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The following is a list of recent publications that describe the microfluidic technologies underpinning the FPC@DCU, which have been developed under a number of research programmes prior to its establishment, in particular the SFI-funded Biomedical Diagnostics Institute (BDI).

List of publications:

1]   Celina M. Miyazaki, Rohit Mishra, David J. Kinahan, Marystela Ferreira, and Jens Ducrée. Polyethylene imine/graphene oxide layer-by-layer surface functionalization for significantly improved limit of detection and binding kinetics for immunoassays on acrylate surfaces. Colloids & Interfaces B: Biointerfaces, 2017. status: accepted on 2017-06-26.

[2]   Emer Duffy, Rima Padovani, Xiaoyun He, Robert Gorkin, Elizaveta Vereshchagina, Jens Ducrée, Ekaterina Nesterenko, Pavel N. Nesterenko, Dermot Brabazon, Brett Paull, and Mercedes Vázquez. New strategies for stationary phase integration within centrifugal microfluidic platforms for applications in sample preparation and pre-concentration. Analytical Methods, 9(13):1998–2006, 2017, DOI:10.1039/C7AY00127D. cover article.

[3]   Gillian Duffy, Ivan Maguire, Brendan Heery, Charles Nwankire, Jens Ducrée, and Fiona Regan. PhosphaSense: A fully integrated, portable lab-on-a-disc device for phosphate determination in water. Sensors & Actuators B – Chemical, 246:1085–1091, July 2017, DOI:10.1016/j.snb.2016.12.040.

[4]   Des Brennan, Helena Coughlan, Eoin Clancy, Nikolay Dimov, Thomas Barry, David Kinahan, Jens Ducrée, Terry J. Smith, and Paul Galvin. Development of a system for on-disc isothermal amplification and detection of bacterial RNA. Sensors & Actuators B – Chemical, 239:235–242, February 2017, DOI:10.1016/j.snb.2016.08.018.

[5]   David J. Kinahan, Marine Renou, Dirk Kurzbuch, Niamh A. Kilcawley, Éanna Bailey, Macdara T. Glynn, Collette McDonagh, and Jens Ducrée. Baking powder actuated centrifugo-pneumatic valving for automation of multi-step bioassays. Micromachines, 7(10):175–184, 2016, DOI:10.3390/mi7100175.

[6]   Saraí M. Torres Delgado, David J. Kinahan, Fralett Suárez Sandoval, Lourdes A.N. Julius, Niamh A. Kilcawley, Jens Ducrée, and Dario Mager. Fully automated chemiluminescence detection using the electrified-Lab-on-a-Disc (eLoaD) platform. Lab on a Chip, 16(20):4002–4011, 2016, DOI:10.1039/C6LC00973E.

[7]   David J. Kinahan, Philip L. Early, Abhishek Vembadi, Eoghan MacNamara, Niamh A. Kilcawley, Thomas Glennon, Dermot Diamond, Dermot Brabazon, and Jens Ducrée. Xurography actuated valving for centrifugal flow control. Lab on a Chip, 16(18):3454–3459, 2016, DOI:10.1039/C6LC00568C.

[8]   Jennifer Gaughran, David Boyle, James Murphy, Robert Kelly, and Jens Ducrée. Phase-selective graphene oxide membranes for advanced microfluidic flow control. Nature Microsystems & Nanoengineering, 2:16008, 2016, DOI:10.1038/micronano.2016.8. selected as feature article on journal cover.

[9]   David J. Kinahan, Sinéad M. Kearney, Niamh A. Kilcawley, Philip L. Early, Macdara T. Glynn, and Jens Ducrée. Density-gradient mediated band extraction of leukocytes from whole blood through centrifugo-pneumatic siphon valving. PLoS ONE, 11(5):e0155545, 2016, DOI:10.1371/journal.pone.0155545.

[10]   Suzanne Smith, Dario Mager, Alexandra Perebikovsky, Ehsan Shamloo, David Kinahan, Rohit Mishra, Saraí M. Torres-Delgado, Horacio Kido, Satadal Saha, Jens Ducrée, Marc Madou, Kevin Land, and Jan Korvink. CD-based microfluidics for primary care in extreme point-of-care settings? Micromachines, 7(2):22–32, 2016, DOI:10.3390/mi7020022.

[11]   Macdara Glynn, Charles Nwankire, Kate Lemass, David Kinahan, and Jens Ducrée. Quantitative distribution and cluster sizing of CTC events from a blood sample using a size exclusion centrifugal rail.Nature Microsystems & Nanoengineering, 1:15018, 2015, DOI:10.1038/micronano.2015.18.

[12]   Ulrich-Christian Schröder, Frank Bokeloh, Mary O’Sullivan, Uwe Glaser, Katharina Wolf, Wolfgang Pfister, Jürgen Popp, Jens Ducrée, and Ute Neugebauer. Rapid, culture-independent, optical diagnostics of centrifugally captured bacteria from urine samples. Biomicrofluidics, 9(4):044118, 2015, DOI:10.1063/1.4928070.

[13]   Gregor S. Kijanka, Ivan K. Dimov, Robert Burger, and Jens Ducrée. Real-time monitoring of cell migration, phagocytosis and cell surface receptor dynamics using a novel, live-cell opto-microfluidic technique. Analytica Chimica Acta, 872:95–99, 2015, DOI:10.1016/j.aca.2014.12.035.

[14]   Nikolay Dimov, Eoin Clancy, Jennifer Gaughran, David Boyle, Darren Mc Auley, Macdara Glynn, Thomas Barry, Louise Barrett, Terry J. Smith, and Jens Ducrée. Solvent-selective liquid routing for centrifugally integrated solid-phase extraction of RNA. Microfluidics & Nanofluidics, 18(5-6):859–871, 2015, DOI:10.1007/s10404-014-1477-9.

[15]   Charles E. Nwankire, Anita Venkatanarayanan, Thomas Glennon, Tia E. Keyes, Robert J. Forster, and Jens Ducrée. Label-free electrochemical impedance detection of cancer cells from whole blood on an integrated centrifugal microfluidic platform. Biosensors & Bioelectronics, 68:382–389, 2015, DOI:10.1016/j.bios.2014.12.049.

[16]   Damien King, Cristina Rius Leiva, Macdara Glynn, Beatriz Julia Dorado de la Corta, Sandra Cindric, David Kernan, Vicente Andrés García, Andreu Llobera, Elise Røge Hedegaard, Ulf Simonsen, and Jens Ducrée. Living photonics (LiPhos) single cell analysis – Label free detection methods. Acta Physiologica, 215(706):32–33, September 2015, DOI:10.1111/apha.12602.

[17]   Robert Burger, Dirk Kurzbuch, Robert Gorkin, Gregor Kijanka, Macdara Glynn, Colette McDonagh, and Jens Ducrée. An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells. Lab on a Chip, 15(2):378–381, 2015, DOI:10.1039/c4lc01002g.

[18]   David Kinahan, Sinéad Kearney, Olivier Faneuil, Macdara Glynn, and Jens Ducrée. Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms. RSC Advances, 5(3):1818–1826, 2015, DOI:10.1039/C4RA14887H.

[19]   Daniel Kirby, Macdara Glynn, Gregor Kijanka, and Jens Ducrée. Rapid and cost-efficient enumeration of rare cancer cells from whole blood by low-loss centrifugo-magnetophoretic purification under stopped-flow conditions. Cytometry Part A, 87(1):74–80, 2015, DOI:10.1002/cyto.a.22588.

[20]   Gerson R. Aguirre, Vitaly Efremov, Maria Kitsara, and Jens Ducrée. Integrated micromixer for incubation and separation of cancer cells on a centrifugal platform using inertial and Dean forces. Microfluidics & Nanofluidics, 18(3):513–526, 2015, DOI:10.1007/s10404-014-1450-7.

[21]   Damien King, Macdara Glynn, Sandra Cindric, Richard Lalor, Tríona O’Connell, and Jens Ducrée. Utilising the microfluidic lab-in-a-trench platform to enable single cell level drug screening of hepatocytes.Acta Physiologica, 215(706):96, September 2015, DOI:10.1111/apha.12603.