Microreactor J. Flow Chem. 2,, pp52-55.
• Sharon Murphy, Carla Saurel, Anne Morrissey, John Tobin, Michael Oelgemöller, Kieran Nolan. 2012. Photocatalytic activity of a porphyrin/TiO2 composite in the degradation of pharmaceuticals. Applied Catalysis B: Environmental, 119-120,, pp156-165.
• Keane, David; Basha, Shaik; Nolan, Kieran; Morrissey, Anne; Oelgemoeller, Michael; Tobin, John M. 2011. Photodegradation of famotidine by integrated photocatalytic adsorbent (IPCA) and kinetic study. Catalysis Letters, 141, 2, pp300-308.
• Shaik Basha, Colin Barr, David Keane, Anne Morrissey, Kieran Nolan, Michael Oelgemoller, John Tobin. 2011. On the adsorption/photodegradation of Amoxicillin in aqueous solutions by an integrated photocatalytic adsorbent (IPCA): Experimental studies and kinetics analysis. Photochemical And Photobiological Sciences, 10, , pp1014-1022.
• Ann-Marie Deegan , Mark Cullen , Michael Oelgemöller , Kieran Nolan , John Tobin & Anne Morrissey. 2011. A SPE-LC-MS/MS Method for the Detection of Low Concentrations of Pharmaceuticals in Industrial Waste Streams. Analytical Letters, 44,, pp2808-2820.
• Oksana Shvydkiv, Alexander Yavorskyy, Su Bee Tan, Kieran Nolan, Norbert Hoffmann, Ali Youssef and Michael Oelgem¨oller. 2011. Microphotochemistry: a reactor comparison study using the photosensitized addition of isopropanol to furanones as a model reaction. Photochemical And Photobiological Sciences, 10, , pp1399-1404.
• Oksana Shvydkiv, Kieran Nolan and Michael Oelgemöller. 2011. Microphotochemistry: 4,4'-Dimethoxybenzophenone mediated photodecarboxylation reactions involving phthalimides. Beilstein Journal Of Organic Chemistry, 7, , pp1055-1063.
• Anne Morrissey; A. M. Deegan; B. Shaik; K. Nolan; K. Urell; M. Oelgemöller; J. Tobin; A. Morrissey Ann Marie Deegan. 2011. Treatment options for wastewater from pharmaceutical companies: a review. 8, 3, pp649-666.
• Alexander Yavorskyy , Oksana Shvydkiv , Kieran Nolan , Norbert Hoffmann , Michael Oelgemöller. 2011. Photosensitized addition of isopropanol to furanones in a continuous-flow dual capillary microreactor. Tetrahedron Letters, 52, , pp278-280.
• Emma E Coyle, Kieran Joyce, Kieran Nolan, Michael Oelgemoeller. 2010. Green photochemistry: the use of microemulsions as green media in photooxygenation reactions. Green Chemistry, 12, , pp1544-1547.
• O.Shvydkiv, A.Yavorskyy, K.Nolan, A.Youssef, E.Riguet, N.Hoffmann, M.Oelgemöller. 2010. Photosensitized addition of isopropanol to furanones in a 365 nm UV-LED microchip. Photochemical And Photobiological Sciences, 9, 12, pp1601-1603.
• S.B.Tan, O.Shvydkiv, J.Fielder, F.Hatoum, K.Nolan, M. Oelgemöller. 2010. Photodecarboxylative Additions of á-Thioalkyl-Substituted Carboxylates to Alkyl Phenylglyoxylates. Synlett, , pp2240-2243.
• Shaik Basha, David Keane, Anne Morrissey, Kieran Nolan, Michael Oelgemöller,John Tobin. 2010. Studies on the Adsorption and Kinetics of Photodegradation of Pharmaceutical Compound, Indomethacin Using Novel Photocatalytic Adsorbents (IPCAs). Industrial & Engineering Chemistry Research, 49, , pp11302-11309.
• Oksana Shvydkiv,Sonia Gallagher, Kieran Nolan, and Michael Oelgemoller. 2010. From Conventional to Microphotochemistry: Photodecarboxylation Reactions Involving Phthalimides. Organic Letters, 12, , pp5170-5173.
• Nameer Alhashimy, Dermot Brougham, Joshua Howarth, Alan Farrell, Brid Quilty and Kieran Nolan. 2007. Homochiral Tripodal Imidazolium Receptors: Structural and Anion-Receptor Studies. Tetrahedron Letters, 48, , pp125-128.
• Shane O¿Malley, Benjamin Schazmann, Dermot Diamond and Kieran Nolan. 2007. Preparation and sensor evaluation of a Pacman phthalocyanine. Tetrahedron Letters, 48, , pp9003-9007.
• Shane O¿Malley, Nameer Alhashimy , John O¿Mahony, Aisling Kieran , Mary Pryce and Kieran Nolan,. 2007. The Selective Preparation of Partial Cone O-Aryl Calix[4]arene Ethers from 1,3-Dimethoxycalix[4]arene: A new Platform for the Preparation of Non-Aggregated Dyes. Tetrahedron Letters, 48, , pp681-684.
• Andrea Dallas, Henry Kuhtz, Alan Farrell, Brid Quilty, and Kieran Nolan, Tetrahedron Letters,. 2007. Versatile Reagents: Ferrocenyl Azolium Compounds as Auxiliary Ligands for the Heck Reaction and Highly Effective Antifungal Agents,. Tetrahedron Letters, 48, 6, pp1017-1021.
• Benjamin Schazmann, Shane O¿Malley, Kieran Nolan and Dermot Diamond. 2006. Development of a calix[4]arene sensor for soft metals based on nitrile functionality: Relating structural tuning to an Ion Selective Electrode response. Supramolecular Chemistry, 18, 6, pp515-522.
• John O¿Mahony, Alexandra Molinelli, Kieran Nolan, Malcolm R. Smyth and Boris Mizaikoff. 2006. Anatomy of a Successful Imprint: Analysing the Recognition Mechanisms of a Molecularly Imprinted Polymer for Quercitin. Biosensors & Bioelectronics, 21, 7, pp1383-1392.
• Alexandra Molinelli, John O¿Mahony, Kieran Nolan, Malcolm R. Smyth, Michael Jakusch and Boris Mizaikoff. 2005. 4) Analysing the Mechanisms of Selectivity in Biomimetic Self-Assemblies via IR and NMR Spectroscopy of Prepolymerisation Solutions and Molecular Dynamics Simulations. Analytical Chemistry,
• Alexandra Molinelli, Kieran Nolan, Malcolm R. Smyth and Boris Mizaikoff,. 2005. 3) Anatomy of a Successful Imprint: Analysing the Recognition Mechanisms of a Molecularly Imprinted Polymer for Quercitin. in press,
• Benjamin Schazmann, Gillian McMahon, Kieran Nolan and Dermot Diamond. 2005. 6) Identification and Recovery of an Assymetric Calix[4]arene Tetranitrile Derivative Using liquid Chromatography and mass Spectrometry. Supramolecular Chemistry, 17, 5, pp393-399.
• John O¿Mahony, Kieran Nolan, Malcolm Smyth and Boris Mizaikoff. 2005. 1) Molecularly imprinted polymers-potential and challenges in analytical chemistry. 534, 1, pp31-39.
• John O¿Mahony, A Molinelli, Kieran Nolan, Malcolm Smyth and Boris Mizaikoff. 2005. 2) Towards the rational development of molecularly imprinted polymers: H-1 NMR studies on hydrophobicity and ion-pair interactions as driving forces for selectivity. Biosensors & Bioelectronics, 20, 9, pp1884-1893.
• Gillian McMahon, Shane O�Malley, Kieran Nolan and Dermot Diamond. 2003. Important Calixarene Derivatives � their Synthesis and Applications. Arkivoc, Arkivoc 2003 (vii), , pp23-31.
• Lynch A, Eckhard K, McMahon G, Wall R, Kane P, Nolan K, Schuhmann W, Diamond D. 2002. Cation binding selectivity of partially substituted calix[4]arene esters. Electroanalysis, 14,, pp1397-1404.
• McMahon G, Wall R, Nolan K, Diamond D. 2002. Characterisation of the ester-substituted products of the reaction of p-t-butyl calix[4]arene and ethyl bromoacetate using LC-UV-MS and LC-DAD. Talanta, 57,, pp1119-1132.
• C. Lynam, K. Jennings, K. Nolan, P. Kane, MA. Mckervey, D. Diamond. 2002. Tuning and Enhancing Enantioselective Quenching of Calixarene Hosts by Chiral Guest Amines. Analytical Chemistry, 74,
• D. Diamond, K. Nolan. 2001. Calixarenes, Designer Ligands for Chemical Sensors. Analytical Chemistry, 73,, pp23A-*.
• S. O'Neill, S. Conway, J. Twellmeyer, O. Egan, K. Nolan, D. Diamond. 1999. Ion-Selective Optode Membranes using 9-(4-diethylamino-2-octadecanoatestyryl)-acridine acidochromic dye. 398,
• K. Nolan, C.C. Leznoff, M. Hu. 1997. Adjacent Substituted Phthalocyanines (Synlett). 5,, pp593-*.
• C. C. Leznoff, M. Hu, K. Nolan. 1996. The Synthesis of Phthalocyanines at Room Temperature. Chemical Communications, *,, pp1245-*.
• D.S.Terekhov, K. Nolan, C. R. McArthur, C.C. Leznoff. 1996. Synthesis of 2,3,9,10,16,17,23,24-Octaalkynylphthalocyanines and the effects of Concentration and Temperature on their 1H NMR Spectra. Journal Of Organic Chemistry, 61,, pp3034-3040.
• Z. Jin, K. Nolan, C. R. McArthur, A. B. P. Lever and C. C. Leznoff,. 1994. Synthesis, Electrochemical and Spectroelectrochemical Studies of Metal-Free 2,9,16,23-Tetraferrocenylphthalocyanine. Journal Of Organometallic Chemistry, 468,, pp205-*.

Selected Chapters

• F. Cadigan, K. Nolan and D.Diamond,. 2001. Sensor Applications of Calixarene Derivatives. Calixarenes 2001

Selected Non-peer Reviewed Journals

• K. Nolan and D. Diamond. 1999. Molecular Recognition and Chemical Sensors. Irish Scientist, 7, pp121-*.

• Stephen Carey and Kieran Nolan, The Synthesis of Novel Pyrogallol[4]arenes, IUPAC ICOS, - ,
• Pauline Griffin and Kieran Nolan, The Synthesis of Novel Pyrogallol[4]arenes, IUPAC ICOS-15, - , Japan
• Aisling Redmond, Ian Gray, Kieran Nolan, Susan McDonnell, Cytotoxicity of bioreductive drugs derived from 5-fluorouracil, In: Anticancer Research ed. , - , Belfast, 3610 - 3610
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• O. Shvydkiv, A. Yavorskyy, K. Nolan, M. Oelgemoeller, Micro-photochemistry - a New Resources-Efficient Synthesis Tool Approach, Green Chemistry in Ireland, 15-APR-10 - , Dublin, Ireland
• O. Shvydkiv, A. Yavorskyy, K. Nolan, M. Oelgemoeller, Photodecarboxylations of Phthalimides and Photooxygenations of alpha-Terpinene as Model Reactions in Microstructured Reactors, Central European Conference on Photochemistry ¿ CECP 2010, 07-FEB-10 - 09-FEB-10, Bad Hofgastein,Austria
• Emma E. Coyle, Kieran Joyce, Michael Oelgemöller and Kieran Nolan, ¿Green Photochemistry¿: dye-sensitised photooxygenation as a case study, Irish Graduate Student Symposium,, 17-JUN-09 - , Dublin Institute of Technology
• 1) Michael Oelgemöller, Sonia Gallagher, Su Bee Tan, Fei Chen, Kieran Nolan, Mirek Macka, Microphotochemistry -Photochemistry in Microstructured Reactors, AIChE Spring National Meeting, 26-APR-09 - 30-APR-09, Tampa, FL, USA,
• Butler J, Nolan K, McDonnell S, Hughes L, Evaluation of the cytotoxicity of a series of novel 5-Fluorouracil carbonate derivatives in normal and cancer breast cell lines, IRISH ASSOCIATION FOR CANCER RESEARCH, 05-MAR-09 - 06-MAR-09, Athlone
• Mark Cullen, Kieran Nolan,Anne Morrissey, Michael Oelgemöller,John Tobin, Modelling a production plant to predict pharmaceutical residues entering the environment, ENVIRON, 18-FEB-09 - 20-FEB-09, Waterford
• S.Murphy, K.Nolan, A.Morrissey, J.Tobin and M.Oelgemöller, Water Treatment with Light: Photochemical Degradation of Pharmaceuticals in the Environment, ENVIRON, 18-FEB-09 - 20-FEB-09, Waterford
• Deegan, A.M.1, Nolan, K.2, Oelgemöller, M.3, Morrissey, A.4, Tobin, T, A SPE-LC-MS/MS method for the detection of three active pharmaceutical ingredients in industrial waste waters and their removal using photocatalysis, ENVIRON, 18-FEB-09 - 20-FEB-09, Waterford
• Emma Coyle, Kieran Joyce, Elodie Haggiage, Kieran Nolan and Michael Oelgemöller, ¿Green Photochemistry¿ - the solar synthesis of quinonoid fine chemicals, ENVIRON, 18-FEB-09 - 20-FEB-09, Waterford
• Kieran Joyce, Emma Coyle, Celine Thienpont, Kieran Nolan and Michael Oelgemöller, Green Chemistry: From the laboratory to the roof tops, ENVIRON, 18-FEB-09 - 20-FEB-09, Waterford
• Irene Hughes, Kieran Nolan and Mary Pryce, Synthesis of Novel calix[4]arene porphynoids, In: Journal of Porphyrins and Phthalocyanines ed.International Conference on Porphyrins and Phthalocyanines, 02-JUL-06 - , Rome, 668 - 668
• Ide Ni Almhain, Shane O¿Malley and Kieran Nolan, Synthesis of calix[4]arene-phthalocyanine complexes, In: Journal of Porphyrins and Phthalocyanines ed.International Conference on Porphyrins and Phthalocyanines, 02-JUL-06 - 07-JUL-06, Rome, 797 - 797
• Shane O¿Malley and Kieran Nolan, Synthesis of constrained and cofacially arranged binuclear phthalocyanines on a calix[4]arene scafold, International Conference on Porphyrins and Phthalocyanines, 02-JUL-06 - , Rome, 804 - 804
• Shane O'Malley and Kieran Nolan, Synthesis of calix[4]arene phthalocyanines, ESOC, 04-JUL-05 - 10-JUL-04, Helsinki
• A Redmond, I Gray, K Nolan, S McDonnell, Cytotoxicity of bioreductive drugs derived from 5-fluorouracil, Anticancer Research, 01-SEP-04 - ,
• John O'Mahony, Alexandra Molinelli, Kieran Nolan, Malcolm Smyth, Boris Mizaikoff, Molecular imprinting technology: designing molecule-specific materials for analytical chemistry, In: American chemical society ed.55th Southeast Regional Meeting of the American Chemical Society, 16-NOV-03 - 19-NOV-03, Atalanta
• Molinelli, Alexandra; O'Mahony, John; Nolan, K.; Smyth, M.; Mizaikoff, Boris., Spectroscopic studies of pre-polymerization mixtures in molecular imprinting: towards a rational approach for optimized imprinting conditions., In: American chemical Society ed.55th Southeast Regional Meeting of the American Chemical Society, 16-NOV-03 - 19-NOV-03,
• J Yang, K Nolan, Solid-support synthesis of unsymmeritrically substituted phthalocyanines used in photodynamic therapy (PDT), Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• C Lynam, K Nolan, G McMahon, D Diamond, Tuning the wavelength of enantioselective quenching of a calixarene host by phenylalaninol, Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• I Gray, K Nolan, Designing a more selective anticancer prodrug, Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• S O'Malley, K Nolan, Synthesis of ionophoric phthalocyanine receptors, Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• JO Mahony, A Molinelli, K Nolan, MR Smyth, B Mizaikoff, Rational development of molecularly imprinted polymers: elucidating the nature of pre-polymerisation complexes via simple nmr experiments, Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• N Alhashimy, K Nolan, J Howarth, The synthesis and application of novelhomochiral tripodal azolium salts., Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal
• SJ Carey, K Nolan, The synthesis of novel pyrogallol calixarenes, Synthetic Receptors 2003, 15-OCT-03 - 17-OCT-03, Portugal