Chemical Sciences

Research Interests:

Organic Synthesis Heterocyclic Chemistry NMR spectroscopy

Selected Peer Reviewed Journals

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• T. Duff, J. P. James and H. Müller-Bunz.. 2006. Synthesis and X-ray Crystal structure determinations of Pyrrolidine-2,4-diones, 2-IminoPyrrolidin-5-ones and 1,3-Oxazine-2,4-diones derived from Acetoacetanilides. Heterocycles, 68, 3, pp465-474.
• R. O¿Kennedy, M. Burke, P. van Kampen, P. James, M. Cotter, W. Browne, C. Ó¿Fágáin and E. McGlynn. 2005. The First EU Science Olympiad (EUSO): a model for science education. Journal of Biological Education. Journal Of Biological Education, , pp58-61.
• J. Howarth, P. James , J. Dai. 2004. An exploration of the catalytic Sakurai reaction in the moisture stable ionic liquids [bmim]PF6 and [bmim]BF4. Journal Of Molecular Catalysis A-chemical, 214, 1, pp143-146.
• M. Sheridan, P. James and C. Healy. 2003. Novel Cycloadducts from the 1,3-Dipolar Cycloaddition Reactions of Triazolium-1-Imide 1,3-Dipoles.. Arkivoc, vii,, pp110-120.
• P. Passaniti, W.R. Browne, F.C. Lynch, D. Hughes, M. Nieuwenhuyzen, P. James, M. Maestri and J.G. Vos. 2002. Synthesis, spectroscopic and electrochemical properties of mononuclear and dinuclear bis (bipy)ruthenium(II) complexes containing dimethoxyphenyl(pyridin-2-yl)-1,2-4-triazole ligands.. Journal Of The Chemical Society-dalton Transactions, *,, pp1740-*.
• T.B.H.McMurry, A.G. Murphy, D.N. Work, A.G. Avent and J.P. James. 2002. Photochemistry of cyclic enones. Part13. Intermolecular addition of styrene and 1-phenylprop-1-enes with 3-phenylcyclopentenone and 3-phenylcyclohexenone.. Journal Of Chemical Research-s, *,, pp317-*.
• W.R. Browne, C.M. O'Connor, J.S. Killeen, A.L.Guckian, M. Burke, P.James , M. Burke,J.G. Vos. 2002. Routes to regioselective deuteriation of heteroaromatic compounds.. Inorganic Chemistry, 41,, pp4245-*.
• J. Howarth, P. James and J. Dai. 2001. Immobilized baker's yeast reduction of ketones in an ionic liquid, [bmim]PF6 and water mix.. Tetrahedron Letters, 42,, pp7517-*.
• J. Howarth, P. James and R.Ryan. 2001. Sodium borohydride reduction of aldehydes and ketones in the recyclable ionic liquid [bmim]PF6. J. Howarth, P. James and R.Ryan. Synthetic Commun, 31 (19),, pp2935-*.
• J. Howarth, P. James and J. Dai. 2000. The coupling of aryl halides in the ionic liquid [bmim]PF6. J. Howarth, P. James and J. Dai Tetrahedron Letters, 2000, 41, 10319. Tetrahedron Letters, 41,, pp10319-*.
• N. Comey, A.I. Gray, I.L.Hook, P. James and H.Sheridan,. 1999. Sesquiterpene Lactones from Leontopodium Alpinum.. Phytochemistry, 50 (6),, pp1057-1060.
• D. Egan, P. James, D. Cooke and R.O'Kennedy,. 1997. Studies on the cytostatic and cytotoxic effects and mode of action of 8-nitro-7-hydroxycoumarin.. Cancer Letters, 118,, pp201-*.
• N. Comey, I. Hook, H. Sheridan, J.Walsh and P. James. 1997. Isolation of (S)-(-)-2,3-Dihydro-2,6-dimethyl-4H-benzopyran-4-one from Roots of Leontopodium alpinum.. Journal Of Natural Products, 60,, pp148-*.
• C. Byrne, J.P. James, C. Long and D. Wilcock. 1996. The Photochemical Transformation of Cyclic Azimines: X-Ray Crystallography Analysis of Intermediates in their Sequential Phototransformations.. Chemical Communications, *,, pp945-*.
• C. Byrne, S.M. Draper, J.P. James and C.Long. 1995. Synthesis and Crystal Structure of a Substituted 2,5,6,7-Tetrahydro-1,2,3,5-Tetrazocine: Photochemical Transformations of Substituted Pyrrolo [2,3-d]-1,2,3-Triazoles.. Journal Of Chemical Research-s, *,, pp2501-*.
• R.O'Connor, R.O'Kennedy and P. James. 1995. Use of proton NMR spectroscopy in the toxicological evaluation of new antimycobacterial agents.. Biochemical Society Transactions, 23,, pp357s-*.
• S.T. Atkinson, S.P. Brady, J.P. James and K.B. Nolan. 1995. Synthetic Haems as Mimics for High Valent Intermediates in Haemoprotein Catalysed Oxidations. Synthesis and Oxidation of Chloro-7,8,17,18-tetracyano-5,10,15,20-tetraphenylporphyrinatoiron (III), a Haem which Contains Strongly Electron-Withdrawing Groups in the b-Pyrrole positions. S.T. Atkinson, S.P. Brady, J.P. James and K.B. Nolan. Pure & Applied Chemistry, 1995, 67,1109.. Pure Appl Chem, 67,, pp1109-*.
• J.A. Bolger, G. Ferguson, J.P. James, C. Long, P. McArdle and J.G. Vos. 1993. Synthesis, Characterisation and Variable Temperature NMR Studies of Ruthenium(bipyridyl) Complexes Containing Dihydrazone Ligands. Journal Of The Chemical Society-dalton Transactions, *,, pp1577-*.
• P.V. Kavanagh, J.M. Kelly, T.B.H. McMurry and J.P. James,. 1993. Intramolecular Photocyclisation of Molecules containing both 3- Phenylcyclopentenone and uracil rings.. Chemical Communications, *,, pp231-*.
• A.M. Canning, I. Hook, H. Sheridan, J.P. James, D.R. Kelly. 1992. Bisradicinin: A Novel Dimer Elicited in Cultures of a Alternari Chrysanthemi.. Journal Of Natural Products, 55(4),, pp487-*.
• C.A. Downey, J.P. James, J. Lawler, P. O'Malley and S.Wolfe. 1992. Azoacetates as Synthons for the Azetidinone and Diazetidinone Ring Systems.. Chemical Communications, *,, pp454-*.
• H. Sheridan, C. Smyth, A.M. Canning, J.P. James. 1992. Stereoselective Reduction of Radicinin by Liquid Cultures of Alternaria Longipes.. Journal Of Natural Products, 55(7),, pp986-*.
• D.A.Egan, P.James and R.O'Kennedy. 1991. The Production and Characterisation of a coumarin-bovine serum albumin (BSA) conjugate and its use for antibody production.. Biochemical Society Transactions, 19(1),, pp57S-*.
• H.Sheridan, S.Lemon, N.Frankish, P.McArdle, T.Higgins, P.James and P.Bhandar. 1990. Synthesis and antispasmodic activity of nature identical substituted indanes and analogues.. Eur J Med Chem, 25,, pp603-*.
• J.Byrne, P.James, I.McMurrough and T.Tynan. 1990. Preparation and Analysis by High Performance Liquid Chromatography of Humulinic Acids, Dehydrohumulinic Acids and Hulupones.. Journal Of The Institute Of Brewing, 96,, pp137-*.
• R.N.Butler, A.M.Evans, A.M.Gillan, J.P.James, E.M. McNeela, D.Cunningham and P.McArdle. 1990. Azapropellanes: New Fused Tetra-azatriazolo[n.3.3.0]- dodecenes and trideceenes. Substituted 3,3a,4,5,6,6a-Hexahydropyrrolo [2,3-d]-1,2,3-triazoles from a General Tandem Cycloaddition- Rearrangement Reaction of 1,2,3- Triazolium Imides with Substituted Alkenes: Kinetics and Mechanism: Azolium 1,3-Dipoles.. Journal Of The Chemical Society-perkin Transactions 1, *,, pp2537-*.
• A.Long, P.James and O.P.Ward,. 1989. Aromatic Aldehydes as Substrates For Yeast and Yeast Alcohol Dehydrogenase.. Biotechnology And Bioengineering, *,, pp657-*.
• R.N.Butler, A.M.Gillan, J.P.James and A.M.Evans,. 1989. Regioselective Intramolecular Rearrangements in 1,2- Bis(areneazo)Cycloalkenes via Triazolium Imide 1,3-Dipoles: Examples of a New Fischer Indole-type Rearrangement. Azolium 1,3-Dipoles.. Journal Of The Chemical Society-perkin Transactions 1, *,, pp159-*.
• R.N.Butler, A.M.Gillan, J.P.James, P.McArdle and D.Cunningham. 1989. 2-(p-Nitroanilino)-3-[2-(p-nitrophenyl)-1,2-dihydro- phthalazin-1-yl] isoindolin-1-one. An unusual Dimer from Phthalaldehyde Mono-p- nitrophenylhydrazone.. Journal Of Chemical Research-s, *,, pp62-*.
• G.F.Killeen, C.A.Madigan, C.A.Connolly, G.A.Walsh, C.A.Clark, M.J.Hynes, B.F.Timmins, P.James, D.R.Headon and R.F.Power. 1988. The antimicrobial saponins of Yucca Schidigera and the implications of their in vitro properties for their in vivo impact. J. Agric., Food Chem., 1998, 46, 3178.. Journal Of Agricultural And Food Chemistry, 46,, pp3178-*.
• I.McMurrough, J.Byrne, E.Collins, M.R.Smyth, J.Cooney, P.James. 1988. Automated and Manual In-line Solid-Phase Sample Preparation for HPLC Analysis of Bittering Substances in Worts and Beers.. Journal Of The American Society Of Brewing Chemists, *,, pp51-*.
• R.N.Butler, A.M.Gillan, S.Collier and J.P.James. 1987. A Variable-temperature 270Mhz Nmr. Study of Structure and Dynamic Effects in 1,2-Bis(arylazo)cycloalkenes: a Degenerate Heterocyclic Rearrangement and Restricted Rotation of an N-aryl Bond. Journal Of Chemical Research-s, *,, pp332-*.
• R.N.Butler and J.P.James,. 1983. Regioselective Intramolecular Rearrangements in 1,2-Bis(areneazo)-cyclohexenes derived from Oxidations of Cyclohexane-1,2-dione Bis(arylhydrazones).. Journal Of The Chemical Society-chemical Communications, *,, pp627-*.
• R.N.Butler, D.Cunningham, J.P.James and P.McArdle. 1983. A New Fused Tricyclic Tetra-aza[4,3,3,0]dodecene System: Substituted 3,3a,4,5,6,6a- Hexahydropyrrolo[2,3-d]-1,2,3-triazoles from the Reaction of Acrylonitrile with cis-1,2-Bis(areneazo)ethylenes and a Re-assessment of 1,3-Cycloaddition Products.. Journal Of The Chemical Society-chemical Communications, *,, pp762-*.
• R.N.Butler and J.P.James. 1982. Reactions of Mercury(II) Acetate with Nitrogen Compounds. Oxidations of the Bis- (4-nitrophenylhydrazone)s of Some 1,3-Diketones with Mercury(II) Acetate and Lead(IV) Acetate.. Journal Of The Chemical Society-perkin Transactions 1, *,, pp553-*.
• R.N.Butler and J.P.James,. 1982. Oxidations of Some Substituted 1,4-Bis(hydrazone) Systems with Metallic Acetates: Synthesis of Phthalazines and 1,3-Dihydroisobenzofurans. Journal Of Chemical Research-s, *,, pp348-*.