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Entwine’s mission is to design a scalable infrastructure to support the Internet of Things and its applications. Existing solutions for machine-to-machine communication and for intermediation between sensors, actuators and other devices, and the associated data analysis and control algorithms, do not scale to the size needed by, for example, a smart city. Centre researchers will design the necessary framework to deliver solutions of this scale. This framework will support autonomous operation, so that the Internet of Things can be managed by the Things themselves.