Developing effective interventions to counter misinformation is an urgent goal, but it also presents conceptual, empirical, and practical difficulties, compounded by the fact that misinformation research is in its infancy. This paper provides researchers and policymakers with an overview of which individual-level interventions are likely to influence the spread of, susceptibility to, or impact of misinformation. We review the evidence for the effectiveness of four categories of interventions: boosting (psychological inoculation, critical thinking, and media and information literacy); nudging (accuracy primes and social norms nudges); debunking (fact-checking); and automated content labeling. In each area, we assess the empirical evidence, key gaps in knowledge, and practical considerations. We conclude with a series of recommendations for policymakers and tech companies to ensure a comprehensive approach to tackling misinformation.