Registry

Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title	Biomolecular Anal. Nucleic Acids and Proteins
Module Code	BE511
School	School of Biotechnology
Online Module Resources
Module Teacher	Ronan Murphy
NFQ level	8	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

To provide a detailed understanding of: The structure and function of proteins and nucleic acids. The development of the methodology used both for the purification and subsequent analysis of the above. The diagnostic applications that have been developed based on nucleic acids and immunoglobulins.

Learning Outcomes

1. Students should have a good appreciation of how a thorough understanding of both the physical and chemical properties of biological molecules not only enable their purification but together with ongoing technical developments make possible developments in the applied sciences.
2. Understand cutting edge technologies and their application to biomedical research.
3. Comprehension of novel findings and their relevance to biomedicine (potential use, commercialisation etc.)

Workload	Full-time hours per semester
*Type*	*Hours*	*Description*
Lecture	36	Course material
Assignment	34	Literature review
Independent learning	40	Review of literature
Directed learning	15	Topic specific tuition
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

Indicative Syllabus.
The module is divided into two sections (2 x 12L). Part A.

Introduction to proteins.
Composition and structure. Physiochemical properties of proteins that can be exploited for their separation and analysis. Introduction to column chromatography. Immunoanalysis: Introduction to immunology: antibody diversity, clonal selection theory and somatic mutations, the structure of an antibody, immunogen and antigen. Production of polyclonal antibodies. Purification of antibodies. Making small molecules (haptens) antigenic. Production of monoclonal antibodies. Markers used to detect antibody binding. Immunological applications - solid phase enzyme linked immunosorbant assays (ELISA), radioimmunoassay and immunofluorescence microscopy.

Part B.

Assessment Breakdown
Continuous Assessment	0%	Examination Weight	100%

Course Work Breakdown
Type	Description	% of total	Assessment Date
Essay	Literature review	40%	Week 30

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List

Other Resources

None

Array

Programme or List of Programmes

GCPA

GradDip Adv Chemical Pharmaceut Analysis

MCPA

MSc Adv Chemical Pharmaceutical Analysis

Timetable this semester: Timetable for BE511

Date of Last Revision

01-OCT-08