Biotechnology
Dr Christine Loscher
| Name: | Dr Christine Loscher |
|---|---|
| Phone Number | 5244 |
| Room: | X218 |
| E-Mail Address: | |
| Work Area: | Academic Staff |
Dr Christine Loscher
Research Interests:
Immunomodulation, Autoimmunity, Inflammatory bowel disease, Nutrition, GI infections
Selected Peer Reviewed Journals
- Dr Christine Loscher. .
- Moloney F., Toomey S., Noone E., Nugent A., Allan B., Loscher CE and Roche HM. 2007. Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue. Diabetes, 56, 3, pp574-582.
- Armstrong, M.E., Lavelle, E.C., Loscher, C.E., Lynch, M.A. and Mills, K.H. 2005. Pro-inflammatory responses in the murine brain following intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in nasal vaccines. Journal Of Infectious Disease, 192, 9, pp1628-1633.
- De Roos B, Rucklidge G, Reid M, Pickard K, Navarro MA, Arbones-Mainar JM, Guzman-Garcia MA, Osada J., Browne J., Loscher CE. and Roche HM. 2005. Divergent mechanisms of cis9, trans11- and trans10, cis12-conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach. Faseb Journal, 19, 12, pp1746-1758.
- Kelly, Á., Vereker, E., Nolan Y, Brady, M., Barry, C., Loscher, C.E., Mills, K.H and Lynch, M.A. 2003. Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1beta on long-term potentiation in rat dentate gyrus. Journal Of Biological Chemistry, 278, 21, pp19453-19562.
- Loscher, C.E., Mills, K.H. and Lynch, M.A. 2003. Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type ¿¹ receptor. Journal Of Neuroimmunology, 137, 1-2, pp117-124.
- 6) Loscher, C.E.,* Armstrong, M.E.,* Lynch, M.A. and Mills, K.H. 2003. IL-1beta dependent neurological side effects of the whole cell pertussis vaccine: a role for IL-1-associated signaling components in vaccine reactogenicity. Journal Of Neuroimmunology, 136, 1-2, pp25-33.
- Donnelly S., Loscher C.E., Lynch M.A. and Mills K.H. 2001. Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1beta in a new murine model for analysis of neuronal side effects of vaccination. Infection And Immunity, 69, 7, pp4217-4223.
- Loscher C.E., Donnelly S., Mills K.H. and Lynch, M.A. 2000. Interleukin-1-beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine. Journal Of Neuroimmunology, 111, 1-2, pp68-76.
- Loscher C.E., Donnelly S., Lynch M.A. and Mills K.H. 2000. Induction of inflammatory cytokines in the brain following respiratory infection with Bordetella pertussis. Journal Of Neuroimmunology, 102, 2, pp172-181.
- Donnelly S., Loscher C.E., Mills K.H. and Lynch, M.A. 1999. Glycerol-induced seizure: involvement of IL-1beta and glutamate. Neuroreport, 10, 9, pp1821-1825.
- Loscher C.E., Donnelly S., McBennet S., Lynch M.A. and Mills K.H. 1998. Proinflammatory cytokines in the adverse systemic and neurologic effects associated with parenteral injection of a whole cell pertussis vaccine. Annals Of The New York Academy Of Science, 856, , pp274-277.
- Kelly, J.A., Loscher, C.E., Gallagher, S. and O¿Connor, B. 1997. Degradation of pyroglutamyl-phenylalanyl-proline amide by a pyroglutamyl aminopeptidase purified from membrane fractions of bovine brain. Biochemical Society Transactions, 1, , pp114-.
