Researcher Details |

Donal O'Gorman

Dr.

Dr. Donal O’Gorman is Interim Director of the National Institute for Cellular Biotechnology (NICB), a leading research institute located on the DCU campus in Dublin. The NICB is a major focus for cell and molecular biology research in Ireland, in particular as it interacts with clinical translational research in the cancer, diabetes and ocular disease areas, and with the Biopharma and other bioscience-related industry.

Dr. O'Gorman also leads the 3U Diabetes Partnership, an initiative integrating the research expertise of DCU, the Royal College of Surgeons in Ireland and the Maynooth University. In addition, he is Deputy Director of the National Institute for Cellular Biotechnology at DCU. Dr. O’Gorman’s research focuses on metabolic physiology, in particular the regulation of insulin sensitivity and energy expenditure as well as the cellular regulation of gene expression and mitochondrial function.

Dr. O’Gorman has a strong track record of working on large scale, collaborative, European research projects. DEXLIFE is an EU FP7 collaborative project to identify biomarkers that better predict the onset of type 2 diabetes and INTERCONNECT is a global initiative on diabetes gene-environment. In addition, he is on the management committee of the Joint Programming Initiative (JPI) on Diet and Diet related diseases (DEDIPAC), heads a European Space Agency group on metabolism and is a member of the ESF funded roadmap for space research in Europe (THESEUS).

In 2010 he was a co-recipient of the XII National award for research on Sports Medicine in Spain. He was a member of the National Task Force on Obesity in Ireland, a former president of the Exercise and Sport Science Association of Ireland and is currently on the editorial board of the American Journal of Physiology: Endocrinology and Metabolism

Conference Contribution

	Year	Publication
		O'Donghaile, D., O'Gorman, D.J., Yousif, O., and Nolan, J.J. Irish Endocrine Society The investigation of the Pro12Ala polymorphism of PPAR?2 in an Irish diabetes population Ireland, .
		O'Gorman, D. Association of Clinical Biochemists of Ireland,2002 Exercise in the prevention and treatment of Type 2 diabetes Ireland, .
		Kirwan, J.P., R.K. Krishnan, D.L. Williamson, D.J. O'Gorman, J.M. Hernandez, P.A. Farrell, and W.J. Evans. Gerontology Conference, 1997 Effects of eccentric resistance exercise on the pancreatic b-cell response to hyperglycemia in 59-73 year old healthy men United States, .
		R.K. Krishnan, J.M. Hernandez, D.L. Williamson, D.J. O'Gorman, W.J. Evans, and J.P. Kirwan. American Diabetes Association Delayed Glucose Clearance In Healthy Older Men Is Related To Abdominal Adiposity United States, .
		Kirwan, J.P., D.J. O'Gorman, D. Campbell, G. Sporay, and W.J. Evans. American College of Sports Medicine Conference, 1996 A low glycemic meal 45 minutes before exercise improves performance United States, .
		Williamson, D.L., R.K. Krishnan, D.J. O'Gorman, C. Lakatta, J.M. Hernandez, W.J. Evans, and J.P. Kirwan. American College of Sports Medicine Conference, 1996 A single bout of resistance exercise increases basal metabolic rate in healthy 60-70 year old men United States, .
		Kirwan, J.P., Krishnan, R.K., Marchetti, C.M., Williamson, D.L., del Aguila, L.F., O'Gorman, D.J., and Stetzer, B.P Gerontology Conference Effects of age on free fatty aid induced insulin resistance United States, .
		O'Gorman, D.J., Yousif, O., O'Donghaile, D., Gasparro, D., and Nolan, J.J. . Irish Endocrine Society Exercise training improves insulin sensitivity and the insulin resistance syndrome in Type 2 diabetes Ireland, .
		Chan, S.N., O'Gorman, D.J., Yousif, O., and Nolan, J.J. Irish Endocrine Society 2001 Physiological and metabolic profiling of women with Type 2 diabetes and former gestational diabetes Ireland, .
		Kirwan, J.P., D.J. O'Gorman, D. Campbell, K.E. Yarasheski, and W.J. Evans. American College of Sports Medicine Conference, 1997 Effects of a pre-exercise breakfast cereal on exercise performance and glucose production United States, .
		O’Gorman, D.J., McQuaid, S., Yousif, O., Rahman, Y., Gasparro, D., Yeow, T.P. and Nolan, J.J. Association of Clinical Biochemists of Ireland, 2002 Exercise mediated enhancement of whole body glucose disposal and intra-cellular insulin signalling: the prevention of Type 2 diabetes .
		MacDonncha, C., S. McGrath, D.J. O’Gorman, G.D. Warrington American College of Sports Medicine 2003 The relationship between muscle flexibility and sagittal spinal posture in Gaelic Football players USA, .
		R. Sohun, C. MacDonncha, S.McGrath, DJ O’Gorman, E. McGowan, G.D.Warrington American College of Sports Medicine 2003 The impact of an exercise and mutritional intervention on physiological function in manual employees USA, .
		O’Gorman, D.J., S. McGrath, G. Warrington, C. MacDonncha. American College of Sports Medicine 2003 The role of physical fitness screening in the recruitment of Irish fire fighters USA, .
		McQuaid, S., O’Gorman, DJ, Cosgrove, J., Yeow, TP, Mulvihill, N., and Nolan, JJ Irish Angiology Conference 2003 Endothelial dysfunction in obese and early onset Type 2 diabetes subjects. I Ireland, .
		O’Gorman, D.J., McQuaid, S., Karlsson, H., Yousif, O., Gasparro, D., Chibalin, A., Zierath, J.R., Nolan, J.J. International Biochemistry of Exercise Conference 2003 The effect of acute and chronic exercise on glucose disposal and PI3-K activity in obese and Type 2 diabetes patients The Netherlands, .
		O’Gorman, D.J., McQuaid, S., Karlsson, H., Yousif, O., Gasparro, D., Chibalin, A., Zierath, J.R., Nolan, J.J. Association of Physicians 2004 IRS-1, IRS-2 and phosphotyrosine associated PI3-K activity following exercise in subjects with Type 2 diabetes Ireland, .
		F AlSaraj, D O’Gorman, S McAteer, Z Hawi and S Sreenan. Irish Endocrine Conference 2005 A study of variation in the Calpain 10 Gene in Irish Patients with Type 2 Diabetes Mellitus Ireland, .
		F. AlSaraj, H. Thabit, D. O’Gorman, S. McAteer, Z. Hawi, S.K. Sreenan American Diabetes Association Conference 2006 Variation in the Calpain 10 Gene in Irish Patients with Type 2 Diabetes Mellitus .
		Kirwan, J.P., J.M. Hernandez, L.F. del Aguila, D.L.Williamson, D.J. O'Gorman, M.R. Lewis, and R.J. Krishnan. American Diabetes Association, 1998 Effects of exercise training on insulin mediated phosphatidylinositol 3-kinase activation in human skeletal muscle Boston, USA, .
		Krishnan, R.K., J.M. Hernandez, D.L. Williamson, D.J. O'Gorman, W.J. Evans, and J.P. Kirwan. American College of Sports Medicine Conference, 1998 Age-related differences in the pancreatic b-cell response to hyperglycemia following eccentric exercise United States, .
		Yousif, O., O'Gorman, D.J., O'Donghaile, D., Gasparro, D., Pacini, G., Lavin, C. and Nolan, J.J. Irish Endocrine Society, 2001 Fast acting insulin secretagogues improve glycaemic control in Type 2 diabetes Kerry, .
		O. Yousif, D.J. O'Gorman, D. O'Donghaile, D. Gasparro, G. Pacini and J. J. Nolan. American Diabetes Association GAD Positive Type 2 Diabetes: Insulin Resistance with a Pronounced Defect in First Phase Insulin Secretion Philadelphia, USA, .
		O'Gorman, D.J., Yousif, O., O'Donghaile, D., Murphy, E., Gasparro, D., Pacini, G. and Nolan, J.J. European Congress on Obesity Early Onset Type 2 diabetes: Severe Obesity with Classical Insulin Resistance Phenotype Vienna, Austria, .
		E. Murphy, D.J. O'Gorman, G. Pacini, D. Gasparro, K.L. Jones, and J.J. Nolan. European Association for the Study of Diabetes Annual Meeting Type 2 diabetes in Mexican American and Caucasian adolescents and young adults: a similar metabolic phenotype Israel, .
		Kirwan, J.P., R.K. Krishnan, S.N. Sistrun, D.L. Williamson, R. Lewis, D.J. O'Gorman, L.F. del Aguila, D.A. Kriz, and C.M. Marchetti. Gerontology Conference Decreased visceral fat after exercise and caloric reduction is related to improved glucose tolerance in 57-77 year old obese men and women with impaired glucose tolerance (IGT) United States, .
		O'Gorman, D.J., L.F. del Aguila, M.R. Lewis, D.L. Williamson, and J.P. Kirwan. European College of Sports Science Annual Conference ERK-1 phosphorylation following exercise and feeding United Kingdom, .
		O’Gorman, D.J., McQuaid, S., Yousif, O., Rahman, Y., Gasparro, D., Yeow, T.P. and Nolan, J.J. Irish Endocrine Society 2002 The effects of acute and chronic exercise on insulin sensitivity in obesity and type 2 diabetes .
		S.McQuaid, Y.Rahman, O.Yousif, D.J.O’Gorman, D. Gasparro, J.J. Nolan Irish Endocrine Society 2002 The Clinical and Metabolic Features of Irish Patients with Acanthosis Nigricans .
		Kirwan, J.P., Krishnan, R.K., Marchetti, C.M., Williamson, D.L., del Aguila, L.F., O’Gorman, D.J., and Stetzer, B. Gerontology Conference, 2002 Effects of age on free fatty aid induced insulin resistance .
		S. McQuaid, Y. Rahman, D.J. O’Gorman, O Yousif, D. Gasparro, J.J. Nolan. European Chapter of the American Association of Clinical Nutrition, 2002 The clinical and metabolic features of Irish patients with Acanthosis Nigricans Greece, .
		del Aguila, L.F., D.J. O'Gorman, M.R. Lewis, D.L. Williamson, and J.P. Kirwan. European College of Sports Science Annual Conference, 1998 Differential activation of PI3-K following a single bout of exercise and a physiological feeding United Kingdom, .
		Lewis, M.R., D.L. Williamson, D.J. O'Gorman, L. F. del Aguila, R.K. Krishnan, and J.P. Kirwan. American College of Sports Medicine Conference 1998 Free fatty acid suppression of insulin mediated glucose metabolism in older overweight individuals United States, .
		O'Connor, A.M., C.F. Johnson, D.J. O'Gorman, J.P. Kirwan, K.D. Buchnan, and K. Alberti. Hormone Research Conference,1995 Glucose intolerance following endurance exercise *, .
		O'Gorman, D.J., A. Hunter, C. MacDonncha, and J.P. Kirwan. American College of Sports Medicine Conference, 1996 Validity of field tests as predictors of aerobic capacity in athletes United States, .

Conference Publication

	Year	Publication
	2019	1. Barrett C, O'Sullivan F, Barry S, Grygoryev K, O’Gorman D, O'Mahony C, O’Riordan A. (2019) Proceedings of IEEE Sensors *Novel Surface Modified Polymer Microneedle based Biosensors for Interstitial Fluid Glucose Detection*
	2015	Deignan J.;Monedero J.;Coyle S.;O'Gorman D.;Diamond D.;McBrearty M. (2015) *2015 IEEE 12th International Conference on Wearable and Implantable Body Sensor Networks, BSN 2015*

Book Chapter

	Year	Publication
	2014	Nolan J.;O'Gorman D. (2014) 'Pathophysiology of the metabolic syndrome' In:
	2005	O'Gorman DJ, Nolan JJ. (2005) 'Exercise in Diabetes and Obesity' In: Gormley J and Hussey J(Eds.). United Kingdom : Blackwell Publishing.

Peer Reviewed Journal

	Year	Publication
	2020	Kenny H.C.;Tascher G.;Ziemianin A.;Rudwill F.;Zahariev A.;Chery I.;Gauquelin-Koch G.;Barielle M.P.;Heer M.;Blanc S.;O'Gorman D.J.;Bertile F. (2020) 'Effectiveness of Resistive Vibration Exercise and Whey Protein Supplementation Plus Alkaline Salt on the Skeletal Muscle Proteome Following 21 Days of Bed Rest in Healthy Males'. Journal of Proteome Research, 19 (8):3438-3451.
	2019	Capella Roca B.;Alarcón Miguez A.;Keenan J.;Suda S.;Barron N.;O’Gorman D.;Doolan P.;Clynes M. (2019) 'Zinc supplementation increases protein titer of recombinant CHO cells'. Cytotechnology, .
	2017	Brug J.;van der Ploeg H.;Loyen A.;Ahrens W.;Allais O.;Andersen L.;Cardon G.;Capranica L.;Chastin S.;De Bourdeaudhuij I.;De Craemer M.;Donnelly A.;Ekelund U.;Finglas P.;Flechtner-Mors M.;Hebestreit A.;Kubiak T.;Lanza M.;Lien N.;MacDonncha C.;Mazzocchi M.;Monsivais P.;Murphy M.;Nicolaou M.;Nöthlings U.;O'Gorman D.;Renner B.;Roos G.;van den Berg M.;Schulze M.;Steinacker J.;Stronks K.;Volkert D.;Lakerveld J. (2017) 'Determinants of diet and physical activity (DEDIPAC): A summary of findings'. International Journal of Behavioral Nutrition and Physical Activity, 14 (1).
	2018	De Craemer M.;Chastin S.;Ahrens W.;Bernaards C.;Brug J.;Buck C.;Cardon G.;Capranica L.;Dargent-Molina P.;De Lepeleere S.;Hoffmann B.;Kennedy A.;Lakerveld J.;Lien N.;Ling F.;Loyen A.;Macdonncha C.;Nazare J.;O’Donoghue G.;O’Gorman D.;Perchoux C.;Pigeot I.;Simon C.;Mueller-Stierlin A.;van der Ploeg H.;Van Cauwenberg J.;Oppert J. (2018) 'Data on determinants are needed to curb the sedentary epidemic in europe. Lessons learnt from the dedipac european knowledge hub'. International Journal of Environmental Research and Public Health, 15 (7).
	2019	Pastorino S.;Bishop T.;Crozier S.;Granström C.;Kordas K.;Küpers L.;O'Brien E.;Polanska K.;Sauder K.;Zafarmand M.;Wilson R.;Agyemang C.;Burton P.;Cooper C.;Corpeleijn E.;Dabelea D.;Hanke W.;Inskip H.;McAuliffe F.;Olsen S.;Vrijkotte T.;Brage S.;Kennedy A.;O'Gorman D.;Scherer P.;Wijndaele K.;Wareham N.;Desoye G.;Ong K. (2019) 'Associations between maternal physical activity in early and late pregnancy and offspring birth size: remote federated individual level meta-analysis from eight cohort studies'. BJOG: An International Journal of Obstetrics and Gynaecology, .
	2019	Brioche T.;Crampes F.;de Glisezinski I.;Lefai E.;Bareille M.;Chopard A.;Drai J.;Collin-Chavagnac D.;Heer M.;Gauquelin-Koch G.;Prost M.;Simon P.;Py G.;Blanc S.;Simon C.;Bergouignan A.;O'Gorman D. (2019) 'A nutrient cocktail prevents lipid metabolism alterations induced by 20 days of daily steps reduction and fructose overfeeding: result from a randomized study'. Journal of Applied Physiology, 126 (1):88-101.
	2017	Johannes Brug, Hidde P. van der Ploeg, Anne Loyen, Wolfgang Ahrens, Oliver Allais, Lene F. Andersen, Greet Cardon, Laura Capranica, Sebastien Chastin, Ilse De Bourdeaudhuij, Marieke De Craemer, Alan Donnelly, Ulf Ekelund, Paul Finglas, Marion Flechtner-Mors, Antje Hebestreit, Thomas Kubiak, Massimo Lanza, Nanna Lien, Ciaran MacDonncha, Mario Mazzocchi, Pablo Monsivais, Marie Murphy, Mary Nicolaou, Ute Nöthlings, Donal J. O’Gorman, Britta Renner, Gun Roos, Matthijs van den Berg, Matthias B. Schulze, Jürgen M. Steinacker, Karien Stronks, Dorothee Volkert, Jeroen LakerveldEmail authorView ORCID ID profile and on behalf of the DEDIPAC consortium (2017) 'Determinants of diet and physical activity (DEDIPAC): a summary of findings'. International Journal of Behavioral Nutrition and Physical Activity, 14 .
	2017	Hennessy E;Rakovac Tisdall A;Murphy N;Carroll A;O'Gorman D;Breen L;Clarke C;Clynes M;Dowling P;Sreenan S; (2017) 'Elevated 12-hydroxyeicosatetraenoic acid (12-HETE) levels in serum of individuals with newly diagnosed Type 1 diabetes'. Diabetic Medicine, 34 (2).
	2016	O'Donoghue G.;Perchoux C.;Mensah K.;Lakerveld J.;Van Der Ploeg H.;Bernaards C.;Chastin S.;Simon C.;O'Gorman D.;Nazare J. (2016) 'A systematic review of correlates of sedentary behaviour in adults aged 18-65 years: A socio-ecological approach'. BMC Public Health, 16 (1).
	2016	Egan, B;Ashley, DT;Kennedy, E;O'Connor, PL;O'Gorman, DJ (2016) 'Higher rate of fat oxidation during rowing compared with cycling ergometer exercise across a range of exercise intensities'. Scandinavian Journal of Medicine and Science in Sports, 26 :630-637.
	2016	Bergouignan, A;Stein, TP;Habold, C;Coxam, V;Gorman, DO;Blanc, S (2016) 'Towards human exploration of space: The THESEUS review series on nutrition and metabolism research priorities'. Microgravity quarterly : MGQ, 2 .
	2017	Glynn N;Kenny H;Quisenberry L;Halsall DJ;Cook P;Kyaw Tun T;McDermott JH;Smith D;Thompson CJ;O'Gorman DJ;Boelen A;Lado-Abeal J;Agha A; (2017) 'The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies'. Clinical Endocrinology, 86 (5):747-754.
	2015	Monedero J.;Lyons E.;O'Gorman D. (2015) 'Interactive video game cycling leads to higher energy expenditure and is more enjoyable than conventional exercise in adults'. PLoS ONE, 10 (3).
	2014	Monedero, J;McDonnell, AC;Keoghan, M;O'Gorman, DJ (2014) 'Modified Active Videogame Play Results in Moderate-Intensity Exercise'. Games For Health Journal, 3 :234-240.
	2014	Lakerveld, J;van der Ploeg, HP;Kroeze, W;Ahrens, W;Allais, O;Andersen, LF;Cardon, G;Capranica, L;Chastin, S;Donnelly, A;Ekelund, U;Finglas, P;Flechtner-Mors, M;Hebestreit, A;Hendriksen, I;Kubiak, T;Lanza, M;Loyen, A;MacDonncha, C;Mazzocchi, M;Monsivais, P;Murphy, M;Nothlings, U;O'Gorman, DJ;Renner, B;Roos, G;Schuit, AJ;Schulze, M;Steinacker, J;Stronks, K;Volkert, D;van't Veer, P;Lien, N;De Bourdeaudhuij, I;Brug, J (2014) 'Towards the integration and development of a cross-European research network and infrastructure: the DEterminants of DIet and Physical ACtivity (DEDIPAC) Knowledge Hub'. International Journal of Behavioral Nutrition and Physical Activity, 11 .
	2009	Woods C.;Nelson N.;O'Gorman D.;Foley E.;Moyna N. (2009) 'The Take PART study (Physical Activity Research for Teenagers): Rationale and methods'. Journal of physical activity & health, 6 (2):170-177.
	2008	O'Driscoll L.;Kenny E.;Mehta J.;Doolan P.;Joyce H.;Gammell P.;Hill A.;O'Daly B.;O'Gorman D.;Clynes M. (2008) 'Feasibility and relevance of global expression profiling of gene transcripts in serum from breast cancer patients using whole genome microarrays and quantitative RT-PCR'. Cancer Genomics and Proteomics, 5 (2):95-104.
	2007	Brady S.;Carson B.;O'Gorman D.;Moyna N.;Diamond D. (2007) 'Body sensor network based on soft polymer sensors and wireless communications'. Journal of Communications, 2 (5):1-6.
	2015	Kelly P.;Breen L.;Gallagher C.;Kelly S.;Henry M.;Lao N.;Meleady P.;O'Gorman D.;Clynes M.;Barron N. (2015) 'Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype'. Biotechnology journal, 10 (7):1029-1040.
	2015	O'Donoghue G.;Kennedy A.;Stig Andersen G.;Durkan E.;Thybo T.;Sinnott M.;Nolan J.;O'Gorman D. (2015) 'An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: Study protocol for a randomised controlled trial'. Trials, 16 (1).
	2015	Davenport C.;Ashley D.;O'Sullivan E.;McHenry C.;Agha A.;Thompson C.;O'Gorman D.;Smith D. (2015) 'The effects of atorvastatin on arterial stiffness in male patients with type 2 diabetes'. Journal of Diabetes Research, 2015 .
	2014	Andersen G.;Thybo T.;Cederberg H.;Orešič M.;Esteller M.;Zorzano A.;Carr B.;Walker M.;Cobb J.;Clissmann C.;O'Gorman D.;Nolan J. (2014) 'The DEXLIFE study methods: Identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals'. Diabetes Research and Clinical Practice, 106 (2):383-389.
	2013	O'Sullivan E.;Ashley D.;Davenport C.;Penugonda L.;Kelleher G.;Devlin N.;Crowley R.;O'Shea P.;Agha A.;Thompson C.;O'Gorman D.;Smith D. (2013) 'A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance'. Metabolism: Clinical and Experimental, 62 (1):34-38.
	2013	Egan B.;O'Connor P.;Zierath J.;O'Gorman D. (2013) 'Time Course Analysis Reveals Gene-Specific Transcript and Protein Kinetics of Adaptation to Short-Term Aerobic Exercise Training in Human Skeletal Muscle'. PLoS ONE, 8 (9).
	2012	Iglesias-Gutiérrez E.;Egan B.;Díaz-Martínez A.;Peñalvo J.;González-Medina A.;Martínez-Camblor P.;O'Gorman D.;Úbeda N. (2012) 'Transient Increase in Homocysteine but Not Hyperhomocysteinemia during Acute Exercise at Different Intensities in Sedentary Individuals'. PLoS ONE, 7 (12).
	2012	Davenport C.;Kenny H.;Ashley D.;O'Sullivan E.;Smith D.;O'Gorman D. (2012) 'The effect of exercise on osteoprotegerin and TNF-related apoptosis-inducing ligand in obese patients'. European Journal of Clinical Investigation, 42 (11):1173-1179.
	2012	Barrès R.;Yan J.;Egan B.;Treebak J.;Rasmussen M.;Fritz T.;Caidahl K.;Krook A.;O'Gorman D.;Zierath J. (2012) 'Acute exercise remodels promoter methylation in human skeletal muscle'. Cell Metabolism, 15 (3):405-411.
	2012	Harrison M, Moyna NM, Zderic TW, O'Gorman DJ, McCaffrey N, Carson BP, Hamilton MT (2012) 'Lipoprotein Particle Distribution and Skeletal Muscle Lipoprotein Lipase Activity after Acute Exercise'. Lipids in Health and Disease, 11 .
	2011	Egan B, Dowling P, O'Connor PL, Henry M, Meleady P, Zierath JR, O'Gorman DJ (2011) '2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training'. Proteomics, 11 (8):1413-1428.
	2011	Ashley D.;O'Sullivan E.;Davenport C.;Devlin N.;Crowley R.;McCaffrey N.;Moyna N.;Smith D.;O'Gorman D. (2011) 'Similar to adiponectin, serum levels of osteoprotegerin are associated with obesity in healthy subjects'. Metabolism: Clinical and Experimental, 60 (7):994-1000.
	2011	Davenport C.;Ashley D.;O'Sullivan E.;Corley B.;Fitzgerald P.;Agha A.;Thompson C.;O'Gorman D.;Smith D. (2011) 'Identifying coronary artery disease in men with type 2 diabetes: Osteoprotegerin, pulse wave velocity, and other biomarkers of cardiovascular risk'. Journal of Hypertension, 29 (12):2469-2475.
	2011	Cooper D and O’Gorman DJ. (2011) 'Exercise training has diverse responses in patients with type 2 diabetes. DIABETES MANAGEMENT'. 1 :575-587.
	2011	O'Gorman DJ, Krook A (2011) 'Exercise and the treatment of diabetes and obesity. MEDICAL CLINICS OF NORTH AMERICA'. 95 :953-969.
	2010	O’Sullivan EP, Ashley DT, Davenport C, Devlin N, Crowley R, Agha A, Thompson CJ, O’Gorman DJ, Smith D (2010) 'Elevated osteoprotegerin in Type 2 Diabetes may reflect a different underlying process to traditional inflammatory markers. Diabetes/Metabolism Research and Reviews'. .
	2010	Coyle S, Lau K-T, Moyna N, O’Gorman D, Diamond D, Di Francesco F, Costanzo D, Salvo P, Trivella MG, De Rossi DE, Taccini N, Paradiso R, Porchet J-A, Ridolfi A, Luprano J, Chuzel C, Lanier T, Revol-Cavalier F, Schoumacker S, Mourier V, Chartier I, Convert R, De-Moncuit H, Bini C. (2010) 'BIOTEX: Biosensing Textiles for Personalised Healthcare Management. IEEE Transactions on Information Technology in Biomedicine'. 14 :364-370.
	2010	Alsaraj F, O'Gorman D, McAteer S, McDermott J, Hawi Z, Sreenan S (2010) 'Haplotype Association of Calpain 10 Gene Variants with Type 2 Diabetes Mellitus in an Irish Sample'. Irish Journal of Medical Science, 179 :269-272.
	2010	Walls R.;McHugh G.;O'Gorman D.;Moyna N.;O'Byrne J. (2010) 'Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study'. BMC Musculoskeletal Disorders, 11 .
	2010	O'Sullivan E.;Ashley D.;Davenport C.;Devlin N.;Crowley R.;Agha A.;Thompson C.;O'Gorman D.;Smith D. (2010) 'Osteoprotegerin and biomarkers of vascular inflammation in type 2 diabetes'. Diabetes/Metabolism Research and Reviews, 26 (6):496-502.
	2010	Coyle S.;Lau K.;Moyna N.;O'Gorman D.;Diamond D.;Di Francesco F.;Costanzo D.;Salvo P.;Trivella M.;De Rossi D.;Taccini N.;Paradiso R.;Porchet J.;Ridolfi A.;Luprano J.;Chuzel C.;Lanier T.;Revol-Cavalier F.;Schoumacker S.;Mourier V.;Chartier I.;Convert R.;De-Moncuit H.;Bini C. (2010) 'BIOTEXBiosensing textiles for personalised healthcare management'. IEEE Transactions on Information Technology in Biomedicine, 14 (2):364-370.
	2010	Alsaraj F.;O'Gorman D.;McAteer S.;McDermott J.;Hawi Z.;Sreenan S. (2010) 'Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample'. Irish Journal of Medical Science, 179 (2):269-272.
	2010	O'Sullivan E.;Ashley D.;Davenport C.;Kelly J.;Devlin N.;Crowley R.;Leahy A.;Kelly C.;Agha A.;Thompson C.;O'Gorman D.;Fitzgerald P.;Smith D. (2010) 'Osteoprotegerin is higher in peripheral arterial disease regardless of glycaemic status'. Thrombosis Research, 126 (6):e423-e427.
	2010	Egan B.;Carson B.;Garcia-Roves P.;Chibalin A.;Sarsfield F.;Barron N.;McCaffrey N.;Moyna N.;Zierath J.;O'Gorman D. (2010) 'Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle'. Journal of Physiology, 588 (10):1779-1790.
	2010	O’Sullivan EP, Ashley DT, Davenport C, Kelly J, Devlin N, Crowley R, Leahy AL, Kelly CJ, Agha A, Thompson CJ, O’Gorman DJ, Fitzgerald P, Smith D. (2010) 'Osteoprotegerin is higher in peripheral arterial disease regardless of glycaemic status'. Thrombosis Research, 126 :423-427.
	2010	Walls RJ, McHugh G, O’Gorman DJ, Moyna NM, O’Byrne JM (2010) 'Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study'. BMC Musculoskeletal Disorders, 11 :119-127.
	2009	Connaghan D, Hughes S, May G, Kelly P, O’Conaire C, O’Connor NE, O’Gorman DJ, Smeaton AF, Moyna N. (2009) 'A Sensing Platform for Physiological and Contextual Feedback to Tennis Athletes IEEE Wearable and Implantaable Body Sensor Network'. :224-229.
	2009	Woods CB, Nelson NM, O'Gorman DJ, Foley E, Moyna NM (2009) 'The Take PART study (Physical Activity Research for Teenagers): rationale and methods. Journal of Physical Activity and Health'. 6 :170-177.
	2009	Harrison M, O’Gorman DJ, McCaffrey N, Hamilton MT, Zderic TW, Carson BP, Moyna NM (2009) 'Influence of acute exercise with and without carbohydrate replacement on postprandial lipid metabolism'. Journal of Applied Physiology, 106 :943-949.
	2009	MacEneaney OJ, Harrison M, O’Gorman DJ, Pankratieva EV, O’Connor PL, Moyna NM (2009) 'Effect of prior exercise on postprandial lipemia and markers of inflammation and endothelial activation in normal weight and overweight adolescent boys'. European Journal of Applied Physiology, 106 :721-729.
	2009	Harrison M, Murphy RP, O'Connor PL, O'Gorman DJ, McCaffrey N, Cummins PM, Moyna NM (2009) 'The endothelial microparticle response to a high fat meal is not attenuated by prior exercise'. European Journal of Applied Physiology, 106 :555-562.
	2008	O’Gorman DJ and Krook A. (2008) 'Exercise and the treatment of diabetes and obesity. Endocrinology and Metabolism Clinics of North America'. 37 :887-903.
	2008	Nelson NM, Foley E, O’Gorman DJ, Moyna NM, Woods CB (2008) 'Active commuting to school: How far is too far?'. International Journal of Behavioral Nutrition and Physical Activity, 5 :1-9.
	2008	O'Driscoll L, Kenny E, Mehta JP, Doolan P, Joyce H, Gammell P, Hill A, O'Daly B, O'Gorman DJ and Clynes M. (2008) 'Feasibility and relevance of global expression profiling of gene transcripts in serum from breast cancer patients using whole genome microarrays and quantitative RT-PCR'. Cancer Genomics and Proteomics, 5 :95-104.
	2008	O’Gorman DJ, Yousif O, Dixon G, McQuaid S, Murphy E, Rahman Y, Gasparro D, Pacini G, Newsholme P,Nolan JJ. (2008) 'In vivo and in vitro studies of GAD-antibody positive subjects with Type 2 diabetes: a distinct sub-phenotype. Diabetes Research and Clinical Practice'. 80 :365-370.
	2008	Woods, C.B., Nelson, N., Foley, E., O’Gorman, D. and Moyna, N. (2008) 'Take PART Study: Rationale and Methodology'. 1 :1-28.
	2007	Brady S, Carson B, O'Gorman DJ, Moyna N, Diamond, D (2007) 'Combining wireless with wearable technology for the development of on-body networks. Journal of Communications'. 2 :1-6.
	2006	O’Gorman DJ, Karlsson HKR, McQuaid S, Yousif O, Rahman Y, Gasparro D, Glund S, Chibalin AV, Zierath JR, Nolan JJ (2006) 'Exercise training increases insulin-stimulated glucose disposal and GLUT-4 protein content in patients with Type 2 diabetes'. Diabetologia, 49 :2983-2992.
	2005	McQuaid S, O’Gorman DJ, Yousif, O, Yeow T.-P, Rahman Y, Gasparro D, Pacini G, Nolan JJ. (2005) 'Early Onset Insulin Resistant Diabetes in Obese Caucasians has Features of Typical Type 2 Diabetes, but Three Decades Earlier'. Diabetes Care, Diabetes Care 28 :1216-1218.
	2001	Kirwan, J.P., D.J. O'Gorman, D. Cyr-Campbell, W.W. Campbell, K.E. Yarasheki, and W.J. Evans (2001) 'Effects of a moderate glycemic meal on exercise duration and substrate utilization'. 33(9) :1517-1523.
	2000	O'Gorman, D.J.. A. Hunter, C. McDonnacha, and J.P. Kirwan (2000) 'Validity of field tests to evaluate endurance capacity in competitive and international level sports participants'. Journal of Strength and Conditioning Research, 14(1) :62-67.
	2000	O'Gorman, D.J., L.F. del Aguila, D. L. Williamson, R.K. Krishnan, and J.P. Kirwan (2000) 'Insulin and Exercise Differentially Regulate IRS-1-Associated PI3-Kinase and Glycogen Synthase in Human Skeletal Muscle During Immediate Recovery from Exercise'. Journal of Applied Physiology, 89 :1412-1419.
	2000	Kirwan, J.P., L.F. del Aguila, D.L. Williamson, D.J. O'Gorman, R.M. Lewis, and R.K. Krishnan (2000) 'Regular exercise enhances insulin activation of IRS-1 associated PI 3-kinase in human skeletal muscle'. Journal of Applied Physiology, 88 :797-803.
	1998	Krishnan, R.K., J.M. Hernandez, D.L. Williamson, D.J. O'Gorman, W.J. Evans, and J.P. Kirwan (1998) 'Age-related differences in the pancreatic B-cell response to hyperglycemia after eccentric exercise'. American Journal of Physiology, 275(5) :E463-E470.
	1998	Kirwan, J.P., D.J. O'Gorman, and W.J. Evans. (1998) 'A moderate glycemic meal prior to endurance exercise can enhance performance'. 84(1) :53-59.

Research Interests

Skeletal muscle contraction as a regulator of gene transcription and protein content Muscle contraction is an important stimulus of gene transcription and it is known that in trained individuals across all age groups, the number of mitochondria and the content of key regulators of metabolism are increased. We are looking at the role of contraction intensity on the regulation of gene transcription. Insulin and non-insulin mediated glucose transport The evaluation of insulin-mediated signalling pathways is central to our understanding of glucose transport. We also use the model of muscular contraction to elicit improvements in GLUT-4 translocation and subsequent improvements in metabolic function. This model is useful for the study of insulin and non-insulin mediated pathways of glucose transport and especially useful in the identification of novel pathways that may become pharmacological targets. Cellular and molecular regulation of substrate utilisation The regulation of energy expenditure, especially glucose-free fatty acid cycling in skeletal muscle, contributes to the progressive decrease in insulin sensitivity.