Name: Robert Wallace
Contact telephone number: +353 (0)1 1700 8824
Contact e-mail address: email@example.com
Qualifications to date: B.Sc (Hons.) Bioanalytical Science
Currently completing Ph.D at Dublin City University
Research title: Epigenetic re-modelling of the vascular interior
Year commenced: 2012
Anticipated year of completion: 2016
Supervisor: Dr. Ronan Murphy
My research focuses on the epigenetic changes caused to vascular cells due to differing types of blood flow. Blood vessels are readily capable of re-modelling/altering themselves in response to hemodynamic prompts associated with variations in blood flow, implying an epigenetic response. Hence, we investigate and define these changes through in vitro organotypic modelling of the vascular interior, with subsequent analysis of extracted genetic material (RNA and microRNA). Advanced technological platforms, such as the Ibidi® perfusion system, enable fine control of the cellular micro-environment and facilitate a wide variety of experimental investigations.
This work was funded by the Irish Research Council (IRC).