Registry

Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title	Bioreactors and Primary Separations
Module Code	BE322
School	School of Biotechnology
Online Module Resources
Module Co-ordinator	Semester 1: Greg Foley Semester 2: Greg Foley Autumn: Greg Foley
Module Teacher	Greg Foley
NFQ level	8	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

To understand the design and operation of bioreactors as well as techniques for removal of cells, disruption of cells and separation of cell debris.

Learning Outcomes

1. Understand bioreactor design and operation including Process Analytical Technologies (PAT)
2. Understand simple PID control and be able to simulate same with Polymath
3. Be able to apply engineering principles to heat, mass transfer and momentum transfer in bioreactors
4. Determine scale-up effects in bioreactor processes
5. Discuss and analyse the operation of cell disruption techniques
6. Formulate and apply equations for dead-end and crossflow filtration
7. Formulate and apply equations for centrifugation.

Workload	Full-time hours per semester
*Type*	*Hours*	*Description*
Lecture	24	No Description
Tutorial	12	No Description
Independent learning time	89	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Bioreactor construction and instrumentation, including process analytical technologies..
Heat, mass and momentum transfer in bioreactors.

Scale up.
Control of bioreactors.

Cell disruption.
Dead-end and crossflow filtration.

Centrifugation.

Assessment Breakdown
Continuous Assessment	0%	Examination Weight	100%

Course Work Breakdown
Type	Description	% of total	Assessment Date

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List

B. Atkinson and F. Mavituna: 1991, Biochemical Engineering and Biotechnology Handbook, 2nd Ed., Macmillan, 1561590126
P. Doran: 1995, Bioprocess Engineering Principles, P. Doran, Academic Press, London, 0122208552
H.W. Blanch and D.S. Clark: 1996, Biochemical Engineering, Marcel Dekker, New York, 0824789490
J.D. Bu'Lock and B. Kristiansen: 1987, Basic Biotechnology, Academic Press, London, 0121407527
A.H.Scragg: 1991, Bioreactors in Biotechnology - A Practical Approach, E. Horwood, New York, 0130851434
J.E. Bailey and D.F. Ollis: 1986, Biochemical Engineering Fundamentals, 2nd, McGraw-Hill, New York, 0070032122

Other Resources

None

Array

Programme or List of Programmes

BSSA

Study Abroad (DCU Business School)

BSSAO

Study Abroad (DCU Business School)

BSc in Biotechnology

ECSA

Study Abroad (Engineering & Computing)

ECSAO