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Module Specifications

Current Academic Year 2012 - 2013
Please note that this information is subject to change.

Module Title
Module Code
School
Online Module Resources

NFQ level 9 Credit Rating
Pre-requisite None
Co-requisite None
Compatibles None
Incompatibles None
Description
This course will provide an introduction to the principles and applications of photonics in biology, with a special emphasis on the expanding usage of nano-structures in this area. Basic principles of biophotonics and nanotechnology will be introduced and developed towards the use of nano-particles, quantum dots and microarrays for bio-imaging, optical biosensing and micro-patterning of biological material.

Learning Outcomes
1. To develop an appreciation of the basic concepts behind nanomaterials and what distinguishes them from bulk materials
2. To appreciate the basic principles behind spectroscopic methods commonly exploited in nanobiophotonics, including absorbance spectroscopy, fluorescence, Raman spectroscopy
3. To understand the concept of plasmon and appreciate how it relates to enhancement of spectroscopic signal
4. Describe the operation of Surface Plasmon Resonance
5. Describe the coupling of selected nanotechnologies with biophotonics to advance knowledge in biology, biotechnology and biomedical science.
6. Define optical interactions with biological materials
7. Recognise optically driven bio-sensors and nanotechnology driven bio-imaging techniques.
8. Describe plasmonics and optically driven nanotechnologies such as quantum dots and microarrays and their interaction with biotechnology.
9. Evaluate state of the art research in the field of nanobiotechnology



Workload Full-time hours per semester
Type Hours Description
Assignment10Final assessment
Tutorial5On-line contact with course teacher
Library50Reading Material
Tutorial20Preparation for Tutorials
On-line learning40Course Notes
Total Workload: 125

All module information is indicative and subject to change. For further information,students are advised to refer to the University's Marks and Standards and Programme Specific Regulations at: http://www.dcu.ie/registry/examinations/index.shtml

Indicative Content and Learning Activities
Light-matter interactions.
Absorption of radiation, UV-visible spectroscopy, fluorescence spectroscopy, quenching, scattering of radiation, Raman scattering, Mie scattering..

Materials.
Extrinsic Fluorophores, Quantum Dots, noble metal nanoparticles, PEBBLES, molecular beacons, USPIO.

Bio-Imaging.
Cell imaging, Fluorescence lifetime imaging, Quantum Dot imaging, Bio-luminescence.

Biosensing.
Sensor features, Sandwich assay, Surface Plasmon Resonance, Surface enhanced Raman spectroscopy, Near Infra-red absorption nanoparticles, Drug delivery.

Micro-arrays.
Basics of DNA, Fluorescence in-situ hybridisation, Genome sequencing, Protein arrays, Biochips.

Plasmonics.
Localised surface Plasmon resonance, Plasmon enhanced fluorescence, Nano-sphere lithography, plasmonic structures, nano-medicine..

Assessment Breakdown
Continuous Assessment% Examination Weight%
Course Work Breakdown
TypeDescription% of totalAssessment Date
AssignmentProblems containing quantitative, description and design based questions to test all learning outcomes, 1-9.100%n/a
Reassessment Requirement
Resit arrangements are explained by the following categories;
1 = A resit is available for all components of the module
2 = No resit is available for 100% continuous assessment module
3 = No resit is available for the continuous assessment component
This module is category
Indicative Reading List
  • P.N. Prasad: 2003, Introduction to Biophotonics, Wiley-Interscience,
  • T. Vo-Dinh: 2003, Biomedical Photonics Handbook, CRC Press,
  • C.A. Niemeyer and C.A. Mirkin: 2004, Nanobiotechnology: Concept, Applications and Perspective, Wiley-WHC,
  • J.G. Vos, R.J. Forster and T.E. Keyes: 2003, Interfacial Supramolecular Assemblies, Wiley,
  • J.R. Lakowicz: 2006, Principles of Fluorescence Spectroscopy, 3rd Ed., Springer,
  • R. Aroca: 2006, Surface-Enhanced Vibrational Spectroscopy, Wiley,
  • J.B. Rampal: 2001, DNA Arrays Methods and Protocols, Humana Press,
Other Resources
None
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