Biotechnology

Research Interests:

Cellular & Molecular Nutrition; Polyunsaturated fatty acids and Cell Biology; Conjugated linoleic acid isomers and Cancer; Conjugated linoleic acid and dairy functional foods; Hepatocytes and xenobiotic metabolism;Biological effects of Cholesterol Oxidation Products.

Selected Peer Reviewed Journals

• ANNA M KUCHTA AM , KELLY PM, Stanton C , Devery R. 2012. Milk fat globule membrane ¿ a source of polar lipids for colon health?. International Journal Of Dairy Technology,
• Dr Rosaleen A Devery. 2012. .
• Hennessy AA, Barrett E, Ross RO, Fitzgerald GF, Devery R and Stanton C. 2012. The Production of Conjugated α- Linolenic, γ-Linolenic and Stearidonic Acids by Strains of Bifidobacteria and Propionibacteria. Lipids,
• Hennessy AA, Ross, RP, Devery, R ; Stanton, C. 2011. The Health Promoting Properties of the Conjugated Isomers of alpha-Linolenic Acid. Lipids, 46, 2, pp105-119.
• Coakley M, Banni S, Johnson MC, Mills S , Devery R, Fitzgerald GF, Ross RP and Stanton C. 2009. Inhibitory effect of conjugated alpha linolenic acid from bifidobacteria of intestinal origin on SW480 cancer cells. Lipids, 44, 3, pp249-256.
• Hennessy AA, Ross RP, Devery R, Stanton C. 2009. Optimisation of a reconstituted skim milk based medium for enhanced CLA production by bifidobacteria. J Applied Microbiology. 106, 4, pp1315-1327.
• Coakley M, Johnson MC, McGrath E, Rahman S, Ross P, Fitzgerald GF, Devery R and Stanton C (2006). 2006. Intestinal bifidobacteria that produce trans-9, trans-11 CLA: a fatty acid with anti-proliferative activity against human colon SW480 and HT-29 cancer cells. Nutrition And Cancer, 56, 1, pp95-102.
• Coen P, Cummins P, Birney Y, Devery R, Cahill P. 2004. Modulation of Nitric Oxide and 6-keto-Prostaglandin F1alpha Production in Bovine Aortic Endothelial Cells by Conjugated Linoleic Acid. Endothelium, 11, 3-4, pp211-220.
• Rosberg-Cody E, Ross RP, Hussey S, Ryan CA, Murphy BP, Fitzgerald GF, Devery R, Stanton C. 2004. Mining the microbiota of the neonatal gastrointestinal tract for conjugated linoleic acid-producing bifidobacteria. Applied And Environmental Microbiology, 8, , pp4635-8-4641.
• Miller A., Stanton, C.. Murphy J and Devery, R. 2003. Conjugated linoleic acid-enriched milk fat inhibits growth and modulates CLA-responsive biomarkers in MCF-7 and SW480 human cancer cell line. British Journal Of Nutrition, 90, , pp877-885.
• Miller A., McGrath E., Stanton, C. and Devery, R. 2003. Trans Vaccenic acid is converted to conjugated linoleic acid (c9, t11-CLA) in MCF-7 and SW480 Cancer Cells. Lipids, 38,, pp623-632.
• Coakley M, Ross RP, Nordgren M, Fitzgerald G, Devery R, Stanton C. Journal of Applied Microbiology. 2003. Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. 94, 1, pp138-145.
• Miller A., Stanton, C. and Devery, R. 2002. Cis 9,trans 11-and trans10, cis 12- Conjugated Linoleic Acid Isomers Induce Apoptosis in Cultured SW480 Cells. Anticancer Research, 22,, pp3879-3888.
• Stanton, C., M. Coakley, JJ Murphy, GF Fitzgerald, R Devery, RP Ross. in 'Sciences des Aliments' 22: 439-447. 2002. Development of Dairy-Based Functional Foods. 22,, pp439-447.
• Miller A, Stanton C and Devery R. 2001. Modulation of arachidonic acid distribution by conjugated linoleic acid Isomers and linoleic Acid in MCF-7 and SW480 Cancer Cells. Lipids, 36,, pp1161-1168.
• Devery R, Miller A, Stanton C. 2001. Conjugated linoleic acid and oxidative behaviour in cancer cells. Biochemical Society Transactions, 29,, pp341-344.
• O'Shea, M, Devery, R., Lawless, F., Murphy, J and Stanton, C. 2000. Milk fat conjugated linoleic acid (CLA) inhibits growth of human mammary MCF-7 cancer cells. Anticancer Research, 20,, pp3591-3602.
• O'Shea, M., Devery, R., Lawless, F., Keogh, K and Stanton, C. 2000. Enrichment of the conjugated linoleic acid content of bovine milk fat by dry fractionation. International Dairy Journal, 10,, pp289-294.
• Cantwell, H, Devery, R, O'Shea, M, and Stanton C 34: 833-839. 1999. The effect of conjugated linoleic acid on the antioxidant enzyme defense system in rat hepatocytes. Lipids, 34,, pp833-839.
• Cantwell, H. and Devery, R. 1999. The response of the antioxidant defense system in rat hepatocytes is modified by Covi-ox. Cell Biology And Toxicology, 14,, pp401-409.
• Lawless, F, Stanton, C, L'Escop, P, Devery, R, Dillon, P, Murphy, JJ. 1999. Influence of breed on bovine milk cis-9, trans-11-conjugated linoleic acid content. Livestock Production Science, 62,, pp43-49.
• McCluskey, S., Hall, H., Stanton, C. and Devery, R. 1999. a-Tocopherol inhibits oxidative stress induced by cholestanetriol and 25-hydroxycholesterol in porcine ovarian granulosa cells. Molecular And Cellular Biochemistry, 194,, pp217-225.
• O'Shea, M, Stanton, C and Devery R. 1999. Antioxidant enzyme defence responses of human MCF-7 and Sw480 Cancer cells to conjugated linoleic acid. Anticancer Research, 19,, pp1953-1959.
• Lawless F, Murphy JJ, Harrington D, Devery R, Stanton C. 1998. Elevation of conjugated cis-9,trans-11-octadecadienoic acid in bovine milk because of dietary supplementation. Journal Of Dairy Science, 81,, pp3259-3267.
• Teehan CM Kelly PM Devery R O'Toole A. 1997. Evaluation of test conditions during the measurement of coffee stability of instant whole milk powder. International Journal Of Dairy Technology, 50,, pp113-121.
• Stanton C Lawless F Kjellmer G Harrington D Devery R Connolly JF Murphy J. 1997. Dietary influences on bovine milk cis-9 trans-11-conjugated linoleic acid content. Journal Of Food Science, 62,, pp1083-1086.
• McCluskey S Connolly JF Devery R OBrien B Kelly J Harrington D Stanton C. 1997. Lipid and cholesterol oxidation in whole milk powder during processing and storage. Journal Of Food Science, 62,, pp331-337.
• DOWLING L DEVERY R. 1995. USE OF HPLC FOR THE DETERMINATION OF SERUM 7-ALPHA- HYDROXYCHOLESTEROL IN CHOLESTYRAMINE-TREATED RATS. Biochemical Society Transactions, 23,, ppS362-S362.
• DOYLE V DEVERY R. 1994. A DIRECT 2-SITE PEROXIDASE-BASED ENZYME-LINKED-IMMUNOSORBENT- ASSAY FOR PROINSULIN. Journal Of Pharmaceutical And Biomedical Analysis, 12,, pp1079-1082.
• MCCLUSKEY S DEVERY R. 1993. VALIDATION OF CHROMATOGRAPHIC ANALYSIS OF CHOLESTEROL OXIDES IN DRIED FOODS. Trends In Food Science & Technology, 4,, pp175-178.
• DOYLE V DEVERY R. 1991. A BIOASSAY TECHNIQUE FOR PLASMA PROINSULIN MEASUREMENT. Biochemical Society Transactions, 19,, ppS55-S55.
• DOYLE V DEVERY R. 1990. A NOVEL-APPROACH TO MEASURE THE BIOLOGICAL-ACTIVITY OF HUMAN PROINSULIN. Biochemical Society Transactions, 18,, pp914-915.
• QUINN J DEVERY R. 1990. STUDY ON THE EFFECT OF ADRENERGIC AGENTS ON BILE-ACID SYNTHESIS INVITRO. Biochemical Society Transactions, 18,, pp913-914.

Selected Chapters

• Dr Rosaleen A Devery. .
• Devery R. 2007. Development of dairy based functional foods enriched in conjugated linoleic acid with special reference to rumenic acid. Functional dairy products Volume 2, pp443-495.
• Devery R. 2004. Um Caso de estudo sobre propriedade intelectuel em biotechnologie .[ Case study on intellectual property rights in biotechnology]. BIOÉTICA PARA AS CIÊNCIAS NATURAIS", Conferências e casos de estudo do FLAD-NSF International Bioethics Institute, Curso Internacional de Bioética. [Bioethics for the Natural Sciences", conferences and case studies from the FLAD/NSF International Bioethics Institute]., pp371-374.
• Devery R. 2003. Role of conjugated linoleic acid (CLA) in dairy fats for human health. Oils and Fats Volume 3, pp187-210.
• Devery R. 2003. Animal feeding strategies for conjugated linoleic acid enrichment of milk. . Advances in Conjugated linoleic acid Research Vol 2., pp123-145.
• Devery R. 2002. Formation and Content of Cholesterol Oxidation Products in Milk and Dairy Products. Cholesterol and Phytosterol Oxidation Products: Analysis, Occurrence, and Biological Effects.

Reviews

• O'Shea, M., Lawless, F., Stanton, C. and Devery, R. 1998. Review: Conjugated linoleic acid in bovine milk fat: a food-based approach to cancer chemoprevention. Trends In Food Science & Technology, 9, pp192-196.

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• Kuchta A, Kelly P, Murray B, Stanton C and Devery R, Downregulation of Akt and ERK by a polar lipid-enriched retentate fraction of buttermilk was associated with caspase-independent cell death in the SW480 colon cancer cell line., Abstract for poster presentation for Keystone Symposia on Molecular and Cellular Biology 'Lipid Biology and Lioptoxicity', 15-MAY-11 - 20-MAY-11, INEC Killarney, 74 - 74
• Kuchta A, Devery R, Stanton C, Kelly P., Anti-proliferative activity of buttermilk causes membrane permeabilization and apoptosis in SW480 colon cancer cells. , Molecules to Medicine, 16-JUN-10 - 16-JUN-10, UCC, Cork.
• Kuchta A , Devery R , Murray B , Stanton C ,Kelly P, In vitro studies of antiproliferative activity of buttermilk fractions obtained by cross flow microfiltration. , 101st AOCS Annual Meeting & Expo, , 16-MAY-10 - 19-MAY-10, Phoenix, USA.
• Kuchta A, Devery R, Murray B, Stanton C ,Kelly P., Buttermilk samples produced in pilot plant scale selectively inhibit growth of SW480 and HT-29 human colon cancer cell lines and HepG2 human hepatocellular liver cancer cell line by induction of apoptosis. , USA/Ireland Functional Food Conference, Poster presentation: , 09-MAR-10 - 11-MAR-10, Cork, Ireland.
• Kuchta A ,Devery R, Murray B, Stanton C ,Kelly P ., Effect of buttermilk samples produced under different conditions on growth of SW480 human colon cancer cells and FHC human colon normal mucosa cells. , Biochemical Society Annual Meeting, , 12-NOV-09 - 12-NOV-09, UCD, Dublin
• Kuchta A , Devery R , Murray B, Stanton C and Kelly P. , Effect of buttermilk samples produced under different conditions on growth of SW480 human colon cancer cells and FHC human colon normal mucosa cells. , 11.11.2009. Walsh Fellow Seminar, . , 11-NOV-09 - 11-NOV-09, RDS, Dublin
• Kuchta A, Devery R, Murray B,Stanton C ,Kelly P, Effect of sweet and fermented buttermilk samples on growth of SW480 human colon cancer cells and FHC human colon normal mucosa cells., EuroFed Lipid Congress,, 18-OCT-09 - 21-OCT-09, Graz, Austria.
• Kuchta A,DeveryR Murray B, Stanton C , Kelly P, Effect of Ceramide and Sphingosine on growth of SW480 Human Colon Cancer Cell Line , FEBS Advanced course ¿Lipid signaling pathways: from cell biology to novel drug targets", 22-28 June 2007, Ortona, Italy,, 22-JUN-07 - 28-JUN-07, Ortona Italy
• Miller A., Devery R., and Stanton C, Effect of conjugated linoleic acid isomers on arachidonic acid metabolism in colon cancer cells., 17th International Congress of Nutrition , 27-AUG-01 - 31-AUG-01, Vienna, Austria
• Miller A., McGrath, E., Devery, R. and Stanton, C, Effects of vaccenic acid and CLA on growth of human colon cancer cells., 1st International Conference on Conjugated linoleic acid, 10-JUN-01 - 13-JUN-01, Alesund, Norway
• Devery, R., Miller, A., and Stanton, C., A review of the effect of conjugated linoleic acid on apoptosis in cancer., IIAR Conference on Apoptosis, 25-MAY-01 - 28-MAY-01, International Institute for Anticancer research, Athens, Greece
• O'Shea M., Devery R., Lawless F, Murphy J & Stanton C., Fatty acid composition of MCF-7 breast cancer cells following exposure to milkfat enriched in conjugated linoleic acid (CLA)., Nutrition 2000 International Dairy Foundation Meeting , 29-MAY-00 - 31-MAY-00, Berkely Court Hotel, Dublin
• Miller, A, O'Shea S, Stanton C and Devery, R., Differential effects of Conjugated linoleic acid and Linoleic acid on cell proliferation and PGE2 synthesis in the MCF-7 breast cancer cell line, 40th International Conference on the Biochemistry of Lipids, 14-SEP-99 - 17-SEP-99, University of Burgundy, Dijon, France
• Cantwell H, O'Shea M., Stanton, C and Devery, R, Comparative effects of CLA and tocopherols on the antioxidant defense system of rat hepatocytes and cancer cells., Nutrition Meeting of European Concerted Action on CLA, 14-JAN-99 - 15-JAN-99, INRA, Dijon, France
• Cantwell H, O'Shea M., Stanton, C and Devery, R, The effects of conjugated linoleic acid (CLA) on the antioxidant enzyme defense system of rat hepatocytes., 2nd Meeting of the European Section of AOCS, 01-OCT-98 - 04-OCT-98, Cagliari, Italy
• Cantwell, H., Devery R., O'Shea, M. and Stanton, C., Differential effects of conjugated linoleic acid on antioxidant defense enzymes in normal liver cells and cancer cells, 2nd International Conference on Natural antioxidants and Anticarcinogens in Nutrition, Health and Disease , 24-JUN-98 - 27-JUN-98, Helsinki, Finland
• O'Shea, M.,Cantwell, H. Devery, R., Lawless, F and Stanton, C, An in vitro investigation of the effects of CLA on cells in culture., Functional Foods: Designer Foods for the Future , 30-SEP-97 - 02-OCT-97, Silver Springs Hotel, Cork
• Lawless, F., Connolly, B., Devery, R., Murphy, J. and Stanton, C, Dietary and seasonal effects on bovine milkfat conjugated linoleic acid (CLA) contents., 16th International Congress of Nutrition,, 27-JUL-97 - 01-AUG-97, Montreal, Canada