Registry

Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title	Organic Chemistry
Module Code	CS204
School	School of Chemical Sciences
Online Module Resources
Module Co-ordinator	Semester 1: Paraic James Semester 2: Paraic James Autumn: Paraic James
NFQ level	8	Credit Rating	5
Pre-requisite	None
Co-requisite	None
Compatibles	None
Incompatibles	None

Description

To develop competence in the use of chemical structures and reaction schemes. To develop chemical intuition. To develop an understanding and familiarity with mechanistic concepts. To develop problem-solving skills. To develop the theoretical and conceptual background for laboratory work. To develop an appreciation of the industrial importance of organic chemistry and of the contribution of organic chemistry to society.

Learning Outcomes

1. Describe the main electrophillic substitution reactions of benzene.
2. Predict the location of disubstitution of aromatic rings.
3. Assign R,S stereochemistry
4. Sketch and explain the more stable conformers of substituted cyclohexane.
5. Distinguish between Nucleophilic substitution reactions SN1 or SN2, and outline the mechanism involved.Similiarly consider Electrophilic substitutions E1, E2.
6. Illustrate mechanisms involved, and products obtained, from reactions addressed on the course, such as Aldol condensation, Claisen condensation.

Workload	Full-time hours per semester
*Type*	*Hours*	*Description*
Lecture	36	No Description
Independent learning	89	No Description
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities

ORGANIC FUNCTIONAL GROUPS.
Review of their chemistry..

STEREOCHEMISTRY:.
Cyclohexane conformational analysis: axial/equatorial positions; chair-chair interconversions; geometrical isomerism and conformational free energies in substituted cyclohexanes; decalins/steroids; hexoses. Chirality: optical activity; polarimetry; centre of chirality; enantiomers; racemates and resolution; several chiral centres; diastereomers; relative and absolute configuration; R- and S- nomenclature; deficiencies of D- and L-nomenclature..

MECHANISMS OF NUCLEOPHILIC DISPLACEMENT:.
Kinetics and mechanism; transition state; the SN1 and SN2 processes; structural factors; optical isomerism, configuration and mechanism; solvent effects; Similiarly consider Electrophilic Substitutions E1 and E2..

CARBANION/ENOLATE CHEMISTRY:.
Relative acidities of C-H bonds in differing molecular environments; resonance stabilisation; effect of a second stabilising group; Aldol condensation; Claisen condensation and its variants; ethyl acetoacetate, diethyl malonate and ethyl cyanoacetate; synthetic applications of active methylene compounds..

AROMATIC CHEMISTRY:.
Benzene structure and electrophilic substitution reactions (nitration, halogenation, sulphonation,alkylation, acylation, metallation).Substituted benzenes: electrophilic substitution reactions of substituted benzene systems; rationalisation of activating and directive effects; survey of the chemistry of substituted benzenes in terms of sources, electrophilic substitution reactions and substituent chemistry - alkylbenzenes; nitrobenzenes; aromatic amines; diazonium salts; phenols; aryl halides (excluding nucleophilic aromatic substitution); aromatic carbonyl compounds.Aromaticity: the Hückel (4n+2) rule; polycyclic aromatics and their chemistry; introduction to annulenes and heteroaromatic systems..

Assessment Breakdown
Continuous Assessment	0%	Examination Weight	100%

Course Work Breakdown
Type	Description	% of total	Assessment Date

Reassessment Requirement
Resit arrangements are explained by the following categories; 1 = A resit is available for all components of the module 2 = No resit is available for 100% continuous assessment module 3 = No resit is available for the continuous assessment component
This module is category 1

Indicative Reading List