NICB

Biographical Details:

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Selected Peer Reviewed Journals

• Brougham DF, Ivanovo G, Gottschalk M, Collins DM, Eustace AJ, O'Connor R, Havel J. 2011. Artificial neural networks for classification in metabolomic studies of whole cells using 1H nuclear magnetic resonance. Journal Of Biomedicine And Biotechnology, 2011,
• Eustace AJ, Dowling P, Henry M, Doolan P, Meleady P, Clynes M, Crown J, O'Donovan N.. 2011. 2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines.. Journal Of Proteomics, 1, 74(4), pp490-501.
• N. Walsh, S. Kennedy, A.M. Larkin, D .Tryfonopoulos, A.J. Eustace, T. Mahgoub, C. Conway, I. Oglesby, D. Collins, J. Ballot, W.S. Ooi, G. Gullo, M. Clynes, J. Crown, L. O¿Driscoll. 2010. Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis. British Journal Of Cancer, 30, 102, pp1157-1162.
• G. I. Ivanova, E. J. Cabrita1, R. O´Connor, A. J. Eustace, D. F. Brougham. 2008. Application of diffusion-ordered spectroscopy for the analysis of cancer related biological samples. Bulgarian Chemical Communications, 40, 4, pp464-468.
• M.Gottschalk,G.Ivanova,D.Collins, A.J.Eustace, R.O'Connor, D.Brougham. 2008. Metabolomic studies of human lung carcinoma cell lines using in vitro (1) H NMR of whole cells and cellular extracts. Nmr In Biomedicine, 21, 8, pp809-819.
• A.J. Eustace, J. Crown, M. Clynes, N. O'Donovan. 2008. Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines. Journal Of Translational Medicine, 29, 6
• S.A Glynn, N. O'Donovan, D. O'Sullivan, A.J. Eustace and M. Clynes. 2008. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. Bmc Cancer, 16, 8

Reviews

• A.J.Eustace, T. Mahgoub, D. Tryfonopolous, N. O¿Donovan, J. Crown. 2010. Prospects for non-immunological molecular therapeutics in melanoma. Journal - Balkan Union Of Oncology, 15, pp9-18.

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• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Effects of Src kinase inhibition by dasatinib in melanoma cell lines., Irish Association for Cancer Research. Annual Meeting 2008, - , Newcastle Co. Down
• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Effects of Src kinase inhibition by dasatinib in melanoma cell lines., Targeted Anticancer Therapies conference, - , Washington U.S.A.
• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Preclinical evaluation of dasatinib in melanoma cell lines., European Association of Cancer Researchers Annual General Meeting 2009, - , Lyon France
• Eustace A.J., O¿Donovan N., Crown J., Clynes M, Biomarkers for dasatinib treatment in melanoma. IACR conference, Irish Association for Cancer Research Annual meeting 2009, - , Athlone Ireland
• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Expression of ABC transporters in melanoma cell lines., Global mRNA and Protein Expression Analysis, 2006, DCU, - , Dublin City University
• Eustace A.J., Susan Kennedy, Ann-Marie Larkin, Thamir Mahgoub, Dimitrios Tryfanopoulos, Lorraine O¿Driscoll, Martin Clynes, John Crown, Norma O¿Donovan., Predictive biomarkers for dasatinib in melanoma, The Biochemical Society Independent Meeting. 2010, - , Belfast
• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Preclinical evaluation of dasatinib and sorafenib in melanoma cell lines., All-Ireland Clinical Oncology Research Group Melanoma Workshop 2010, - , Herbert Park Hotel Dublin 4
• Eustace A.J., O¿Donovan N., Crown J., Clynes M., Preclinical evaluation of dasatinib in melanoma cell lines., DCU Biotechnology Research Day 2010, - , Dublin City University
• Eustace AJ, Mahgoub T, Kennedy S, Crown J, Larkin A, Tryfonopoulos D, O'Driscoll L, Clynes M, O'Donovan N., Targeting SRC kinase (SRC) in melanoma cells, American Society of Clinical Oncologists Annual General meeting 2010, - , Chicago USA
• Mahgoub T, Eustace AJ, Collins DM, Clynes M, Crown J, O¿Donovan N, Cyclin dependent kinase 4 as a therapeutic target for metastatic melanoma., European Society of medical oncologists Annual general meeting 2010, - ,
• Eustace AJ, Browne BC, McDermott M, Gallagher C, Watson W, Crown J, O'Donovan N., Acquired Sensitivity to TRAIL Mediated Apoptosis in Lapatinib Resistant SKBR3 Cells , San Antonio Breast Cancer Symposium 2011, 03-DEC-11 - 06-DEC-11, San Antonio
• B. Browne, J. Crown, A. J. Eustace, S. Kennedy, N. O'Brien, A. Larkin, J. Ballot, T. Mahgoub, Z. Qadir, F. Sclafani, S. F. Madden, M. J. Kennedy, M. J. Duffy and N. O'Donovan, IGF1R and phosphorylated IGF1R in HER2-positive breast cancer., ASCO 2011, 03-JUN-11 - 06-JUN-11, Chicago
• Alex J. Eustace (1), John Crown (1, 2),Anne-Marie Larkin (1), Thamir Mahgoub (1, 2), Dimitrios Tryfonopoulos (1, 2), Lorraine O¿Driscoll (3), Martin Clynes (1), Susan Kennedy (2), Norma O¿Donovan (1), Identification of predictive biomarkers (BM) for dasatinib (D) treatment (Rx) of metastatic malignant melanoma (M), ASCO 2011, 02-JUN-11 - 06-JUN-11, Chicago
• Eustace AJ, Dowling P, Henry M, Doolan P, Meleady P, Clynes M, Crown J, O'Donovan N. , 2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines. , Irish Association for Cancer Research, 03-MAR-11 - 05-MAR-11, Cork
• Eustace A.J., Stafford P., Clynes M., Crown J., O¿Donovan N., Dasatinib overcomes acquired temozolomide resistance in metastatic melanoma cell lines., Irish Association of Cancer Research, 02-MAR-11 - 05-MAR-11, Cork