Registry

Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title	Immunology and Immunoanalysis
Module Code	BE433
School	School of Biotechnology
Online Module Resources
Module Co-ordinator	Semester 1: Paul Leonard Semester 2: Paul Leonard Autumn: Paul Leonard
NFQ level	8	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

This purpose of this module is to provide a detailed understanding of the theory and applications of advanced aspects of immunology. Students will be given an in depth insight into the advantages and limitations of immunoanalytical approaches in clinical, industrial and research situations.

Learning Outcomes

1. Explain the molecular factors that confer immunogenicity to antigens
2. Describe in detail the cellular components involved generating immunity
3. Discuss in detail the methods used to produce antibodies and their appropriate applications
4. Discuss how antibody-based therapy can be used to treat human disease
5. Describe aspects of immunoanalysis including cytometry, immuno-cytochemistry, sensors and antibody-based targeting of ligands
6. Outline the importance of assay validation and research ethics

Workload	Full-time hours per semester
*Type*	*Hours*	*Description*
Lecture	24	No Description
Seminars	2	No Description
Tutorial	4	No Description
Independent learning	95	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Immunology.
The Process of antibody production at the cellular level; Intrinsic and extrinsic factors that influence antigenicity; Detailed account of B-cell stimulation; Antigen processing within the B-cell; The function and structure of the major histocompatibility antigens (MHC); The interaction of B-cells and T-cells; Genetic control of the immune response; Latest advances in understanding self, and non-self immune responses..

Immunoanalysis.
Methods of antibody production (in detail) including polyclonal, monoclonal, bifunctional, multifunctional, genetic methods and production of antibody-derived fragments; Genetics of antibody production and phage display; Reshaped, chimaeric and human antibodies-production and applications; Use of antibodies in cancer including diagnosis,imaging and treatment; Production and application of conjugates used for the generation of antibodies and in immunoanalysis, Detailed account of immunocytochemistry and its applications;Introduction to next generation diagnostic devices..

Assessment Breakdown
Continuous Assessment	0%	Examination Weight	100%

Course Work Breakdown
Type	Description	% of total	Assessment Date

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List

Ivan M. Roitt, Seamus J. Martin, Peter J. Delves, Dennis Burton,: 0, Roitt's Essential Immunology, 978-1-4051-3603-7
Kenneth M. Murphy, Paul Travers, Mark Walport: 2008, Janeway's immunobiology, Garland Science, New York, 978-0-8153-4123-9

Other Resources

None

Array

Programme or List of Programmes

BSSA

Study Abroad (DCU Business School)

BSSAO

Study Abroad (DCU Business School)

BSc in Biotechnology

ECSA

Study Abroad (Engineering & Computing)

ECSAO