Better reporting is better science: Community-defined minimal reporting requirements for light microscopy
Janosch Heller et al
Journal of Cell Biology
School of Biotechnology
Abstract

Microscopy is central to discovery in the biomedical and life sciences. Continuously evolving to meet researchers’ needs, it enables scientists to visualize and quantify the invisible and explore questions once thought beyond reach. Advances such as super-resolution imaging, spatial-omics, tissue clearing, and volumetric imaging, to cite just a few, continue to expand our ability to uncover the complexity of biological systems in unprecedented detail. To ensure these powerful techniques effectively drive discovery, detailed and transparent reporting of microscopy methods, including hardware specifications and other key metadata, is essential. Yet, despite imaging’s central role in most biomedical research, methodological details are still too often underreported (Marqués et al., 2020). Improving rigor and reproducibility in microscopy reporting is not merely a matter of compliance; it is an opportunity to strengthen the reliability and impact of our science: improving reporting accelerates discovery, enables others to build upon existing work, and reinforces confidence in published results.