School of Health and Human Performance
Name: Dr. Joshua Ong
Contact email address: firstname.lastname@example.org
For Qualification of Study: MD
Research Title: The Role of Neuromuscular Electrical Stimulation in the Management of Knee Arthritis
Young men and women with premature osteoarthritis of the knee joint who undergoes early joint replacement are likely to have revision surgery in < 10 years. Revision total knee arthroplasty is plagued with increased risks of complications. Neuromuscular electrical stimulation (NMES) causes muscle contraction by applying transcutaneous current to the neuromuscular junction and surrounding muscle fibres. A home-based NMES program may provide a safe and simple alternative to supervised resistance training for improving perioperative quadriceps strength in young men and women with knee OA. Dr, Ong's study examines the putative benefits of a 6 week NMES program on quadriceps size and strength, knee pain, and functional capacity in individuals with knee OA. In addition, changes in the IGF-1 hypertrophy pathway, myosin heavy chain isoform expression and the atrophy genes MuRF 1 and MAFbx are also examined.
Supervisor: Professor Niall Moyna