Chemical Sciences

Biographical Details:

2004- Lecturer, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland. Appointed 19/10/04. Start Date 01/11/04. 2000-2004 Post Doc with Prof. Peter Scammells, Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, Melbourne, Australia. 2000-2000 Post Doc with Dr. Peter Scammells, School of Chemical and Biological Sciences, Deakin University, Geelong, Victoria, Australia. 1998-2000 Post Doc with Prof. Karl Anker Jorgensen, Centre for Catalysis, Department of Chemistry, Aarhus University, Denmark. 1994-1998 PhD (Organic Chemistry) with Prof. Richard Whitby, Southampton University, England, Awarded 19/04/1999. 1990-1994 BSc(Hons) 2:1 Chemistry, Bath University, England, Awarded 27/06/94.

Research Interests:

Medicinal Chemistry, Macrocycles, Alkaloids, Asymmetic catalysis and Green Chemistry.

Selected Peer Reviewed Journals

• Kowalska, E.; Phopase, J.; and Gathergood, N.*. 2010. Synthesis, X-ray crystal studies and metal picrates extraction properties of benzocrown ether analogues .. Australian Journal Of Chemistry, 63,, pp1348-1357.
• Myles, L.; Gore, R.; Spulak, M.; Gathergood, N.* and Connon, S. J.*. 2010. Highly recyclable, imidazolium derived ionic liquids of low antimicrobial and antifungal toxicity: A new strategy for acid catalysis.. Green Chemistry, 12,, pp1157-1162.
• Deng, Y; Morrissey, S.; Gathergood, N.; Delort, A.-M.; Husson, P.; and Costa Gomes, M. F.*. 2010. The Presence of Functional Groups Key for Biodegradation in Ionic Liquids: Effect on Gas Solubility. ChemSusChem. Chemsuschem, 3, 3, pp377-385.
• Coleman, D. and Gathergood N.*. 2010. Biodegradation Studies of Ionic Liquids. Chemical Society Reviews, 39,, pp600-637.
• Procuranti, B.; Myles, L.; Gathergood, N.; Connon, S. J. 2009. Pyridinium Ion Catalysis of Carbonyl Protection Reactions. Synthesis. Synthesis, 23,, pp4082-4086.
• Morrissey, S.; Beadham, I.; Gathergood, N.*. 2009. Selective hydrogenation of trans-cinnamaldehyde and hydrogenolysis-free hydrogenation of benzyl cinnamate in imidazolium ILs. Green Chemistry, 11, , pp466-474.
• Morrissey, S.; Pegot, B.; Coleman, D.; Garcia, M. T.; Ferguson, D.; Quilty, B.; Gathergood, N.*. 2009. Biodegradable, non-bactericidal oxygen-functionalised imidazolium esters: A step towards `greener¿ ionic liquids. Green Chemistry, 11, , pp475-483.
• Bouquillon, S.; Courrant, T.; Dean, D.; Gathergood, N.*, Morrissey, S.; Pegot, P.; Scammells, P. J.*. 2007. Biodegradable Ionic Liquids: Selected Synthetic Applications. Australian Journal Of Chemistry, 60, 11, pp843-847.
• Gathergood, N.; Scammells, P. J.; Garcia, M. T. 2006. Biodegradable ionic liquids Part III: The first readily biodegradable ionic liquid. Green Chemistry, 8, 2, pp156-160.
• N. Anastos, N.W. Barnett, S.W. Lewis, N. Gathergood, P.J. Scammells, and D.N. Sims. 2005. Synthesis and Detection of Psilocin and Psilocybin using Flow Injection Analysis with Chemiluminescence Detection. Talanta, 67, 2, pp354-359.
• White, B.; Tarun, M. C.; Gathergood, N.; Rusling, J. F.; Smyth, M. R. 2005. Oxidised guanidinohydantoin (Ghox) and spiroiminodihydantoin (Sp) are major products of iron- and copper-mediated 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2¿-deoxyguanosine oxidation. Molecular Biosystems, 1, 5/6, pp373-381.
• M. Teresa Garcia, Nicholas Gathergood and Peter J. Scammells. 2005. COVER ARTICLE/ILLUSTRATION. Biodegradable Ionic liquids: Part II. Counter-ion effect and toxicology. Green Chemistry, 7(1), , pp9-14.
• Gathergood, N.*; Poulsen, T. B.; Juhl, K.; Thordrup, K; Jørgensen K. A.*. 2004. Direct catalytic asymmetric aldol reactions of pyruvates: scope and mechanism details. Organic And Biomolecular Chemistry, 2(7), , pp1077-1085.
• Gathergood, N.; Garcia, M. T.; Scammells, P. J. 2004. Biodegradable Ionic Liquids Part I: Concept, Preliminary Targets and Evaluation. Green Chemistry, 3, , pp166-175.
• Hemeon, I.; Barnett N. W.; Gathergood, N.; Scammells, P. J.; Singer, R. D. 2004. Manganese Dioxide Allylic and Benzylic Oxidation Reactions in Ionic Liquids. Australian Journal Of Chemistry, 2, , pp125-130.
• Gathergood, N.*; Fallon, G. D.; Scammells, P. J. 2003. 7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-6-yl naphthalene-1-carboxylate. Acta Crystallographica Section E, E59, , ppo1918-o1919.
• Gathergood, N.*; Fallon, G. D.; Scammells, P. J. 2003. Inter- and intramolecular C-H�pi interactions in morphine bis(1-naphthoate). Acta Crystallographica Section C, C59, , ppo485-o487.
• M. Marigo, A. Kjaersgaard, K. Juhl, N. Gathergood, K. A. Jørgensen. 2003. Direct Catalytic Asymmetric Manich Reactions of Malonates and beta-keto esters. Chemistry - A European Journal, 9(10), , pp2359-2367.
• N. Gathergood, P. Scammells. 2003. Preparation of the 4-hydroxytryptamine scaffold via a palladium catalysed cyclization: synthesis of psilocin. Organic Letters, 5, , pp921-923.
• N. Gathergood*. 2002. Asymmetric Organocatalysis: proline an essential amino-acid?. Australian Journal Of Chemistry, 55, , pp615-615.
• N. Gathergood, P. Scammells. 2002. Design and preparation of room temperature ionic liquids containing biodegradable side-chains. Australian Journal Of Chemistry, 55, , pp557-560.
• Y. Wan, K. Ding, L. Dai, A. Ishii, V. A. Soloshonok, K. Mikami, N. Gathergood, W. Zhuang, K. B. Jensen, J. Thorhauge, R. G. Hazell, K. A. Jørgensen. 2001. Enantioselective Friedel-Crafts reaction: from stoichiometric to catalytic. Chemtracts, 14(11),, pp610-615.
• K. Juhl, N. Gathergood, K. A. Jørgensen. 2001. COVER ARTICLE/ILLUSTRATION Catalytic asymmetric direct Mannich reactions of carbonyl compounds with alpha-imino esters. Angewandte Chemie-international Edition In English, 40(16), , pp2995-2997.
• N. Gathergood, K. R. Knudsen, K. A. Jørgensen. 2001. Enantioselective Synthesis of Optically Active Carbocyclic Sugars. Journal Of Organic Chemistry, 66(3), , pp1014-1017.
• W. Zhuang, N. Gathergood, R. G. Hazell, K. A. Jørgensen. 2001. Catalytic, Highly Enantioselective Friedel-Crafts Reactions of Aromatic and Heteroaromatic Compounds to Trifluoropyruvate. A Simple Approach for the Formation of Optically Active Aromatic and Heteroaromatic Hydroxy Trifluoromethyl Esters. Journal Of Organic Chemistry, 66(3), , pp1009-1013.
• N. Gathergood, W. Zhuang, K. A. Jørgensen. 2000. Catalytic Enantioselective Friedel-Crafts Reactions of Aromatic Compounds with Glyoxylate: A Simple Procedure for the Synthesis of Optically Active Aromatic Mandelic Acid Esters. Journal Of The American Chemical Society, 120(50), , pp12517-12522.
• K. Juhl, N. Gathergood, K. A. Jørgensen. 2000. Catalytic asymmetric homo-aldol reaction of pyruvate-a chiral Lewis acid catalyst that mimics aldolase enzymes. Chemical Communications, 22, , pp2211-2212.
• S. Saaby, X. Fang, N. Gathergood, K. A. Jørgensen. 2000. Formation of optically active aromatic alpha-amino acids by catalytic enantioselective addition of imines to aromatic compounds. Angewandte Chemie-international Edition In English, 39(22), , pp4114-4116.
• N. Gathergood, K. A. Jørgensen. 1999. Synthesis of optically active bicyclic lactone building blocks using catalytic enantioselective glyoxylate-ene reaction. Chemical Communications, 18, , pp1869-1870.
• X. Fang, M. Johannsen, S. Yao, N. Gathergood, R. G. Hazell, K. A. Jørgensen. 1999. Catalytic Approach for the Formation of Optically Active Allyl alpha-Amino Acids by Addition of Allylic Metal Compounds to alpha-Imino Esters. Journal Of Organic Chemistry, 64(13), , pp4844-4849.

Selected Chapters

• Dr Nick Gathergood. .
• Mukund Ghavre, Saibh Morrissey and Nicholas Gathergood*. 2011. Hydrogenation in Ionic Liquids. Ionic Liquids: Applications and Perspectives , pp331-392.
• Haibo Xie, Thomas Hayes, Nick Gathergood*. 2009. Catalysis of Reactions by Amino Acids. . Amino Acids, Peptides and Proteins in Organic Chemistry: Volume 1 - Origins and Synthesis of Amino Acids,, pp283-338.

• , , , - ,
• , , , - ,
• Nick Gathergood, Biodegradable ionic liquids, SETAC, 11-NOV-07 - 16-NOV-07, Milwaukee
• Ewa Kowalska, Nick Gathergood, Pharmaceuticals: Chiral building blocks for asymmetric catalysis, Irish Postgraduate Sympossium, 13-JUN-07 - 15-JUN-07, DCU
• Nick Gathergood, Biodegradable Ionic Liquids: Selected Synthetic Applications, Biodegradation and Toxicity of ionic liquids, 05-MAY-07 - 09-MAY-07, Berlin, Germany
• nick gathergood, Chiral Macrocycles, 25th Anniversary Gregynog Organic Synthesis Meeting, 26-SEP-05 - 28-SEP-05, Gregynog
• Nicholas Gathergood, DESIGN AND PREPARATION OF BIODEGRADABLE ROOM TEMPERATURE IONIC LIQUIDS, 19th Royal Australian Chemical Institute Organic Conference, 06-JUL-03 - 11-JUL-03, Lorne, Victoria, Australia