Registry

Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title Instrumentation, Computing & Intro to Bioinfo
Module Code BE258
School School of Biotechnology
Online Module Resources

Module Co-ordinatorSemester 1: Phil Cummins
Semester 2: Phil Cummins
Autumn: Phil Cummins
NFQ level 8 Credit Rating 5
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None
Description
To introduce students to the theory and practice of analytical instrumentation and bio-computation.

Learning Outcomes
1. Explore biological databses, manipulate and organise biological data.
2. Estimate homology using computational methods
3. Calculate multiple sequence alignments using data gathered by themselves.
4. Describe spectrophotometry, chromatography, atomic adsorption spectophotometry, fluorimetry
5. Practise the use of various instruments used in biological anlayses
6. Outline the mathematics and computations components involved in generating analytical results



Workload Full-time hours per semester
Type Hours Description
Laboratory48Biocomputation and instrumental laboratories
Independent learning time77report writing and independent reading time
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities
Indicative Syllabus.
Theoretical overview of the mode of operation of each instrument listed in the practical set.Interfacing of instruments with personal computers.Modes of interfacing/communication between devices and computers.Installation of hardware and driver software in pseronal computers.New standards in communication.Interpretive software and the fundamentals of signal treatment.Introduction to computing, computer hardware and software and database technology.Networks, internet and enabling technologies.Interfacing peripheral devices.Inroduction to Bioinformatics.Databses:Primary, secondary and tertiary databases.Search algorithms and statistics.Multiple sequence alignment..

practical set.
The determination of alcohol in beveragesusing the Carl Erba Gas chromatograph.The determination of the absorption spectrum of prodigiosin, a pigment secreted by SErratia marcesens using a single beam and double beam spectrophotometer.The determination of copper in water using the Perkin Elmer 3100 Atomic absorption spectrophotometer.Shimadzu HPLC start-up procedure and measurement of column efficiency.Separation of a gas mixture using thermal conductivity detector series 550 GOW-MAC gas chromatograph.Determination of caffeine in beverages using VArian HPLC.Fatty acid analysis using Varian GC-Wipe tests for 3H and 14C detection using BEckmann LS6500.Riboflavin determination in commercial vitamin tablets using Perkin Elmer fluorimeterATP detection using LUMINOSKAN.Introduction to computing, databases, networks and data mining.Efficient use of biological databases.Protein analysis, BLAST, multiple sequence alignment.Profile identification.protein fingerprinting..

Assessment Breakdown
Continuous Assessment100% Examination Weight0%
Course Work Breakdown
TypeDescription% of totalAssessment Date
Reassessment Requirement
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category 2
Indicative Reading List
    Other Resources
    None
    Array
    Programme or List of Programmes
    GCBBSc in Genetics & Cell Biology
    Timetable this semester: Timetable for BE258
    Date of Last Revision18-AUG-09
    Archives:
    DCU
    Address
    The Helix
    3U
    NDP
    Government
    EU
    Disclaimer | Privacy