| Differentiation & Proteomics |  |
| Differentiation is the process through which
cells acquire their ultimate form and function. The lung is one of the most
important, but also one of the least understood, differentiation systems.
The Differentiation Group at the NCTCC has identified a novel in vitro cell
line model for studying human epithelial lung cell differentiation. The Differentiation Group is also studying the regulation of functional gene expression at the translational level. Using its model system, the group is investigating the role of specific elements of the translational machinery, translation initiation factors, in controlling protein expression during epithelial cell differentiation. Many of these genes/proteins have been linked to the development of cancer Research Areas
|
| Staff: | Paula Meleady |
| Finbar O'Sullivan |