CARAMEL
Dr Louise Hopper will lead the university's contribution to the project CARAMEL
Women’s cardiovascular health is an urgent clinical unmet need as cardiovascular disease (CVD) risk in women is under-diagnosed, under-treated and poorly understood, more so in women in the 40-60 age group, when personalised risk assessment and prevention can have a positive health impact. This research programme, CARAMEL, will deliver an innovative personalised prevention model aimed at women 40-60yrs based upon a risk assessment stratification model considering sex and gender specific risk factors and a self-assessment and self-management approach using innovative digital technologies, empowering women to optimise their cardiovascular health.
The proposed CVD-Risk Assessment and Stratification scheme will only be possible by the cumulative risk factors analysis, fueled by AI, emerging from a wide number of data sources (EHR clinical data, medical imaging, biomarkers, metabolomics, and lifestyle from large cohorts and biobanks). A consortium of 25 partners (11 countries, 9 clinical, 6 research, 10 industry/SMEs) will develop, test and validate the personalised prevention program in observational and interventional studies in five clinical sites. Women aged 40-60 will engage from the onset of CARAMEL on the co-design of the studies and the self-management app ecosystem to be developed.
DCU Project lead:
Dr Louise Hopper.