David Kinahan

Assist. Prof

Contact Details

Biography

David Kinahan is an Assistant Professor in the School of Mechanical and Manufacturing Engineering since October 2018. David completed a BEng in Aeronautical Engineering (2003) and a PhD (2008) at University of Limerick (UL). His PhD focused on high-throughput droplet microfluidics for DNA analysis. In late 2007 David joined Stokes Bio Ltd, a spin-out from UL, as a Senior Engineer, and was later promoted to Engineering Manager leading a team of 10 engineers. In January 2012 David joined the Biomedical Diagnostics Institute  in DCU and since then has applied microfluidics to a wide range of application areas including human health (HIV diagnostics, CTC detection, CVD diagnostics, liver disease, early detection of bacterial meningitis) and point-of-use testing (plant pathogen detection, environmental monitoring etc). From January 2017 until October 2018 David was a Group Leader within Fraunhofer Project Center at Dublin City University (FPC@DCU).

Book Chapters

  Year Publication
2016 'The centrifugal microfluidic: Lab-on-a-disc platform'
Henderson B.;Kinahan D.;Ducrée J. (2016) 'The centrifugal microfluidic: Lab-on-a-disc platform' In: Microfluidics for Biologists: Fundamentals and Applications. [DOI] [Details]
2016 'Lumped-Element Modeling for Rapid Design and Simulation of Digital Centrifugal Microfluidic Systems'
Mohammadi, Mahdi and Kinahan, David J and Ducr\'ee, Jens (2016) 'Lumped-Element Modeling for Rapid Design and Simulation of Digital Centrifugal Microfluidic Systems' In: Lab-on-a-Chip: Fabrication and Application. xx: InTech. [Details]
2015 'Centrifugal Flow Control'
Nwankire, Charles E and Kinahan, David J and Ducr{\'e}e, Jens (2015) 'Centrifugal Flow Control' In: Encyclopedia of Microfluidics and Nanofluidics. New York: Springer. [Details]
2015 'Microfluidic Cell Enumeration for Biomedical Diagnostics'
Kinahan, David J and Glynn, Macdara T and Ducr{\'e}e, Jens (2015) 'Microfluidic Cell Enumeration for Biomedical Diagnostics' In: Encyclopedia of Microfluidics and Nanofluidics. New York: Spring. [Details]
2014 'Functional Membranes for Enhanced Rotational Flow Control on Centrifugal Microfluidic Platforms'
Mishra, R and Gaughran, J and Kinahan, D and Ducr{\'e}e, J (2014) 'Functional Membranes for Enhanced Rotational Flow Control on Centrifugal Microfluidic Platforms' In: Reference Module in Materials Science and Materials Engineering. Elsevier: Elsevier. [Details]

Peer Reviewed Journals

  Year Publication
2020 'Siphon-Induced Droplet Break-Off for Enhanced Mixing on a Centrifugal Platform'
Robert Burger ,David J Kinahan ,Hélène Cayron ,Nuno Reis ,João Fonseca andJens Ducrée (2020) 'Siphon-Induced Droplet Break-Off for Enhanced Mixing on a Centrifugal Platform'. Inventions, [Details]
2018 'A 3D-printed optical reader and wall projector for enumeration of CD4 cells in resource-limited point-of-care settings'
Macdara T. Glynn and David J. Kinahan and Niamh A. McArdle and Jane L. Kendlin and Tr\'\iona M. O'Connell and Jens Ducrée (2018) 'A 3D-printed optical reader and wall projector for enumeration of CD4 cells in resource-limited point-of-care settings'. PLoS ONE, [Details]
2018 'Label-free, spatially multiplexed SPR detection of immunoassays on a highly integrated centrifugal Lab-on-a-Disc platform'
Miyazaki C.;Kinahan D.;Mishra R.;Mangwanya F.;Kilcawley N.;Ferreira M.;Ducrée J. (2018) 'Label-free, spatially multiplexed SPR detection of immunoassays on a highly integrated centrifugal Lab-on-a-Disc platform'. Biosensors and Bioelectronics, 119 :86-93 [DOI] [Details]
2018 'Wirelessly powered and remotely controlled valve-array for highly multiplexed analytical assay automation on a centrifugal microfluidic platform'
Delgado, Saraí M Torres,Kinahan, David J,Julius, Lourdes Albina Nirupa,Mallette, Adam,Ardila, David Sáenz,Mishra, Rohit,Miyazaki, Celina M,Korvink, Jan G,Ducrée, Jens,Mager, Dario (2018) 'Wirelessly powered and remotely controlled valve-array for highly multiplexed analytical assay automation on a centrifugal microfluidic platform'. Biosensors and Bioelectronics, 109 :214-223 [Details]
2017 'Development of an on-disc isothermal in vitro amplification and detection of bacterial RNA'
Brennan, Des,Coughlan, Helena,Clancy, Eoin,Dimov, Nikolay,Barry, Thomas,Kinahan, David,Ducrée, Jens,Smith, Terry J,Galvin, Paul (2017) 'Development of an on-disc isothermal in vitro amplification and detection of bacterial RNA'. Sensors and Actuators B: Chemical, 239 :235-242 [Details]
2017 'Polyethylene imine/graphene oxide layer-by-layer surface functionalization for significantly improved limit of detection and binding kinetics for immunoassays on acrylate surfaces'
Celina M. Miyazaki and Rohit Mishra and David J. Kinahan and Marystela Ferreira and Jens Ducr\'ee (2017) 'Polyethylene imine/graphene oxide layer-by-layer surface functionalization for significantly improved limit of detection and binding kinetics for immunoassays on acrylate surfaces'. Colloids and Surfaces B: Biointerfaces, 158 :167-174 [DOI] [Details]
2016 'Baking powder actuated centrifugo-pneumatic valving for automation of multi-step bioassays'
David J. Kinahan and Marine Renou and Dirk Kurzbuch and Niamh A. Kilcawley and \'Eanna Bailey and Macdara T. Glynn and Collette McDonagh and Jens Ducr\'ee (2016) 'Baking powder actuated centrifugo-pneumatic valving for automation of multi-step bioassays'. Micromachines, 7 (10):175-184 [DOI] [Details]
2016 'Xurography actuated valving for centrifugal flow control'
David J. Kinahan and Philip L. Early and Abhishek Vembadi and Eoghan MacNamara and Niamh A. Kilcawley and Thomas Glennon and Dermot Diamond and Dermot Brabazon and Jens Ducr\'ee (2016) 'Xurography actuated valving for centrifugal flow control'. Lab on a Chip, 16 (18):3454-3459 [DOI] [Details]
2016 'Fully automated chemiluminescence detection using the electrified-Lab-on-a-Disc (eLoaD) platform'
Saraí M. Torres Delgado and David J. Kinahan and Fralett Su\'arez Sandoval and Lourdes A.N. Julius and Niamh A. Kilcawley and Jens Ducr\'ee and Dario Mager (2016) 'Fully automated chemiluminescence detection using the electrified-Lab-on-a-Disc (eLoaD) platform'. Lab on a Chip, 16 (20):4002-4011 [DOI] [Details]
2016 'Density-gradient mediated band extraction of leukocytes from whole blood using centrifugo-pneumatic siphon valving on centrifugal microfluidic discs'
Kinahan, David J,Kearney, Sinéad M,Kilcawley, Niamh A,Early, Philip L,Glynn, Macdara T,Ducrée, Jens (2016) 'Density-gradient mediated band extraction of leukocytes from whole blood using centrifugo-pneumatic siphon valving on centrifugal microfluidic discs'. PloS one, 11 (5) [Details]
2016 'CD-based microfluidics for primary care in extreme point-of-care settings'
Smith, Suzanne,Mager, Dario,Perebikovsky, Alexandra,Shamloo, Ehsan,Kinahan, David,Mishra, Rohit,Torres Delgado, Saraí M,Kido, Horacio,Saha, Satadal,Ducrée, Jens (2016) 'CD-based microfluidics for primary care in extreme point-of-care settings'. Micromachines, 7 (2) [Details]
2015 'Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms'
Kinahan, David J,Kearney, Sinéad M,Faneuil, Olivier P,Glynn, Macdara T,Dimov, Nikolay,Ducrée, Jens (2015) 'Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms'. RSC Advances, 5 (3):1818-1826 [Details]
2015 'Cluster size distribution of cancer cells in blood using stopped-flow centrifugation along scale-matched gaps of a radially inclined rail'
Macdara Glynn, Charles Nwankire, Kate Lemass, David J Kinahan, Jens Ducrée (2015) 'Cluster size distribution of cancer cells in blood using stopped-flow centrifugation along scale-matched gaps of a radially inclined rail'. Microsystems & Nanoengineering, [Details]
2014 'Event-triggered logical flow control for comprehensive process integration of multi-step assays on centrifugal microfluidic platforms'
Kinahan, David J,Kearney, Sinéad M,Dimov, Nikolay,Glynn, Macdara T,Ducrée, Jens (2014) 'Event-triggered logical flow control for comprehensive process integration of multi-step assays on centrifugal microfluidic platforms'. Lab on a Chip, 14 (13):2249-2258 [Details]
2014 'Spira mirabilis enhanced whole blood processing in a lab-on-a-disk'
Kinahan, David J,Kearney, Sinéad M,Glynn, Macdara T,Ducrée, Jens (2014) 'Spira mirabilis enhanced whole blood processing in a lab-on-a-disk'. Sensors and Actuators A: Physical, 215 :71-76 [Details]
2014 'Rapid, low-cost and instrument-free CD4+ cell counting for HIV diagnostics in resource-poor settings'
Glynn, Macdara T,Kinahan, David J,Ducrée, Jens (2014) 'Rapid, low-cost and instrument-free CD4+ cell counting for HIV diagnostics in resource-poor settings'. Lab on a Chip, 14 (15):2844-2851 [Details]
2014 'Centrifugo-magnetophoretic purification of CD4+ cells from whole blood toward future HIV/AIDS point-of-care applications'
Glynn, Macdara,Kirby, Daniel,Chung, Danielle,Kinahan, David J,Kijanka, Gregor,Ducrée, Jens (2014) 'Centrifugo-magnetophoretic purification of CD4+ cells from whole blood toward future HIV/AIDS point-of-care applications'. Journal of laboratory automation, 19 (3):285-296 [Details]
2013 'CD4 counting technologies for HIV therapy monitoring in resource-poor settings–state-of-the-art and emerging microtechnologies'
Glynn, Macdara T,Kinahan, David J,Ducrée, Jens (2013) 'CD4 counting technologies for HIV therapy monitoring in resource-poor settings–state-of-the-art and emerging microtechnologies'. Lab on a Chip, 13 (14):2731-2748 [Details]
2012 'Centrifugal microfluidics for cell analysis'
Burger, Robert,Kirby, Daniel,Glynn, Macdara,Nwankire, Charles,O'Sullivan, Mary,Siegrist, Jonathan,Kinahan, David,Aguirre, Gerson,Kijanka, Gregor,Gorkin III, Robert A (2012) 'Centrifugal microfluidics for cell analysis'. Current opinion in chemical biology, 16 (3-4):409-414 [Details]
2009 'Measurement of substrate thermal resistance using DNA denaturation temperature'
David Kinahan , Tara Dalton , Mark Davies (2009) 'Measurement of substrate thermal resistance using DNA denaturation temperature'. INTERNATIONAL JOURNAL OF THERMAL SCIENCES, 49 :333-339 [Details]
2009 'Effect of substrate thermal resistance on space-domain microchannel'
David J. Kinahan , Tara M. Dalton , Mark RD. Davies (2009) 'Effect of substrate thermal resistance on space-domain microchannel'. BIOMEDICAL MICRODEVICES, 11 :747-754 [Details]

Conference Publications

  Year Publication
2019 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND
Sriram Thoppe Rajendran, Khorshid Kamguyan, David Kinahan, En-Te Hwu, Line Hagner Nielsen, Kinga Zór, and Anja Boisen (2019) Artificial Gut-on-a-Disc Platform to Evaluate PH Sensitive Coating for Oral Drug Delivery Devices 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND [Details]
2019 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND
Eimear Higgins, Cian Merne, Patrick Wogan, David Collins, Sarai M. Torres-Delgado, Dario Mager and David J. Kinahan (2019) Differential Second Degree of Freedom Centrifugal Microfluidics 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND [Details]
2018 Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Berger M.;Müller T.;Voebel T.;Baum C.;Glennon T.;Mishra R.;Kinahan D.;King D.;Ducrée J.;Brecher C. (2018) Automated assembly of microfluidic lab-on-A-disc Progress in Biomedical Optics and Imaging - Proceedings of SPIE [DOI] [Details]
2018 Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Kinahan D.;Delgado S.;Julius L.;Mallette A.;Saenz-Ardila D.;Mishra R.;Miyazaki C.;Korvink J.;Mager D.;Ducree J. (2018) Wireless closed-loop control of centrifugo-pneumatic valving towards large-scale microfluidic process integration Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) , pp.1213-1216 [DOI] [Details]
2018 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
Brennan D.;Coughla H.;Clancy E.;Dimov N.;Barry T.;Kinahan D.;Ducree J.;Smith T.;Galvin P. (2018) Development of a system for on-disc isothermal in vitro amplification and detection of bacterial RNA 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings , pp.1-4 [DOI] [Details]
2017 Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2017), October 22--26, Savannah, Georgia, USA
Celina Miyazaki and David J. Kinahan and Rohit Mishra and Marystela Ferreira and Jens Ducr\'ee (2017) Immunosensing by centrifugally automated surface-plasmon resonance detection based on a smartphone camera . In: Abraham Lee and Don DeVoe eds. Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2017), October 22--26, Savannah, Georgia, USA [Details]
2016 Proceedings of the 11$^\rm th$ Rapid Methods Europe on Food, Feed and Water Analysis (RME 2016) held in Amsterdam, The Netherlands, 7 -- 9 November
David J. Kinahan and Danielle Chung and Jens Ducr\'ee (2016) An automated centrifugal microfluidic platform for on-site applications Proceedings of the 11$^\rm th$ Rapid Methods Europe on Food, Feed and Water Analysis (RME 2016) held in Amsterdam, The Netherlands, 7 -- 9 November [Details]
2016 Proceedings of the 27th Micromechanics and Microsystems Europe Workshop (MME 2016) in Cork, Ireland, August 28-30
David J. Kinahan and Faith Mangwanya and Robert Garvey and Danielle W. Y. Chung and Artur Lipinski and Lourdes A. N. Julius and Damien King and Rohit Mishra and Mehdi Mohammadi and May Al-Ofi and Celina Miyazaki and Jens Ducr\'ee (2016) Automation of silica bead-based nucleic acid extraction on a centrifugal Lab-on-a-Disc platform Proceedings of the 27th Micromechanics and Microsystems Europe Workshop (MME 2016) in Cork, Ireland, August 28-30 [Details]
2016 Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland
Sara\'\i M. Torres Delgado and David J. Kinahan and Niamh A. Kilcawley and Lourdes A. N. Julius and Brian Henderson and Jan G. Korvink and Jens Ducr\'ee and Dario Mager (2016) A fully automated wirelessly powered centrifugal platform towards a sample-to-answer chemiluminescent ELISA assay for CVD detection . In: Nicole Pamme and Jens Ducr\'ee eds. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland , pp.1348-1349 [Details]
2016 Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland
Mahdi Mohammadi and David J. Kinahan and Jens Ducr\'ee (2016) Lumped element simulation of a highly integrated bioanalytical centrifugal processing unit (\lq\lq BioCPU) . In: Nicole Pamme and Jens Ducr\'ee eds. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland , pp.784-785 [Details]
2016 Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland
David J. Kinahan and Kate McConville and Brian Henderson and Margaret McCaul and Eoghan McNamara and Dermot Diamond and Jens Ducr\'ee (2016) Digital pulse actuated flow control on a centrifugal disc towards multiparameter water quality monitoring . In: Nicole Pamme and Jens Ducr\'ee eds. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland , pp.871-872 [Details]
2016 Proceedings of the 26th Anniversary World Congress on Biosensors (Biosensors 2016), Swedish Exhibition and Congress Centre, Gothenburg, Sweden, May 25--27
Brian Henderson and David J. Kinahan and Jeanne Rio and Rohit Mishra and Damien King and Sarai Torres-Delgado and Dario Mager and Jan Korvink and Jens Ducr\'ee (2016) Timing of a centrifugally automated, multi-step chemiluminescent CRP assay towards a point-of-care for early-stage detection of cardiovascular disease . In: Anthony P. F. Turner eds. Proceedings of the 26th Anniversary World Congress on Biosensors (Biosensors 2016), Swedish Exhibition and Congress Centre, Gothenburg, Sweden, May 25--27 [Details]
2015 Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2015), October 25--29, Gyeongju City, Korea
Macdara T. Glynn and Jane L. Kendlin and David J. Kinahan and Jens Ducr\'ee (2015) A 3D-printed optical reader for cost-efficient enumeration of CD4 cells for point-of-care diagnostics of HIV in resource-poor settings . In: Je-Kyun Park eds. Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2015), October 25--29, Gyeongju City, Korea , pp.1235-1237 [Details]
2015 Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal
David J. Kinahan and Robert Burger and Abhishek Vembadi and Niamh A. Kilcawley and Daryl Lawlor and Macdara T. Glynn and Jens Ducr\'ee (2015) Baking-powder driven centripetal pumping controlled by event-triggering of functional liquids . In: J\urgen Brugger and Wouter van der Wijngaart eds. Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal , pp.504-507 [Details]
2015 MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Glynn M.;Kendlin J.;Kinahan D.;Ducrée J. (2015) A 3D-printed optical reader for cost-efficient enumeration of cd4 cells for point-of-care diagnostics of HIV in resource-poor settings MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences , pp.1235-1237 [Details]
2015 2015 28TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2015)
Glynn, M;Nwankire, C;Kinahan, D;Ducree, J (2015) CLUSTER SIZING OF CANCER CELLS BY RAIL-BASED SERIAL GAP FILTRATION IN STOPPED-FLOW, CONTINUOUS SEDIMENTATION MODE 2015 28TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2015) , pp.192-195 [Details]
2015 Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Mishra R.;Alam R.;Kinahan D.;Anderson K.;Ducree J. (2015) Lipophilic-membrane based routing for centrifugal automation of heterogeneous immunoassays Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) , pp.523-526 [DOI] [Details]
2015 Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal
Rohit Mishra and Rizwan Alam and David J. Kinahan and Karen Anderson and Jens Ducr\'ee (2015) Lipophilic-membrane based routing for centrifugal automation of heterogeneous immunoassays . In: J\urgen Brugger and Wouter van der Wijngaart eds. Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal , pp.523-525 [Details]
2015 Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal
David J. Kinahan and Robert Burger and Abhishek Vembadi and Niamh A. Kilcawley and Daryl Lawlor and Macdara T. Glynn and Jens Ducr\'ee (2015) Baking-powder driven centripetal pumping controlled by event-triggering of functional liquids . In: J\urgen Brugger and Wouter van der Wijngaart eds. Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal , pp.504-507 [Details]
2015 Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Glynn M.;Nwankire C.;Kinahan D.;Ducree J. (2015) Cluster sizing of cancer cells by rail-based serial gap filtration in stopped-flow, continuous sedimentation mode Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) , pp.192-195 [DOI] [Details]

Committees

  Committee Function From / To
International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS) Technical Program Committee Member 2016 / 2017

Patents

  Patent Number Title
EP2994232B1 Rotatable microfluidic device with dissolvable release valve and control valve

Research Projects

  Title Funder From - To Role Award
Innovation Eco-system to Accelerate the Industrial Uptake of Advanced Surface Nano-Technologies EU Horizon 2020 01-APR-20 - 31-MAR-24 DCU PI 1,209,076.84
Proof-of-Concept PCR Thermocycler with Integrated Microfluidic Liquid Handling Enterprise Ireland 01-MAR-20 - 31-MAY-21 DCU PI 259,687.77
Arraying of Liquids for Medium-Throughput Screening Applications (MxN Chip) Enterprise Ireland 01-MAY-17 - 31-JUL-17 DCU PI 19,028.10

Contract Researchers

  Researcher Name Project Role Funding Body
Brian Hughes MxNCycler Research Assistant
Eadaoin Carthy MxNCycler Postdoctoral Researcher

Current Postgraduate Students

  Student Degree Type Supervision Type
Chekotu , Josiah Cherian PhD-track Supervisor

Modules Coordinated

  Term (ID)) Title Link Subject
2020 Fundamentals of Control MM353Fundamentals of Control
2020 Product Design, Development & Value Analysis MM523Product Design, Development & Value Analysis
2020 Manufacturing Processes 1 MM252Manufacturing Processes 1