Paul Cahill

Prof

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ACADEMIC APPOINTMENTS 2018: Chair of Vascular Biology & Therapeutics Faculty of Science and Health Dublin City University 2015: Full Professor School of Biotechnology Faculty of Science and Health Dublin City University 2002: Director, Vascular Health Research Centre Faculty of Science and Health Dublin City University 2001: Professor School of Biotechnology Dublin City University 2000: Adjunct Professor Department of Surgery and Pharmacology University of Rochester Medical Centre Rochester NY, USA 2000: Wellcome Trust New Blood Fellow School of Biotechnology Dublin City University 1999: Professor Department of Surgery and Pharmacology University of Rochester Medical Centre Rochester NY, USA 1997: Associate Professor Director of Surgical Research Division Department of Surgery and Physiology Georgetown University Medical Centre Washington DC, 20007. 1995: Assistant Professor Department of Surgery and Physiology Georgetown University Medical Centre Washington DC 20007 1992: Instructor - Research Associate Department of Surgery Division of Surgical Oncology Johns Hopkins Medical Institutions Baltimore, MD 21287 1991: Research Fellow Department of Physiology & Biophysics University of Tennessee, Memphis, TN 38163 1990: Research Fellow Department of Pharmacology New York Medical College Valhalla, NY 1059


Book Chapter

Year Publication
2020 O’Connor R.A.; Cahill P.A.; McGuinness G.B. (2020) 'Cardiovascular Tissue Engineering' In: Biomaterials for Organ and Tissue Regeneration. United Kingdom : Woodhead Publishing. Link
2016 Redmond E.;Lally C.;Cahill P. (2016) 'Common Pathways in Cancer, Tumor Angiogenesis and Vascular Disease' In: Cardio-Oncology: Principles, Prevention and Management.
2012 Redmond E.;Lally C.;Cahill P. (2012) 'Hemodynamic control of vascular smooth muscle function' In: Muscle.
2002 Redmond E.;Cahill P. (2002) 'Alcohol, vascular cells and hemodynamic forces' In: Alcohol and Heart Disease.
2010 Guha, S, Walls, D, Redmond EM, Cahill PA. (2010) 'Pathogenetic mechanisms in Alagille syndrome' In: Encyclopedia of Life Sciences. : Wiley.

Peer Reviewed Journal

Year Publication
2021 Molony, C. and King, D. and Di Luca, M. and Kitching, M. and Olayinka, A. and Hakimjavadi, R. and Julius, L.A.N. and Fitzpatrick, E. and Gusti, Y. and Burtenshaw, D. and Healy, K. and Finlay, E.K. and Kernan, D. and Llobera, A. and Liu, W. and Morrow, D. and Redmond, E.M. and Ducrée, J. and Cahill, P.A. (2021) 'Disease-Relevant Single Cell Photonic Signatures Identify S100β Stem Cells and their Myogenic Progeny in Vascular Lesions'. . Link
2021 Di Luca, M. and Fitzpatrick, E. and Burtenshaw, D. and Liu, W. and Helt, J.-C. and Hakimjavadi, R. and Corcoran, E. and Gusti, Y. and Sheridan, D. and Harman, S. and Lally, C. and Redmond, E.M. and Cahill, P.A. (2021) 'The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions'. 6 (1). Link
2020 Burtenshaw, D. and Cahill, P.A. (2020) 'Natriuretic Peptides and the Regulation of Retinal Neovascularization'. 40 (1):7-10. Link
2020 Roberts J;Pritchard AL;Treweeke AT;Rossi AG;Brace N;Cahill P;MacRury SM;Wei J;Megson IL; (2020) 'Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System'. Frontiers In Cardiovascular Medicine, 7 .
2020 Liu W.;Harman S.;DiLuca M.;Burtenshaw D.;Corcoran E.;Cahill P.A.;Redmond E.M. (2020) 'Moderate Alcohol Consumption Targets S100β+ Vascular Stem Cells and Attenuates Injury-Induced Neointimal Hyperplasia'. Alcoholism: Clinical and Experimental Research, .
2020 Mathew, S.A. and Naik, C. and Cahill, P.A. and Bhonde, R.R. (2020) 'Placental mesenchymal stromal cells as an alternative tool for therapeutic angiogenesis'. 77 (2):253-265. Link
2020 Liu, W. and Harman, S. and DiLuca, M. and Burtenshaw, D. and Corcoran, E. and Cahill, P.A. and Redmond, E.M. (2020) 'Moderate Alcohol Consumption Targets S100β+ Vascular Stem Cells and Attenuates Injury-Induced Neointimal Hyperplasia'. 44 (9):1734-1746. Link
2020 Mathieu, P.S. and Fitzpatrick, E. and Di Luca, M. and Cahill, P.A. and Lally, C. (2020) 'Resident multipotent vascular stem cells exhibit amplitude dependent strain avoidance similar to that of vascular smooth muscle cells'. 521 (3):762-768. Link
2019 King D.;Glynn M.;Cindric S.;Kernan D.;O’Connell T.;Hakimjavadi R.;Kearney S.;Ackermann T.;Berbel X.;Llobera A.;Simonsen U.;Laursen B.;Redmond E.;Cahill P.;Ducrée J. (2019) 'Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform'. Scientific Reports, 9 (1).
2019 Burtenshaw, D. and Kitching, M. and Redmond, E.M. and Megson, I.L. and Cahill, P.A. (2019) 'Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease'. 6 . Link
2019 Clarkin, O.M. and Wu, B. and Cahill, P.A. and Brougham, D.F. and Banerjee, D. and Brady, S.A. and Fox, E.K. and Lally, C. (2019) 'Novel injectable gallium-based self-setting glass-alginate hydrogel composite for cardiovascular tissue engineering'. 217 :152-159. Link
2019 Mathieu P.;Fitzpatrick E.;Di Luca M.;Cahill P.;Lally C. (2019) 'Resident multipotent vascular stem cells exhibit amplitude dependent strain avoidance similar to that of vascular smooth muscle cells'. Biochemical and Biophysical Research Communications, .
2019 Burtenshaw D;Kitching M;Redmond EM;Megson IL;Cahill PA; (2019) 'Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease'. Frontiers In Cardiovascular Medicine, 6 .
2019 King, D. and Glynn, M.D. and Cindric, S. and Kernan, D. and O’Connell, T. and Hakimjavadi, R. and Kearney, S. and Ackermann, T. and Berbel, X.M. and Llobera, A. and Simonsen, U. and Laursen, B.E. and Redmond, E.M. and Cahill, P.A. and Ducrée, J. (2019) 'Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform'. 9 (1). Link
2019 Clarkin O.;Wu B.;Cahill P.;Brougham D.;Banerjee D.;Brady S.;Fox E.;Lally C. (2019) 'Novel injectable gallium-based self-setting glass-alginate hydrogel composite for cardiovascular tissue engineering'. Carbohydrate Polymers, 217 :152-159.
2018 Hatch, E;Morrow, D;Liu, WM;Cahill, PA;Redmond, EM (2018) 'Differential effects of alcohol and its metabolite acetaldehyde on vascular smooth muscle cell Notch signaling and growth'. American Journal of Physiology - Heart and Circulatory Physiology, 314 :131-137.
2018 Molony, C. and McIntyre, J. and Maguire, A. and Hakimjavadi, R. and Burtenshaw, D. and Casey, G. and Di Luca, M. and Hennelly, B. and Byrne, H.J. and Cahill, P.A. (2018) 'Label-free discrimination analysis of de-differentiated vascular smooth muscle cells, mesenchymal stem cells and their vascular and osteogenic progeny using vibrational spectroscopy'. 1865 (2):343-353. Link
2018 Molony, C;McIntyre, J;Maguire, A;Hakimjavadi, R;Burtenshaw, D;Casey, G;Di Luca, M;Hennelly, B;Byrne, HJ;Cahill, PA (2018) 'Label-free discrimination analysis of de-differentiated vascular smooth muscle cells, mesenchymal stem cells and their vascular and osteogenic progeny using vibrational spectroscopy'. Biochimica Et Biophysica Acta-Molecular Cell Research, 1865 :343-353.
2017 Burtenshaw, Denise and Hakimjavadi, Roya and Redmond, Eileen M. and Cahill, Paul A. (2017) 'Nox, Reactive Oxygen Species and Regulation of Vascular Cell Fate'. 6 (4).
2017 Liu, W. and Fitzpatrick, E. and Cahill, P. A. and Redmond, E. M. (2017) 'DAILY MODERATE ALCOHOL CONSUMPTION INHIBITS SCA1+ADVENTITIAL PROGENITOR CELL EXPANSION AND CAROTID REMODELING; ROLE OF HEDGEHOG SIGNALING'. 41 (1, SI).
2017 Fitzpatrick, Emma and Han, Xu and Liu, Weimin and Corcoran, Eoin and Burtenshaw, Denise and Morrow, David and Helt, Jay-Christian and Cahill, Paul A. and Redmond, Eileen M. (2017) 'Alcohol Reduces Arterial Remodeling by Inhibiting Sonic Hedgehog-Stimulated Stem Cell Antigen-1 Positive Progenitor Stem Cell Expansion'. 41 (12):2051-2065.
2017 Burtenshaw, D. and Hakimjavadi, R. and Redmond, E.M. and Cahill, P.A. (2017) 'Nox, reactive oxygen species and regulation of vascular cell fate'. 6 (4). Link
2016 Cotter, Eoin J. and Sweeney, Nicholas von Offenberg and Coen, Paul M. and Birney, Yvonne A. and Glucksman, Marc J. and Cahill, Paul A. and Cummins, Philip M. (2016) 'Regulation of Endopeptidases EC3.4.24.15 and EC3.4.24.16 in Vascular Endothelial Cells by Cyclic Strain: Role of Gi Protein Signaling'. 5 (1).
2016 Liu, Y. and Zahedmanesh, H. and Lally, C. and Cahill, P. A. and McGuinness, G. B. (2016) 'Compliance properties of a composite electrospun fibre - hydrogel blood vessel scaffold'. 178 :296-299.
2016 Cahill, P.A. and Redmond, E.M. (2016) 'Vascular endothelium - Gatekeeper of vessel health'. 248 :97-109. Link
2016 Liu Y.;Zahedmanesh H.;Lally C.;Cahill P.;McGuinness G. (2016) 'Compliance properties of a composite electrospun fibre - Hydrogel blood vessel scaffold'. Materials Letters, 178 :296-299.
2016 Paşcu, E.I. and Cahill, P.A. and Stokes, J. and McGuinness, G.B. (2016) 'Towards functional 3D-stacked electrospun composite scaffolds of PHBV, silk fibroin and nanohydroxyapatite: Mechanical properties and surface osteogenic differentiation'. 30 (9):1334-1339. Link
2015 Hatch, E. and Morrow, D. and Liu, W. and Cahill, P.A. and Redmond, E.M. (2015) 'Ethanol Inhibits γ-Secretase Proteolytic Activity in Vascular Smooth Muscle Cells'. 39 (11):2115-2122. Link
2015 Mooney, Ciaran J. and Hakimjavadi, Roya and Fitzpatrick, Emma and Kennedy, Eimear and Walls, Dermot and Morrow, David and Redmond, Eileen M. and Cahill, Paul A. (2015) 'Hedgehog and Resident Vascular Stem Cell Fate'. .
2015 Doyle, A.J. and Redmond, E.M. and Gillespie, D.L. and Knight, P.A. and Cullen, J.P. and Cahill, P.A. and Morrow, D.J. (2015) 'Differential expression of Hedgehog/Notch and transforming growth factor-β in human abdominal aortic aneurysms'. 62 (2):464-470. Link
2015 Pa\cscu, E.I. and Cahill, P.A. and McGuinness, G.B. and Stokes, J. (2015) 'Electrospun composites of PHBV, silk fibroin and nano-hydroxyapatite: mechanical properties and biological characterisation'. .
2015 Mooney, C.J. and Hakimjavadi, R. and Fitzpatrick, E. and Kennedy, E. and Walls, D. and Morrow, D. and Redmond, E.M. and Cahill, P.A. (2015) 'Hedgehog and Resident Vascular Stem Cell Fate'. 2015 . Link
2015 Oliveira, R.N. and McGuinness, G.B. and Rouze, R. and Quilty, B. and Cahill, P. and Soares, G.D.A. and Thiré, R.M.S.M. (2015) 'PVA hydrogels loaded with a Brazilian propolis for burn wound healing applications'. 132 (25). Link
2014 Campion, Eva M. and Hakimjavadi, Roya and Loughran, Sinead T. and Phelan, Susan and Smith, Sinead M. and D'Souza, Brendan N. and Tierney, Rosemary J. and Bell, Andrew I. and Cahill, Paul A. and Walls, Dermot (2014) 'Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor beta 1-Induced B-Cell Apoptosis'. 88 (9):5001-5013.
2014 Kennedy, E. and Hakimjavadi, R. and Greene, C. and Mooney, C.J. and Fitzpatrick, E. and Collins, L.E. and Loscher, C.E. and Guha, S. and Morrow, D. and Redmond, E.M. and Cahill, P.A. (2014) 'Embryonic rat vascular smooth muscle cells revisited - A model for neonatal, neointimal SMC or differentiated vascular stem cells?'. 6 (1). Link
2014 Campion, E.M. and Hakimjavadi, R. and Loughran, S.T. and Phelan, S. and Smith, S.M. and D'Souza, B.N. and Tierney, R.J. and Bell, A.I. and Cahill, P.A. and Walls, D. (2014) 'Repression of the proapoptotic cellular BIK/NBK gene by Epstein-Barr virus antagonizes transforming growth factor β1-induced bcell apoptosis'. 88 (9):5001-5013. Link
2014 Morrow, David and Hatch, Ekaterina and Hamm, Katie and Cahill, Paul A. and Redmond, Eileen M. (2014) 'Flk-1/KDR Mediates Ethanol-Stimulated Endothelial Cell Notch Signaling and Angiogenic Activity'. 51 (4):315-324.
2014 Morrow, D. and Hatch, E. and Hamm, K. and Cahill, P.A. and Redmond, E.M. (2014) 'Flk-1/KDR mediates ethanol-stimulated endothelial cell notch signaling and angiogenic activity'. 51 (4):315-324. Link
2014 Gao, W. and Ferguson, G. and Connell, P. and Walshe, T. and O'Brien, C. and Redmond, E.M. and Cahill, P.A. (2014) 'Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression'. 11 (4):270-280. Link
2013 Redmond, E.M. and Hamm, K. and Cullen, J.P. and Hatch, E. and Cahill, P.A. and Morrow, D. (2013) 'Inhibition of patched-1 prevents injury-induced neointimal hyperplasia'. 33 (8):1960-1964. Link
2012 Vrana, N.E. and Matsumura, K. and Hyon, S.-H. and Geever, L.M. and Kennedy, J.E. and Lyons, J.G. and Higginbotham, C.L. and Cahill, P.A. and McGuinness, G.B. (2012) 'Cell encapsulation and cryostorage in PVA-gelatin cryogels: Incorporation of carboxylated ε-poly-L-lysine as cryoprotectant'. 6 (4):280-290. Link
2012 Redmond, E.M. and Cahill, P.A. (2012) 'The NOX-ROS connection: Targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells'. 93 (3):386-387. Link
2011 Guha, S. and Cullen, J.P. and Morrow, D. and Colombo, A. and Lally, C. and Walls, D. and Redmond, E.M. and Cahill, P.A. (2011) 'Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: Role in cell proliferation and survival'. 106 (5):773-785. Link
2011 Walshe, T.E. and Connell, P. and Cryan, L. and Ferguson, G. and Obrien, C. and Cahill, P.A. (2011) 'The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation'. 89 (3):661-670. Link
2011 Redmond, E.M. and Guha, S. and Walls, D. and Cahill, P.A. (2011) 'Investigational Notch and Hedgehog inhibitors therapies for cardiovascular disease'. 20 (12):1649-1664. Link
2011 Walshe, T.E. and Connell, P. and Cryan, L. and Ferguson, G. and Gardiner, T. and Morrow, D. and Redmond, E.M. and O'Brien, C. and Cahill, P.A. (2011) 'Microvascular retinal endothelial and pericyte cell apoptosis in vitro: Role of hedgehog and notch signaling'. 52 (7):4472-4483. Link
2010 Liu, Y. and Bolger, B. and Cahill, P.A. and McGuinness, G.B. (2010) 'Assembly of aligned polyvinyl alcohol-styrylpyridinium pendent group nanofibres for vascular tissue engineering applications'. 223 (3):99-111. Link
2010 Liu, Y. and Geever, L.M. and Kennedy, J.E. and Higginbotham, C.L. and Cahill, P.A. and McGuinness, G.B. (2010) 'Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels'. 3 (2):203-209. Link
2010 Vrana, N.E. and Cahill, P.A. and McGuinness, G.B. (2010) 'Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: Effect of disturbed shear stress conditions'. 94 (4):1080-1090. Link
2010 Morrow, D. and Cullen, J.P. and Liu, W. and Cahill, P.A. and Redmond, E.M. (2010) 'Alcohol inhibits smooth muscle cell proliferation via regulation of the notch signaling pathway'. 30 (12):2597-2603. Link
2009 Tate, Matthew and Jagger, Christopher and Cahill, Paul A. and Hughes, Christopher and Birrell, Louise and Knight, Andrew W. and Billinton, Nicholas and Walmsley, Richard M. (2009) 'Genotoxicity of metabolites: An evaluation of the GreenScreen HC GADD45a-GFP assay in detecting S9-generated metabolites using flow cytometry'. 24 (1):105-106.
2009 Liu, Y. and Vrana, N.E. and Cahill, P.A. and McGuinness, G.B. (2009) 'Physically crosslinked composite hydrogels of PVA with natural macromolecules: Structure, mechanical properties, and endothelial cell compatibility'. 90 B (2):492-502. Link
2009 Jagger, Christopher and Tate, Matthew and Cahill, Paul A. and Hughes, Chris and Knight, Andrew W. and Billinton, Nicholas and Walmsley, Richard M. (2009) 'Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay'. 24 (1):35-50.
2009 Morrow, D. and Cullen, J.P. and Liu, W. and Guha, S. and Sweeney, C. and Birney, Y.A. and Collins, N. and Walls, D. and Redmond, E.M. and Cahill, P.A. (2009) 'Sonic hedgehog induces notch target gene expression in vascular smooth muscle cells via VEGF-A'. 29 (7):1112-1118. Link
2008 Morrow, D. and Cullen, J.P. and Cahill, P.A. and Redmond, E.M. (2008) 'Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway'. 79 (2):313-321. Link
2008 Walmsley, R. M. and Tate, M. and Jagger, C. and Rabinowitz, A. and Hughes, C. and Cahill, P. A. and Knight, A. and Billinton, N. (2008) 'Identification of promutagens using `S9', hepatocytes and HepaRG cells, with the GADD45aGFP genotoxicity assay'. 49 (7).
2008 Moran, D.M. and Mattocks, M.A. and Cahill, P.A. and Koniaris, L.G. and McKillop, I.H. (2008) 'Interleukin-6 Mediates G0/G1 Growth Arrest in Hepatocellular Carcinoma Through a STAT 3-Dependent Pathway'. 147 (1):23-33. Link
2008 Colgan, O.C. and Collins, N.T. and Ferguson, G. and Murphy, R.P. and Birney, Y.A. and Cahill, P.A. and Cummins, P.M. (2008) 'Influence of basolateral condition on the regulation of brain microvascular endothelial tight junction properties and barrier function'. 1193 :84-92. Link
2008 Morrow, D. and Guha, S. and Sweeney, C. and Birney, Y. and Walshe, T. and O'Brien, C. and Walls, D. and Redmond, E.M. and Cahill, P.A. (2008) 'Notch and vascular smooth muscle cell phenotype'. 103 (12):1370-1382. Link
2008 Vrana, N.E. and Yurong, L. and Cahill, P.A. and McGuinness, G.B. (2008) 'Characterization of PVA (polyvinyl alcohol)/chitosan hydrogels as vascular tissue engineering scaffolds (Macromolecular Symposia (2008) 269 (106-110))'. 269 (1). Link
2007 Gao, W. and Ferguson, G. and Connell, P. and Walshe, T. and Murphy, R. and Birney, Y.A. and O'Brien, C. and Cahill, P.A. (2007) 'High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1α-dependent pathway'. 42 (3):609-619. Link
2007 Cullen, J.P. and Morrow, D. and Jin, Y. and Curley, B. and Robinson, A. and Sitzmann, J.V. and Cahill, P.A. and Redmond, E.M. (2007) 'Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion'. 44 (1):75-84. Link
2007 Morrow, D. and Cullen, J.P. and Cahill, P.A. and Redmond, E.M. (2007) 'Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: Role in angiogenic activity'. 27 (6):1289-1296. Link
2007 Knight, Andrew W. and Billinton, N. and Cahill, P. A. and Scott, A. and Harvey, J. S. and Roberts, K. J. and Tweats, D. J. and Keenan, P. O. and Walmsley, R. M. (2007) 'An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC) - including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds'. 22 (6):409-416.
2007 Morrow, D. and Sweeney, C. and Guha, S. and Walshe, T. and O'Brien, C. and Walls, D. and Redmond, E.M. and Cahill, P.A. (2007) 'Notch signaling and vascular cell fate - How vascular cells respond to stress'. 119 (SUPPL. 1):7-10. Link
2007 Keenan, Patrick O. and Knight, Andrew W. and Billinton, Nicholas and Cahill, Paul A. and Dalrymple, Ian M. and Hawkyard, Christopher J. and Stratton-Campbell, Duncan and Walmsley, Richard M. (2007) 'Clear and present danger? The use of a yeast biosensor to monitor changes in the toxicity of industrial effluents subjected to oxidative colour removal treatments'. 9 (12):1394-1401.
2007 Walmsley, R. M. and Billinton, N. and Jagger, C. P. and Hastwell, P. W. and Knight, A. W. and Birrell, L. and Cahill, P. A. (2007) 'Genotoxicity assessment using a GADD45a-GFP reporter assay in a p53 competent human cell host: Metabolic activation, flow cytometry and data update'. 48 (7).
2006 Pegman, P.M. and Smith, S.M. and D'Souza, B.N. and Loughran, S.T. and Maier, S. and Kempkes, B. and Cahill, P.A. and Simmons, M.J. and Gélinas, C. and Walls, D. (2006) 'Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJκ-dependent pathway'. 80 (16):8133-8144. Link
2006 Moran, D.M. and Koniaris, L.G. and Jablonski, E.M. and Cahill, P.A. and Halberstad, C.R. and McKillop, I.H. (2006) 'Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression'. 15 (8-9):785-798. Link
2005 Cahill, PA (2005) 'The `shattering of the self': Violence, subjectivity, and early modern texts'. 103 (1):109-113.
2005 Walshe T.;Ferguson G.;Connell P.;O'Brien C.;Cahill P. (2005) 'Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature'. Investigative Ophthalmology & Visual Science, 46 (1):375-382.
2005 Cullen, J.P. and Sayeed, S. and Kim, Y. and Theodorakis, N.G. and Sitzmann, J.V. and Cahill, P.A. and Redmond, E.M. (2005) 'Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type I, matrix metalloproteinase-2 and -9'. 94 (3):639-645. Link
2005 Walshe, T.E. and Ferguson, G. and Connell, P. and O'Brien, C. and Cahill, P.A. (2005) 'Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature'. 46 (1):375-382. Link
2005 Moran, D.M. and Mayes, N. and Koniaris, L.G. and Cahill, P.A. and McKillop, I.H. (2005) 'Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma'. 25 (2):445-457. Link
2005 Van Gompel, J and Woestenborghs, F and Beerens, D and Mackie, C and Cahill, PA and Knight, AW and Billinton, N and Tweats, DJ and Walmsley, RM (2005) 'An assessment of the utility of the yeast GreenScreen assay in pharmaceutical screening'. 20 (6):449-454.
2004 Sweeney, C. and Morrow, D. and Birney, Y.A. and Coyle, S. and Hennessy, C. and Scheller, A. and Cummins, P.M. and Walls, D. and Redmond, E.M. and Cahill, P.A. (2004) 'Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway'. 18 (12):1421-1423. Link
2004 Birney, Y.A. and Sweeney, C.H. and Cappadona, C.R. and Sitzmann, J.V. and Cummins, P.M. and Redmond, E.M. and Cahill, P.A. (2004) 'Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner'. 41 (4):364-374. Link
2004 Coen, P.M. and Cummins, P.M. and Birney, Y.A. and Devery, R. and Cahill, P.A. (2004) 'Modulation of nitric oxide and 6-keto-prostaglandin F1α production in bovine aortic endothelial cells by conjugated linoleic acid'. 11 (3-4):211-220. Link
2004 Cullen, J.P. and Nicholl, S.M. and Sayeed, S. and Sitzmann, J.V. and Okada, S.S. and Cahill, P.A. and Redmond, E.M. (2004) 'Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration'. 114 (1):57-65. Link
2004 Cotter, E.J. and Von Offenberg Sweeney, N. and Coen, P.M. and Birney, Y.A. and Glucksman, M.J. and Cahill, P.A. and Cummins, P.M. (2004) 'Regulation of Endopeptidases EC3.4.24.15 and EC3.4.24.16 in Vascular Endothelial Cells by Cyclic Strain: Role of Gi Protein Signaling'. 24 (3):457-463. Link
2004 Cummins, P.M. and Cotter, E.J. and Cahill, P.A. (2004) 'Hemodynamic regulation of metallopeptidases within the vasculature'. 11 (5):433-442. Link
2003 Kim, S.I. and Grum-Tokars, V. and Swanson, T.A. and Cotter, E.J. and Cahill, P.A. and Roberts, J.L. and Cummins, P.M. and Glucksman, M.J. (2003) 'Novel Roles of Neuropeptide Processing Enzymes: EC3.4.24.15 in the Neurome'. 74 (3):456-467. Link
2003 Theodorakis, N.G. and Wang, Y.-N. and Skill, N.J. and Metz, M.A. and Cahill, P.A. and Redmond, E.M. and Sitzmann, J.V. (2003) 'The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: Studies in gene-knockout mice'. 124 (5):1500-1508. Link
2002 Price, J.A. and Kovach, S.J. and Johnson, T. and Koniaris, L.G. and Cahill, P.A. and Sitzmann, J.V. and McKillop, I.H. (2002) 'Insulin-like growth factor I is a comitogen for hepatocyte growth factor in a rat model of hepatocellular carcinoma'. 36 (5 5 II):1089-1097. Link
2002 Cullen, J.P. and Sayeed, S. and Sawai, R.S. and Theodorakis, N.G. and Cahill, P.A. and Sitzmann, J.V. and Redmond, E.M. (2002) 'Pulsatile flow-induced angiogenesis: Role of Gi subunits'. 22 (10):1610-1616. Link
2001 Redmond, E.M. and Cullen, J.P. and Cahill, P.A. and Sitzmann, J.V. and Stefansson, S. and Lawrence, D.A. and Okada, S.S. (2001) 'Endothelial cells inhibit flow-induced smooth muscle cell migration: Role of plasminogen activator inhibitor-1'. 103 (4):597-603. Link
2000 Redmond, E.M. and Sitzmann, J.V. and Cahill, P.A. (2000) 'Potential mechanisms for cardiovascular protective effect of ethanol'. 21 (5):385-390. Link
1999 McKillop, I.H. and Max Schmidt, C. and Cahill, P.A. and Sitzmann, J.V. (1999) 'Altered Gq/G11 guanine nucleotide regulatory protein expression in a rat model of hepatocellular carcinoma: Role in mitogenesis'. 29 (2):371-378. Link
1999 Hendrickson, R.J. and Cappadona, C. and Yankah, E.N. and Sitzmann, J.V. and Cahill, P.A. and Redmond, E.M. (1999) 'Sustained pulsatile flow regulates endothelial nitric oxide synthase and cyclooxygenase expression in co-cultured vascular endothelial and smooth muscle cells'. 31 (3):619-629. Link
1999 Cappadona, C. and Redmond, E.M. and Theodorakis, N.G. and McKillop, I.H. and Hendrickson, R. and Chhabra, A. and Sitzmann, J.V. and Cahill, P.A. (1999) 'Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro'. 250 (1):174-186. Link
1999 McKillop, I.H. and Schmidt, C.M. and Cahill, P.A. and Sitzmann, J.V. (1999) 'Inhibitory guanine nucleotide regulatory protein activation of mitogen-activated protein kinase in experimental hepatocellular carcinoma in vitro'. 11 (7):761-768. Link
1999 Schmidt, C.M. and McKillop, I.H. and Cahill, P.A. and Sitzmann, J.V. (1999) 'The role of cAMP-MAPK signalling in the regulation of human hepatocellular carcinoma growth in vitro'. 11 (12):1393-1399. Link
1999 Hendrickson, R.J. and Cahill, P.A. and Sitzmann, J.V. and Redmond, E.M. (1999) 'Ethanol enhances basal and flow-stimulated nitric oxide synthase activity in vitro by activating an inhibitory guanine nucleotide binding protein'. 289 (3):1293-1300. Link
1999 McKillop, I.H. and Vyas, N. and Max Schmidt, C. and Cahill, P.A. and Sitzmann, J.V. (1999) 'Enhanced Gi-protein-mediated mitogenesis following chronic ethanol exposure in a rat model of experimental hepatocellular carcinoma'. 29 (2):412-420. Link
1999 Kouretas, P.C. and Kim, Y.D. and Cahill, P.A. and Myers, A.K. and To, L.N. and Wang, Y.-N. and Sitzmann, J.V. and Hannan, R.L. (1999) 'Nonanticoagulant heparin prevents coronary endothelial dysfunction after brief ischemia-reperfusion injury in the dog'. 99 (8):1062-1068. Link
1999 Cahill, P.A. (1999) 'Vasoconstrictor responsiveness of portal hypertensive vessels'. 96 (1):3-4. Link
1999 Redmond, E.M. and Cahill, P.A. and Hirsch, M. and Wang, Y.-N. and Sitzmann, J.V. and Okada, S.S. (1999) 'Effect of pulse pressure on vascular smooth muscle cell migration: The role of urokinase and matrix metalloproteinase'. 81 (2):293-300. Link
1999 Hendrickson, R.J. and Okada, S.S. and Cahill, P.A. and Yankah, E. and Sitzmann, J.V. and Redmond, E.M. (1999) 'Ethanol inhibits basal and flow-induced vascular smooth muscle cell migration in vitro'. 84 (1):64-70. Link
1998 Hubbard, SF and Petschek, RG and Singer, KD and D'Sidocky, N and Hudson, C and Chien, LC and Henderson, CC and Cahill, PA (1998) 'Measurements of Kleinman-disallowed hyperpolarizability in conjugated chiral molecules'. 15 (1):289-301.
1998 McKillop, I.H. and Wu, Y. and Cahill, P.A. and Sitzmann, J.V. (1998) 'Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi-proteins) in experimental hepatocellular carcinoma'. 175 (3):295-304. Link
1998 Kouretas, P.C. and Hannan, R.L. and Kapur, N.K. and Hendrickson, R. and Redmond, E.M. and Myers, A.K. and Kim, Y.D. and Cahill, P.A. and Sitzmann, J.V. (1998) 'Non-anticoagulant heparin increases endothelial nitric oxide synthase activity: Role of inhibitory guanine nucleotide proteins'. 30 (12):2669-2682. Link
1998 Redmond, E.M. and Cahill, P.A. and Sitzmann, J.V. (1998) 'Flow-mediated regulation of G-protein expression in cocultured vascular smooth muscle and endothelial cells'. 18 (1):75-83. Link
1998 Kouretas, P.C. and Myers, A.K. and Kim, Y.D. and Cahill, P.A. and Myers, J.L. and Wang Y.-, N. and Sitzmann, J.V. and Wallace, R.B. and Hannan, R.L. and Del Nido, P.J. and Sellke, F.W. and Mayer J.E., Jr. and Buxton, B. and Verrier, E.D. and Hirsch, G.M. (1998) 'Heparin and nonanticoagulant heparin preserve regional myocardial contractility after ischemia-reperfusion injury: Role of nitric oxide'. 115 (2):440-449. Link
1998 Kouretas, P.C. and Kim, Y.D. and Cahill, P.A. and Myers, A.K. and To, L.N. and Wang, Y.-N. and Wallace, R.B. and Kron, I.L. and Hannan, R.L. (1998) 'Heparin preserves nitric oxide activity in coronary endothelium during ischemia-reperfusion injury'. 66 (4):1210-1215. Link
1998 Cahill, P.A. and Hou, M.-C. and Hendrickson, R. and Wang, Y.I.-N. and Zhang, S. and Redmond, E.M. and Sitzmann, J.V. (1998) 'Increased expression of endothelin receptors in the vasculature of portal hypertensive rats: Role in splanchnic hemodynamics'. 28 (2):396-403. Link
1997 Kapur, N.K. and Kouretas, P.C. and Myers, A.K. and Cahill, P.A. and Kim, Y.D. and Wang, Y.N. and Redmond, E.M. and Sitzmann, J.V. and Hannan, R.L. (1997) 'Endothelial-dependent vasodilation of thoracic aorta by heparin and non-anticoagulant heparin'. 11 (3). Link
1997 Rohlfing, CM and Cahill, PA (1997) 'A quantum chemical study of the isomers of bis(methano)fullerene, C-60(CH2)(2)'. 91 (3):561-565.
1997 Lee, JM and Crowley, B and Cahill, PA and OBriain, DS and Keane, C and Gill, DG and OMorain, CA (1997) 'Escherichia coli O157:H7 - Two case reports'. 166 (1):20-22.
1997 Gerbes, A.L. and Cahill, P.A. (1997) 'Quantitative discrimination of ANF receptor subtypes in portal hypertension [5]'. 26 (2):450-451. Link
1997 Redmond, E.M. and Cahill, P.A. and Sitzmann, J.V. (1997) 'Flow-mediated regulation of endothelin receptors in cocultured vascular smooth muscle cells: An endothelium-dependent effect'. 34 (6):425-435. Link
1997 Mckillop, I.H. and Johnson, T. and Sabharwal, P. and Schmidt, C.M. and Cahill, P.A. and Sitzmann, J.V. (1997) 'Hepatic insulin-like growth factor-I (IGF-I) receptor and mRNA expression in experimental hepatocellular carcinoma (HCC)'. 11 (3). Link
1997 Hou, M.-C. and Cahill, P.A. and Zhang, S. and Redmond, E.M. and Sitzmann, J.V. (1997) 'Enhanced G-protein-induced relaxation in portal hypertensive rats: Role of nitric oxide'. 26 (1):27-33. Link
1997 Schmidt, C.M. and McKillop, I.H. and Cahill, P.A. and Sitzmann, J.V. (1997) 'Increased MAPK expression and activity in primary human hepatocellular carcinoma'. 236 (1):54-58. Link
1996 Cahill, P.A. and Redmond, E.M. and Wu, Y. and Sitzmann, J.V. (1996) 'Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits'. 24 (2):185-193. Link
1996 Redmond, E.M. and Cahill, P.A. and Stemann, J.V. (1996) 'Shear stress-mediated regulation of g-protein expression in vascular smooth muscle cells co-cultured with endothelial cells'. 10 (3). Link
1996 McKillod, H. and Scbmidt, C.M. and Cahill, P.A. and Sifmiym, J.V. (1996) 'Ethanol upregulates Giα protein expression in an experimental hepatoma cell line; Possible role in the progression of HCC growth'. 10 (6). Link
1996 Cahill, PA (1996) 'Ab initio computational study of selected C60H6 isomers'. 254 (3-4):257-262.
1996 Schmidt, C.M. and Cahill, P.A. and McKillop, J.H. and Redmond, E.M. and Sitzmann, I.V. (1996) 'Increased expression of guandve niicleotide regulatory proteins gqtt/gm in hepatocelllilar carcinoma (HCC)'. 10 (3). Link
1996 Yamamoto, S. and Burman, H. and O'Donnell, C.P. and Cahill, P.A. and Robotham, J.L. (1996) 'Endothelin causes portal and pulmonary hypertension in porcine endotoxemia'. 10 (3). Link
1996 Cahill, P.A. and Redmond, E.M. and Hodges, R. and Zhang, S. and Sitzmann, J.V. (1996) 'Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats'. 25 (3):370-378. Link
1996 Redmond, E.M. and Cahill, P.A. and Sitzmann, J.V. (1996) 'Shear stress-mediated regulation of G-protein expression in co-cultured vascular smooth muscle cells and endothelial cells'. 10 (6). Link
1996 De Maio, A. and Ginoalewski, C. and Sitzmann, J.V. and Cahill, P.A. (1996) 'Expression of inducible nitric oxide synthase in rat lung following regional hepatic ischemia/reperfusion injury'. 10 (3). Link
1996 Redmond, E.M. and Cahill, P.A. and Hodges, R. and Zhang, S. and Sitzmann, J.V. (1996) 'Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells'. 166 (3):469-479. Link
1996 Cahill, P.A. and Redmond, E.M. and Sitzmann, J.V. (1996) 'Regulation of Gia-Protein expression by nitric oxide in bovine aortic endothelial cells'. 10 (3). Link
1996 McKillop, I. and Cahill, P.A. and Sitzmann, J.V. (1996) 'Activation of Gia proteins stimulates c-myc expression and cellular proliferation in hepatocellular carcinoma'. 10 (3). Link
1996 Sabharwal, P. and McKillop, I. and Demaio, A. and Cahill, P.A. and Sitzmann, J.V. (1996) 'Heat-shock protein expression (HSP-72) in rat hepatocellular carcinoma following cryoablation'. 10 (3). Link
1995 Cahill, P.A. and Redmond, E.M. and Foster, C. and Sitzmann, J.V. (1995) 'Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells'. 288 (2):219-229. Link
1995 KOWALCZYK, TC and KOSC, TZ and SINGER, KD and BEUHLER, AJ and WARGOWSKI, DA and CAHILL, PA and SEAGER, CH and MEINHARDT, MB and ERMER, S (1995) 'CROSS-LINKED POLYIMIDE ELECTROOPTIC MATERIALS'. 78 (10):5876-5883.
1995 KOWALCZYK, TC and SINGER, KD and CAHILL, PA (1995) 'ANOMALOUS-DISPERSION PHASE-MATCHED 2ND-HARMONIC GENERATION IN A POLYMER WAVE-GUIDE'. 20 (22):2273-2275.
1995 KEPLER, RG and BEESON, PM and JACOBS, SJ and ANDERSON, RA and SINCLAIR, MB and VALENCIA, VS and CAHILL, PA (1995) 'ELECTRON AND HOLE MOBILITY IN TRIS(8-HYDROXYQUINALINOLATO-N1,O8) ALUMINUM'. 66 (26):3618-3620.
1995 Maher, M.M. and Gontarek, J.D. and Jimenez, R.E. and Cahill, P.A. and Yeo, C.J. (1995) 'Endogenous nitric oxide promotes ileal absorption'. 58 (6):687-692. Link
1995 Cahill, P.A. and Sitzmann, J.V. (1995) 'Nitric oxide and portal hypertension'. 23 (3):355-356. Link
1995 Redmond, E.M. and Cahill, P.A. and Sitzmann, J.V. (1995) 'Perfused transcapillary smooth muscle and endothelial cell co-culture—a novel in vitro model'. 31 (8):601-609. Link
1995 Sitzmann, J.V. and Wu, Y. and Aguilera, G. and Cahill, P.A. and Burns, R.C. (1995) 'Loss of angiotensin-II receptors in portal hypertensive rabbits'. 22 (2):559-564. Link
1994 HENDERSON, CC and ROHLFING, CM and ASSINK, RA and CAHILL, PA (1994) 'C60H4 - KINETICS AND THERMODYNAMICS OF MULTIPLE ADDITION TO C-60'. 33 (7):786-788.
1994 KOWALCZYK, TC and KOSC, T and SINGER, KD and CAHILL, PA and SEAGER, CH and MEINHARDT, MB and BEUHLER, AJ and WARGOWSKI, DA (1994) 'LOSS MECHANISMS IN POLYIMIDE WAVE-GUIDES'. 76 (4):2505-2508.
1994 IRWIN, AD and ASSINK, RA and HENDERSON, CC and CAHILL, PA (1994) 'STUDY OF THE REORIENTATIONAL MOTION OF C60H2 IN TOLUENE-D(8) BY PROTON NMR'. 98 (46):11832-11834.
1994 HENDERSON, CC and ROHLFING, CM and GILLEN, KT and CAHILL, PA (1994) 'SYNTHESIS, ISOLATION, AND EQUILIBRATION OF 1,9-C70H2 AND 7,8-C70H2'. 264 (5157):397-399.
1993 Cahill, P.A. and Hassid, A. (1993) 'Differential antimitogenic effectiveness of atrial natriuretic peptides in primary versus subcultured rat aortic smooth muscle cells: Relationship to expression of ANF‐C receptors'. 154 (1):28-38. Link
1990 Redmond, E.M. and Cahill, P.A. and Keenan, A.K. (1990) 'Atrial natriuretic factor recognizes two receptor subtypes in endothelial cells cultured from bovine pulmonary artery'. 269 (1):157-162. Link
1990 McCabe, J.P. and Waldron, R.P. and Kerin, M.J. and Courtney, D.F. and Given, H.F. and McAnena, O.J. and Grimes, H. and Tymkewycz, P.M. and Gascoine, P.S. and Gaffney, P.J. and Felle, P. and Gaine, S. and Cox, J. and England, R. and Walsh, J. and Coakley, D. and Feely, J. and O'Brien, E. and O'Malley, K. and Daly, L. and Sheppard, B.L. and Carroll, E. and Hennelly, B. and Bonnar, J. and Fahy, M.M. and Carragher, V. and Kane, M.T. and McGuinness, S. and Pratt, I. and Ryan, M.P. and Cahill, P.A. and Daly, S. and Keenan, A.K. and Barrett, R.P. and Rowan, M.J. and Smyth, M. and O'Cuinn, G. and Sharma, S.C. and Sheppard, B.L. and Bonnar, J. and Feely, S. and Kennedy, M. and O'Regan, R.G. and Hughes, G. and Allen, J.M. and McHale, N.G. and Thombury, K.D. and Croal, S. and Anderson, J.M. and Allen (1990) 'Royal academy of medicine in ireland section of biological sciences - Proceedings of the section of biological sciences section, summer meeting, ucg, 23rd & 24th june, 1989'. 159 (1):23-37. Link
1990 Cahill, P.A. and Redmond, E.M. and Keenan, A.K. (1990) 'Vascular atrial natriuretic factor receptor subtypes are not independently regulated by atrial peptides'. 265 (35):21896-21906. Link
1989 Andrews, J.F. and Cabot, D. and Jakobson, M.E. and McBennett, S. and Fallon, C. and Orr, D. and Collins, L. and Fitzpatrick, F. and O'Brien, M. and Vincent Young, W. and Brown, S. and Lyons, F. and Donoghue, J. and Kelly, L. and Boyle, J. and Canavan, R. and Donne, B. and Kelly, M. and Barry, J.J. and Leonard, C. and McLoughlin, J.V. and Tait, S. and Treacy, M. and Larkin, S. and Schuster, W.A. and Martin, F. and Lynch, C. and Cahill, P.A. and Redmond, E. and Keenan, A.K. and Barron, T. and McGuiness, S. and Pratt, I. and Ryan, M.P. and O'Donovan, D.J. and Lam, P.Y. and Young, T. and Benson, P. and Fitzpatrick, G. and Moriarty, D.C. and Ghaly, R.G. and Dundee, J.W. and Fitzpatrick, K.T.J. and Fee, E. and McKay, A.C. and Clarke, R.S.J. and McKinney, M.S. and Fee, J.P.H. and Dwyer, R. and cl (1989) 'Royal Academy Of Medicine In Ireland Section Of Biological Sciences - Winter Meeting 1989, held on 6th January, 1989'. 158 (5):121-131. Link
2016 Paşcu E.;Cahill P.;Stokes J.;McGuinness G. (2016) 'Towards functional 3D-stacked electrospun composite scaffolds of PHBV, silk fibroin and nanohydroxyapatite: Mechanical properties and surface osteogenic differentiation'. Journal of Biomaterials Applications, 30 (9):1334-1339.
2016 Alshamrani, Maryam and Cahill, Paul A. (2016) 'Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease'. 111 (1).
2016 Pascu, Elena I. and Cahill, Paul A. and Stokes, Joseph and McGuinness, Garrett B. (2016) 'Towards functional 3D-stacked electrospun composite scaffolds of PHBV, silk fibroin and nanohydroxyapatite: Mechanical properties and surface osteogenic differentiation'. 30 (9):1334-1349.
2016 Cahill, Paul A. and Redmond, Eileen M. (2016) 'Vascular endothelium - Gatekeeper of vessel health'. 248 :97-109.
2015 Mooney C.;Hakimjavadi R.;Fitzpatrick E.;Kennedy E.;Walls D.;Morrow D.;Redmond E.;Cahill P. (2015) 'Hedgehog and Resident Vascular Stem Cell Fate'. Stem Cells International, 2015 .
2015 Oliveira, R.N., McGuinness, G.B., Rouzée, R., Quilty, B., Cahill, P.A., Soares, G.D.A., Thiré, R.M.S.M. (2015) 'PVA hydrogels loaded with a Brazilian propolis for burn wound healing applications'. Journal of Applied Polymer Science, 132 (25).
2015 Doyle, Adam J. and Redmond, Eileen M. and Gillespie, David L. and Knight, Peter A. and Cullen, John P. and Cahill, Paul A. and Morrow, David J. (2015) 'Differential expression of Hedgehog/Notch and transforming growth factor-beta in human abdominal aortic aneurysms'. 62 (2):464-470.
2015 Hatch, Ekaterina and Morrow, David and Liu, Weimin and Cahill, Paul A. and Redmond, Eileen M. (2015) 'Ethanol Inhibits -Secretase Proteolytic Activity in Vascular Smooth Muscle Cells'. 39 (11):2115-2122.
2015 Oliveira, RN;McGuinness, GB;Rouze, R;Quilty, B;Cahill, P;Soares, GDA;Thire, RMSM (2015) 'PVA hydrogels loaded with a Brazilian propolis for burn wound healing applications'. Journal of Applied Polymer Science, 132 .
2014 Redmond E.;Liu W.;Hamm K.;Hatch E.;Cahill P.;Morrow D. (2014) 'Perivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodeling'. PLoS ONE, 9 (1).
2014 Kennedy E.;Hakimjavadi R.;Greene C.;Mooney C.;Fitzpatrick E.;Collins L.;Loscher C.;Guha S.;Morrow D.;Redmond E.;Cahill P. (2014) 'Embryonic rat vascular smooth muscle cells revisited - A model for neonatal, neointimal SMC or differentiated vascular stem cells?'. Vascular Cell, 6 (1).
2014 Morrow D.;Hatch E.;Hamm K.;Cahill P.;Redmond E. (2014) 'Flk-1/KDR mediates ethanol-stimulated endothelial cell notch signaling and angiogenic activity'. Journal of Vascular Research, 51 (4):315-324.
2014 Morrow D, Hatch E, Hamm K, Cahill PA, Redmond EM (2014) 'Flk-1/KDR Mediates Ethanol-Stimulated Endothelial Cell Notch Signaling and Angiogenic Activity'. Journal of Vascular Research, In press .
2014 Kennedy, Eimear and Mooney, Ciaran J. and Hakimjavadi, Roya and Fitzpatrick, Emma and Guha, Shaunta and Collins, Laura E. and Loscher, Christine E. and Morrow, David and Redmond, Eileen M. and Cahill, Paul A. (2014) 'Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells'. 358 (1):203-216.
2014 Gao, Wei and Ferguson, Gail and Connell, Paul and Walshe, Tony and O'Brien, Colm and Redmond, Eileen M. and Cahill, Paul A. (2014) 'Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1 alpha expression'. 11 (4):270-280.
2014 Morrow, D. and Hatch, E. and Hamm, K. and Cahill, P. A. and Redmond, E. M. (2014) 'ETHANOL INHIBITS HEDGEHOG SIGNALING IN CULTURED VASCULAR SMOOTH MUSCLE CELLS AND IN LIGATION-INJURED VESSELS IN VIVO'. 38 (1, SI).
2014 Campion E*.;Hakimjavadi R*.;Loughran S.;Phelan S.;Smith S.;D'Souza B.;Tierney R.;Bell A.;Cahill P.;Walls D. (2014) 'Repression of the proapoptotic cellular BIK/NBK gene by Epstein-Barr virus antagonizes transforming growth factor β1-induced B-cell apoptosis'. Journal of Virology, 88 (9):5001-5013.
2013 Colombo A.;Guha S.;Mackle J.;Cahill P.;Lally C. (2013) 'Cyclic strain amplitude dictates the growth response of vascular smooth muscle cells in vitro: Role in in-stent restenosis and inhibition with a sirolimus drug-eluting stent'. Biomechanics and Modeling in Mechanobiology, 12 (4):671-683.
2013 Redmond E.;Hamm K.;Cullen J.;Hatch E.;Cahill P.;Morrow D. (2013) 'Inhibition of patched-1 prevents injury-induced neointimal hyperplasia'. Arteriosclerosis, Thrombosis, and Vascular Biology, 33 (8):1960-1964.
2013 Redmond, Eileen M. and Hamm, Katie and Cullen, John P. and Hatch, Ekaterina and Cahill, Paul A. and Morrow, David (2013) 'Inhibition of Patched-1 Prevents Injury-Induced Neointimal Hyperplasia'. 33 (8):1960-1964.
2013 Hatch, E. and Morrow, D. and Cahill, P. A. and Redmond, E. M. (2013) 'ALCOHOL REGULATION OF NOTCH SIGNALING IN VASCULAR CELLS'. 37 (2, SI).
2013 Redmond, E.M, Hamm, K., Cullen, J.P. Hatch, E., Cahill, P.A., Morrow, D. (2013) 'Inhibition of patched-1 prevents injury-induced neointimal hyperplasia'. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 33 :1960-1964.
2013 Colombo, Alberto and Guha, Shaunta and Mackle, Joseph N. and Cahill, Paul A. and Lally, Caitriona (2013) 'Cyclic strain amplitude dictates the growth response of vascular smooth muscle cells in vitro: role in in-stent restenosis and inhibition with a sirolimus drug-eluting stent'. 12 (4):671-683.
2012 Vrana N.;Matsumura K.;Hyon S.;Geever L.;Kennedy J.;Lyons J.;Higginbotham C.;Cahill P.;McGuinness G. (2012) 'Cell encapsulation and cryostorage in PVA-gelatin cryogels: Incorporation of carboxylated ε-poly-L-lysine as cryoprotectant'. Journal of tissue engineering and regenerative medicine, 6 (4):280-290.
2012 Campbell E.;Cahill P.;Lally C. (2012) 'Investigation of a small-diameter decellularised artery as a potential scaffold for vascular tissue engineering; biomechanical evaluation and preliminary cell seeding'. Journal of the Mechanical Behavior of Biomedical Materials, 14 :130-142.
2012 Campbell, E. M. and Cahill, P. A. and Lally, C. (2012) 'Investigation of a small-diameter decellularised artery as a potential scaffold for vascular tissue engineering; biomechanical evaluation and preliminary cell seeding'. 14 :130-142.
2012 Slater, Sadie C. and Ramnath, Raina D. and Uttridge, Kate and Saleem, Moin A. and Cahill, Paul A. and Mathieson, Peter W. and Welsh, Gavin I. and Satchell, Simon C. (2012) 'Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes'. 44 (9):1482-1490.
2012 Cahill, Paul A. and Redmond, Eileen M. (2012) 'Alcohol and Cardiovascular Disease-Modulation of Vascular Cell Function'. 4 (4):297-318.
2012 Cahill PA and Redmond EM (2012) 'Alcohol and Cardiovascular Disease- Modulation of Vascular Cell Function. Nutrients'. 4 :297-318.
2012 Redmond, Eileen M. and Cahill, Paul A. (2012) 'The NOXROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells'. 93 (3):386-387.
2012 Redmond EM, Cahill PA (2012) 'The NOX-­‐ROS Connection and Vascular Smooth Muscle Cell Migration - Targeting Nox1 Control of N- Cadherin Shedding In Vascular Cells'. Cardiovascular Research, 93 :386-387.
2012 Campbell EM, Cahill PA and Lally C (2012) 'Investigation of a small-diameter decellularised artery as a potential scaffold for vascular tissue engineering; Biomechanical evaluation and preliminary cell seeding. Journal of Mechanical Behavior of Biomedical Materials'. 14 :130-142.
2012 Redmond EM, Lally C, Cahill PA (2012) 'Hemodynamic control of vascular smooth muscle function'. Muscle, 2 :1231-1242.
2012 Slater SC, Uttridge K, Saleem MA, Cahill PA, Mathieson PW, Welsh GI, Satchell SC. (2012) 'Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes'. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 44 :1432-1490.
2012 Vrana, Nihal E. and Matsumura, Kazuaki and Hyon, Suong-Hyu and Geever, Luke M. and Kennedy, James E. and Lyons, John G. and Higginbotham, Clement L. and Cahill, Paul A. and McGuinness, Garrett B. (2012) 'Cell encapsulation and cryostorage in PVA-gelatin cryogels: incorporation of carboxylated e-poly-L-lysine as cryoprotectant'. 6 (4):280-290.
2011 Guha S.;Cullen J.;Morrow D.;Colombo A.;Lally C.;Walls D.;Redmond E.;Cahill P. (2011) 'Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: Role in cell proliferation and survival'. Basic Research in Cardiology, 106 (5):773-785.
2011 Redmond, Eileen M. and Guha, Shaunta and Walls, Dermot and Cahill, Paul A. (2011) 'Investigational Notch and Hedgehog inhibitors - therapies for cardiovascular disease'. 20 (12):1649-1664.
2011 Guha, Shaunta and Cullen, John P. and Morrow, David and Colombo, Alberto and Lally, Caitriona and Walls, Dermot and Redmond, Eileen M. and Cahill, Paul A. (2011) 'Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survival'. 106 (5):773-785.
2011 Walshe, Tony E. and Connell, Paul and Cryan, Lorna and Ferguson, Gail and Gardiner, Tom and Morrow, David and Redmond, Eileen M. and O'Brien, Colm and Cahill, Paul A. (2011) 'Microvascular Retinal Endothelial and Pericyte Cell Apoptosis In Vitro: Role of Hedgehog and Notch Signaling'. 52 (7):4472-4483.
2011 Walshe, Tony E. and Connell, Paul and Cryan, Lorna and Ferguson, Gail and O'Brien, Colm and Cahill, Paul A. (2011) 'The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation'. 89 (3):661-670.
2011 Redmond EM, Guha S, Walls D, Cahill PA. (2011) 'Investigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease'. Expert Opin Investig Drugs :1649-1664.
2011 Walshe TE, Connell P, Lorna C, Ferguson G, Gardiner T, Morrow D, Redmond EM, O'Brien C, Cahill PA. (2011) 'Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch signaling'. INVESTIGATIVE OPTHAMOLOGY & VISUAL SCIENCE, 52 :4472-44783.
2011 Walshe TE,, Connell P, Cryan L., Ferguson G, O'Brien C and Cahill PA. (2011) 'The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation'. Cardiovascular Research, 89 :661-670.
2011 Guha S., Cullen JP, Morrow D, Colombo A, Lally C, Walls D, Redmond EM , Cahill PA. (2011) 'Glycogen Synthase Kinase 3 beta (GSK-3ß) positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survival. Basic Res Cardiol'. 106 :773-785.
2011 Vrana NE, Matsumura K, Hyon S, Geever LM, Kennedy JE, Lyons JG, Higginbotham CL, Cahill PA, McGuinness GM. (2011) 'Cell Encapsulation and Cryostorage in PVA/Gelatin Cryogels: Incorporation of Carboxylated e-Poly -L-Lysine as Cryoprotectant'. Journal of Tissue Engineering and Regenerative Medicine (in press) .
2011 Bevan HS, Slater SC, Clarke H, Cahill PA, Mathieson PW, Welsh GI, Satchell SC (2011) 'Acute laminar shear stress reversibly increases human glomerular endothelial cell permeability via activation of endothelial nitric oxide synthase'. American Journal of Physiology, 301 :F733-F742.
2010 Colombo A.;Zahedmanesh H.;Toner D.;Cahill P.;Lally C. (2010) 'A method to develop mock arteries suitable for cell seeding and in-vitro cell culture experiments'. Journal of the Mechanical Behavior of Biomedical Materials, 3 (6):470-477.
2010 Vrana N.;Cahill P.;McGuinness G. (2010) 'Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: Effect of disturbed shear stress conditions'. Journal of Biomedical Materials Research - Part A, 94 (4):1080-1090.
2010 Vrana, Nihal Engin and Cahill, Paul A. and McGuinness, Garrett B. (2010) 'Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: Effect of disturbed shear stress conditions'. 94A (4):1080-1090.
2010 Colombo, A. and Zahedmanesh, H. and Toner, D. M. and Cahill, P. A. and Lally, C. (2010) 'A method to develop mock arteries suitable for cell seeding and in-vitro cell culture experiments'. 3 (6):470-477.
2010 Colombo A, Zahedmanesh H, Toner DM, Cahill PA, Lally C. (2010) 'A method to develop mock arteries suitable for cell seeding and in-vitro cell culture experiments. J Mech Behav Biomed Mater'. 3 :470-477.
2010 Morrow D, Cullen JP, Liu W, Cahill PA, Redmond EM. (2010) 'Alcohol Inhibits Smooth Muscle Cell Proliferation via Regulation of The Notch Signaling Pathway. Arterioscler Thromb Vasc Biol. Oct 7. [Epub ahead of print]'. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30 :2597-2603.
2010 Vrana NE, Cahill PA, McGuinness GB. (2010) 'Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: effect of disturbed shear stress conditions.J Biomed Mater Res A'. 94 :1080-1090.
2010 Liu Y, Geever LM, Kennedy JE, Higginbotham CL, Cahill PA, McGuinness GB. (2010) 'Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels. J Mech Behav Biomed Mater'. 3 :203-209.
2010 Liu, Yurong and Geever, Luke M. and Kennedy, James E. and Higginbotham, Clement L. and Cahill, Paul A. and McGuinness, Garrett B. (2010) 'Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels'. 3 (2):203-209.
2009 Liu Y.;Vrana N.;Cahill P.;McGuinness G. (2009) 'Physically crosslinked composite hydrogels of PVA with natural macromolecules: Structure, mechanical properties, and endothelial cell compatibility'. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 90 B (2):492-502.
2009 Vrana, N. E. and O'Grady, A. and Kay, E. and Cahill, P. A. and McGuinness, G. B. (2009) 'Cell encapsulation within PVA-based hydrogels via freeze-thawing: a one-step scaffold formation and cell storage technique'. 3 (7):567-572.
2009 Liu, Y. and Vrana, N. E. and Cahill, P. A. and McGuinness, G. B. (2009) 'Physically Crosslinked Composite Hydrogels of PVA With Natural Macromolecules: Structure, Mechanical Properties, and Endothelial Cell Compatibility'. 90B (2):492-502.
2009 Morrow D, Cullen JP, Liu W, Guha S, Sweeney C, Birney YA, Collins N, Walls D, Redmond EM, Cahill PA. (2009) 'Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A. Arterioscler Thromb Vasc Biol'. 29 :1112-1118.
2009 Liu, Yurong and Bolger, Brian and Cahill, Paul A. and McGuinness, Garrett B. (2009) 'Water resistance of photocrosslinked polyvinyl alcohol based fibers'. 63 (3-4):419-421.
2009 Liu Y, Vrana NE, Cahill PA, McGuinness GB (2009) 'Physically crosslinked composite hydrogels of PVA with natural macromolecules: structure, mechanical properties, and endothelial cell compatibility. J Biomed Mater Res B Appl Biomater'. 90 :492-502.
2009 Morrow, David and Cullen, John P. and Liu, Weimin and Cahill, Paul A. and Redmond, Eileen M. (2009) 'A VEGF-Notch Signaling Pathway Mediates the Effect of Ethanol on Endothelial Angiogenic Activity'. 29 (7).
2008 Colombo A.;Cahill P.;Lally C. (2008) 'An analysis of the strain field in biaxial Flexcell membranes for different waveforms and frequencies'. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 222 (8):1235-1245.
2008 Connell P, Walshe T, Ferguson G, Gao W, O'Brien C, Cahill PA. (2008) 'Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells. Endothelium'. 14 :17-24.
2008 Colombo, A. and Cahill, P. A. and Lally, C. (2008) 'An analysis of the strain field in biaxial Flexcell membranes for different waveforms and frequencies'. 222 (H8):1235-1245.
2008 Morrow, David and Cullen, John P. and Cahill, Paul A. and Redmond, Eileen M. (2008) 'Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway'. 79 (2):313-321.
2008 Mathews, D. T. and Birney, Y. A. and Cahill, P. A. and McGuinness, G. B. (2008) 'Mechanical and morphological characteristics of poly(vinyl alcohol)/chitosan hydrogels'. 109 (2):1129-1137.
2008 Morrow, David and Cullen, John P. and Cahill, Paul A. and Redmond, Eileen M. (2008) 'Stimulation of notch signaling in endothelial cells by ethanol: Role in angiogenesis'. 28 (6).
2008 Moran, Dairmuid M. and Mattocks, M. Adrian and Cahill, Paul A. and Koniaris, Leonidas G. and McKillop, Lain H. (2008) 'Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway'. 147 (1):23-33.
2008 Mathews, D. T. and Birney, Y. A. and Cahill, P. A. and McGuinness, G. B. (2008) 'Vascular cell viability on polyvinyl alcohol hydrogels modified with water-soluble and -insoluble chitosan'. 84B (2):531-540.
2008 Vrana, Nihal Engin and Liu, Yurong and McGuinness, Garret Brian and Cahill, Paul Aidan (2008) 'Characterization of poly(vinyl alcohol)/chitosan hydrogels as vascular tissue engineering scaffolds'. 269 :106-110.
2008 Colgan, Olga C. and Collins, Nota T. and FeTguson, Gail and Murphy, Ronan P. and Bitney, Yvonne A. and Cahill, Paul A. and Cummins, Philip M. (2008) 'Influence of basolateral condition on the regulation of brain microvascular endothelial tight junction properties and barrier function'. 1193 :84-92.
2008 Morrow, David and Guha, Shaunta and Sweeney, Catherine and Birney, Yvonne and Walshe, Tony and O'Brien, Colm and Walls, Dermot and Redmond, Eileen M. and Cahill, Paul A. (2008) 'Notch and Vascular Smooth Muscle Cell Phenotype'. 103 (12):1370-1382.
2008 Colombo A, Cahill PA, Lally C. (2008) 'An analysis of the strain field in biaxial Flexcell membranes for different waveforms and frequencies. Proc Inst Mech Eng H'. 222 :1235-1245.
2008 Tobin NP, Henehan GT, Murphy RP, Atherton JC, Guinan AF, Kerrigan SW, Cox D, Cahill PA, Cummins PM. (2008) 'Helicobacter pylori-induced inhibition of vascular endothelial cell functions: a role for VacA-dependent nitric oxide reduction. Am J Physiol Heart Circ Physiol'. 295 :H1403-H1413.
2008 Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O'Brien C, Walls D, Redmond EM, Cahill PA. (2008) 'Notch and vascular smooth muscle cell phenotype. Circ Res'. 5 :1370-1382.
2008 Mathews DT, Birney YA, Cahill PA, McGuinness GB. (2008) 'Vascular cell viability on polyvinyl alcohol hydrogels modified with water-soluble and -insoluble chitosan. J Biomed Mater Res B Appl Biomater'. 84 :531-540.
2008 Morrow D, Cullen JP, Cahill PA, Redmond EM. (2008) 'Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway. Cardiovasc Res'. 79 :313-321.
2008 Cummins PM, von Offenberg Sweeney N, Killeen MT, Birney YA, Redmond EM, Cahill PA. (2008) 'Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: a force to be reckoned with. Am J Physiol Heart Circ Physiol'. 292 :H28-H42.
2008 Moran DM, Mattocks MA, Cahill PA, Koniaris LG, McKillop IH. (2008) 'Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway. J Surg Res'. 147 :23-33.
2008 Colgan OC, Collins NT, Ferguson G, Murphy RP, Birney YA, Cahill PA, Cummins PM. (2008) 'Influence of basolateral condition on the regulation of brain microvascular endothelial tight junction properties and barrier function. Brain Res'. 1193 :84-92.
2008 Morrow D, Cullen JP, Cahill PA, Redmond EM. (2008) 'Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity. Arterioscler Thromb Vasc Biol'. 27 :1289-1296.
2008 Mathews D.;Birney Y.;Cahill P.;McGuinness G. (2008) 'Vascular cell viability on polyvinyl alcohol hydrogels modified with water-soluble and -insoluble chitosan'. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 84 (2):531-540.
2007 Cullen J.;Morrow D.;Jin Y.;von Offenberg Sweeney N.;Sitzmann J.;Cahill P.;Redmond E. (2007) 'Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes'. Atherosclerosis, 195 (1):e125-e133.
2007 Morrow D, Sweeney C, Guha S, Walshe T, O'Brien C, Walls D, Redmond EM, Cahill PA. (2007) 'Notch signaling and vascular cell fate--how vascular cells respond to stress. Wien Klin Wochenschr'. 119 :7-10.
2007 Connell, Paul and Walshe, Tony and Ferguson, Gail and Gao, Wei and O'Brien, Colm and Cahill, Paul A. (2007) 'Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells'. 14 (1):17-24.
2007 Guha, Shaunta T. and Murphy, Ronan and Walls, Dermot and Redmond, Eileen M. and Cahill, Paul A. (2007) 'Inhibition of glycogen synthase kinase-3 beta decreases vascular smooth muscle cell growth in vitro through modulation of notch signaling'. 27 (6).
2007 Killeen, Maria T. and Murphy, Ronan P. and Cahill, Paul A. and Cummins, Philip M. (2007) 'Cyclic strain of vascular endothelial cells reduces vascular smooth muscle cell proliferation, possibly via an MMP-2-dependent mechanism'. 27 (6).
2007 Morrow, David and Cullen, John P. and Cahill, Paul A. and Redmond, Eileen M. (2007) 'Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: Role in angiogenesis'. 27 (6).
2007 Morrow, D. and Sweeney, C. and Guha, S. and Walshe, T. and O'Brien, C. and Walls, D. and Redmond, E. M. and Cahill, P. A. (2007) 'Notch signaling and vascular cell fate - how vascular cells respond to stress'. 119 (1):7-10.
2007 Cullen, John P. and Morrow, David and Jin, Ying and Curley, Brian and Robinson, Alex and Sitzmann, James V. and Cahill, Paul A. and Redmond, Eileen M. (2007) 'Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion'. 44 (1):75-84.
2007 Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O'Brien C, Cahill PA. (2007) 'High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway. J Mol Cell Cardiol'. 42 :609-619.
2007 Colgan OC, Ferguson G, Collins NT, Murphy RP, Meade G, Cahill PA, Cummins PM. (2007) 'Regulation of bovine brain microvascular endothelial tight junction assembly and barrier function by laminar shear stress. Am J Physiol Heart Circ Physiol'. 292 :H3190-H3197.
2007 Cullen JP, Morrow D, Jin Y, Curley B, Robinson A, Sitzmann JV, Cahill PA, Redmond EM. (2007) 'Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion. J Vasc Res'. 44 :75-84.
2007 Morrow D, Sweeney C, Birney YA, Guha S, Collins N, Cummins PM, Murphy R, Walls D, Redmond EM, Cahill PA. (2007) 'Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo. Am J Physiol Cell Physiol'. 292 :c488-c496.
2007 Cullen JP, Morrow D, Jin Y, von Offenberg Sweeney N, Sitzmann JV, Cahill PA, Redmond EM. (2007) 'Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocy. Atherosclerosis'. 195 :e125-e133.
2007 Gao, Wei and Ferguson, Gail and Connell, Paul and Walshe, Tony and Murphy, Ronan and Birney, Yvonne A. and O'Brien, Colm and Cahill, Paul A. (2007) 'High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1 alpha-dependent pathway'. 42 (3):609-619.
2006 Pegman, Pamela M. and Smith, Sinad M. and D'Souza, Brendan N. and Loughran, Sinead T. and Maier, Sabine and Kempkes, Bettina and Cahill, Paul A. and Simmons, Matthew J. and Gelinas, Celine and Walls, Dermot (2006) 'Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBFI/RBPJ kappa-Dependent pathway'. 80 (16):8133-8144.
2006 Sweeney, C. H. and Cahill, P. A. and Bresnihan, B. and FitzGerald, O. and Fearon, U. and Veale, D. J. (2006) 'A role for the survivin and notch signalling pathways in blood vessel maturation and synovial hyperplasia in rheumatoid arthritis'. 65 (2):112-113.
2006 Colgan, OC and Collins, NT and Birney, YA and Ferguson, G and Cahill, PA and Cummins, PM (2006) 'Shear stress regulates microvascular endothelial occludin and ZO-1 and increases tight junction formation'. 26 (5).
2006 Cullen, JP and Cahill, PA and Redmond, EM (2006) 'Cyclic strain regulates the plasminogen activator system in human umbilical venous endothelial cells'. 26 (5).
2006 Cullen, JP and Jin, Y and Von Offenberg, N and Cahill, PA and Redmond, EM (2006) 'Inhibition of chemokine receptor CCR2 mRNA expression and binding by resveratrol; Role of nitric oxide and mitogen activated protein kinase'. 26 (5).
2006 Collins NT, Cummins PM, Colgan OC, Ferguson G, Birney YA, Murphy RP, Meade G, Cahill PA. (2006) 'Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly and function. Arterioscler Thromb Vasc Biol'. 26 :62-68.
2006 Gao, W and Murphy, RP and Ferguson, G and Cahill, PA (2006) 'Hyperglycaemia alters hypoxia-induced cell fate decisions in bovine aortic endothelial cells'. 26 (5).
2006 Collins, NT and Cummins, PM and Colgan, OC and Ferguson, G and Birney, YA and Murphy, RP and Meade, G and Cahill, PA (2006) 'Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1 - Influence on intercellular tight junction assembly and function'. 26 (1):62-68.
2006 Tobin, NP and Cummins, PM and Henehan, G and Cahill, PA (2006) 'Helicobacter pylori outer membrane protein effects vascular endothelial cell fate decisions in vitro'. 26 (5).
2006 Moran, Diarmuid M. and Koniaris, Leonidas G. and Jablonski, Elizabeth M. and Cahill, Paul A. and Halberstadt, Craig R. and McKillop, Iain H. (2006) 'Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression'. 15 (8-9):785-798.
2006 Fitzpatrick, PA and Killeen, MT and Birney, YA and Glucksman, MJ and Cahill, PA and Cummins, PM (2006) 'Shear stress regulation of NEP is mediated via reactive oxygen species in endothelial cells'. 26 (5).
2005 Birney, YA and Sweeney, CH and Morrow, D and Guha, S and Cummins, PM and Walls, D and Redmond, EM and Cahill, PA (2005) 'Vascular smooth muscle cell migration \& notch signalling'. 112 (17, S).
2005 Walshe, TE and O'Brien, C and Cahill, PA (2005) 'Notch signaling in co-cultured endothelial \& pericyte cells exposed to pulsatile flow'. 46 (S).
2005 Morrow, D and Sweeney, C and Birney, YA and Cummins, PM and Guha, S and Murphy, R and Walls, D and Redmond, EM and Cahill, PA (2005) 'Sonic hedgehog regulates vascular smooth muscle cell fate in vitro through VEGF activation of notch signaling'. 112 (17, S).
2005 Sweeney, C and Cahill, PA and Mullan, R and Connolly, M and Bresnihan, B and FitzGerald, O and Fearon, U and Veale, DJ (2005) 'A role for the Survivin and Notch signaling pathways in blood vessel maturation and synovial hyperplasia in rheumatoid arthritis'. 52 (9, S).
2005 Cullen, JP and Sayeed, S and Kim, Y and Theodorakis, NG and Sitzmann, JV and Cahill, PA and Redmond, EM (2005) 'Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type I, matrix metalloproteinase-2 and-9'. 94 (3):639-645.
2005 Cotter, EJ and Fitzpatrick, PA and Birney, Y and Wu, TJ and Glucksman, MJ and Cahill, PA and Cummins, PM (2005) 'Cyclic strain induces changes in EP24.15 subcellular localization, and peptide cleavage; Possible implications for endothelial cell fate decisions'. 25 (5).
2005 Cullen, JP and Jin, Y and Sweeney, NV and Sitzmann, JV and Cahill, PA and Redmond, EM (2005) 'Resveratrol downregulates CC chemokine receptor 2 binding and expression on THP-1 monocytes'. 25 (5).
2005 Cullen, JP and Sweeney, NV and Cahill, PA and Redmond, EM (2005) 'C-reactive protein-mediated inhibition of endothelial cell PAI-1 production is prevented by ethanol and resveratrol'. 25 (5).
2005 Fitzpatrick, PA and Cotter, EJ and Birney, YA and Glucksman, MJ and Cahill, PA and Cummins, PM and Franklin, R (2005) 'Expression of Thermolysin-Like zinc metalloendopeptidases in vascular endothelial cells is regulated by shear stress and reactive oxygen species'. 25 (5).
2005 Gao, W and Murphy, RP and Ferguson, G and Cahill, PA (2005) 'High glucose concentrations alter hypoxia-induced cell fate decisions in bovine aortic smooth muscle cells'. 25 (5).
2005 Morrow, D and Guha, ST and Birney, Y and Sweeney, C and Cummins, P and Walls, D and Redmond, E and Cahill, PA (2005) 'Hedgehog regulation of Notch signaling in vascular smooth muscle cells in vitro'. 25 (5).
2005 Sweeney, NV and Cullen, JP and Cahill, PA and Redmond, EM (2005) 'Cyclic strain-induced MMP-9 activity in bovine aortic endothelial cells is mediated via a Notch/CBF-1 dependent pathway'. 25 (5).
2005 Sweeney, NV and Cummins, PM and Cotter, EJ and Fitzpatrick, PA and Birney, YA and Redmond, EM and Cahill, PA (2005) 'Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation'. 329 (2):573-582.
2005 Moran, DM and Mayes, N and Koniaris, LG and Cahill, PA and McKillop, IH (2005) 'Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma'. 25 (2):445-457.
2005 Morrow, D and Sweeney, C and Birney, YA and Cummins, PM and Walls, D and Redmond, EM and Cahill, PA (2005) 'Cyclic strain inhibits notch receptor signaling in vascular smooth muscle cells in vitro'. 96 (5):567-575.
2005 Walshe, TE and Ferguson, G and Connell, P and O'Brien, C and Cahill, PA (2005) 'Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature'. 46 (1):375-382.
2005 Collins, NT and Cummins, PM and Colgan, OC and Birney, YA and Ferguson, G and Murphy, RP and Cahill, PA (2005) 'Cyclic strain regulates occludin and Z0-1 expression, phosphorylation and localisation in bovine aortic endothelial cells'. 112 (17, S).
2004 Coen, PM and Cummins, PM and Birney, YA and Devery, R and Cahill, PA (2004) 'Modulatiori of nitric oxide and 6-keto-prostaglandin F-1 alpha production in bovine aortic endothelial cells by conjugated linoleic acid'. 11 (3-4):211-220.
2004 Connell, PP and O'Brien, CJ and Cahill, PA (2004) 'High Glucose Suppresses Pulsatile flow induced ppEnos protein expression and eNOS activity'. 45 (2).
2004 Cotter, EJ and Sweeney, NV and Coen, PM and Birney, YA and Glucksman, MJ and Cahill, PA and Cummins, PM (2004) 'Regulation of endopeptidases EC3.4.24.15 and EC3.4.24.16 in vascular endothelial cells by cyclic strain: Role of Gi protein signaling'. 24 (3):457-463.
2004 Birney, YA and Sweeney, CH and Cappadona, CR and Sitzmann, JV and Cummins, PM and Redmond, EM and Cahill, PA (2004) 'Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner'. 41 (4):364-374.
2004 Cullen, JP and Nicholl, SM and Sayeed, S and Sitzmann, JV and Okada, SS and Cahill, PA and Redmond, EM (2004) 'Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration'. 114 (1):57-65.
2004 Sweeney, C and Morrow, D and Birney, YA and Coyle, S and Hennessy, C and Scheller, A and Cummins, PM and Walls, D and Redmond, EM and Cahill, PA (2004) 'Notch 1 and 3 receptors modulate vascular smooth muscle cell growth, apoptosis and migration via a CBF-1/RBP-Jk dependent pathway'. 18 (10).
2004 Collins, NT and Colgan, OC and Ferguson-Welsby, G and Murphy, RP and Cummins, PM and Cahill, PA (2004) 'Cyclic strain regulates occludin and ZO-1 expression, phosphorylation, and localization in bovine aortic endothelial cells (BAEC)'. 110 (17, S).
2004 Cummins, PM and Cotter, EJ and Cahill, PA (2004) 'Hemodynamic regulation of metallopeptidases within the vasculature'. 11 (5):433-442.
2004 Sweeney, NV and Cummins, PM and Birney, YA and Cullen, JP and Redmond, EM and Cahill, PA (2004) 'Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity'. 63 (4):625-634.
2004 Sweeney, NV and Cummins, PM and Birney, YA and Redmond, EM and Cahill, PA (2004) 'Cyclic strain-induced endothelial MMP-2: role in vascular smooth muscle cell migration'. 320 (2):325-333.
2004 Morrow, D and Sweeney, CH and Birney, YA and Cummins, PM and Walls, D and Redmond, EM and Cahill, PA (2004) 'The role of notch target genes, HRT-1, HRT-2, and HRT-3, in determining vascular smooth muscle cell proliferation and apoptosis'. 110 (17, S).
2003 Kim, SI and Grum-Tokars, V and Swanson, TA and Cotter, EJ and Cahill, PA and Roberts, JL and Cummins, PM and Glucksman, MJ (2003) 'Novel roles of neuropeptide processing enzymes: EC3.4.24.15 in the neurome'. 74 (3):456-467.
2003 Birney, Y and Redmond, EM and Sitzmann, JV and Cahill, PA (2003) 'Eicosanoids in cirrhosis and portal hypertension'. 72 (1-2):3-18.
2003 Scheller, A and Morrow, DJ and Sweeney, CH and Walls, D and Cummins, PM and Redmond, EM and Cahill, PA (2003) 'Notch signalling and vascular smooth muscle cell differentiation'. 23 (5).
2003 Morrow, D and Sweeney, C and Scheller, A and Walls, D and Cummins, P and Cahill, PA (2003) 'Notch receptor ligand-signalling role in Vascular smooth muscle cell proliferation'. 17 (4, 1, S).
2003 Theodorakis, NG and Wang, YN and Skill, NJ and Metz, MA and Cahill, PA and Redmond, EM and Sitzmann, JV (2003) 'The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: Studies in gene-knockout mice'. 124 (5):1500-1508.
2003 Coen, PM and Cummins, PM and Devery, R and Cahill, PA (2003) 'The effects of conjugated linoleic acid on nitric oxide synthase and cyclooxygenase expression and activity in vascular endothelial cells'. 17 (5, 2, S).
2003 Cotter, EJ and Cahill, PA and Cummins, PM (2003) 'Cyclic strain modulates activity of endopeptidases EC 3.4.24.15 and EC 3.4.24.16 in vascular endothelial cells'. 17 (4, 1, S).
2003 Sweeney, CH and Morrow, DJ and Scheller, A and Birney, YA and Walls, D and Redmond, EM and Cahill, PA (2003) 'Notch signaling and cyclic strain induced changes in vascular cell fate'. 23 (5).
2002 Sweeney, C;Hennessy, C;Coyle, S;Walls, D;Cahill, P (2002) 'The role of Notch Signalling in aortic vascular smooth muscle cells'. FASEB Journal, 16 .
2002 Sweeney, N and Cummins, P and Cahill, PA (2002) 'Role of the SHC/MAP kinase pathway and Gi alpha proteins in cyclic strain induced increases in pro-MMP2 secretion'. 106 (19, S).
2002 Price, JA and Kovach, SJ and Johnson, T and Koniaris, LG and Cahill, PA and Sitzmann, JV and McKillop, LH (2002) 'Insulin-like growth factor I is a comitogen for hepatocyte growth factor in a rat model of hepatocellular carcinoma'. 36 (5):1089-1097.
2002 Sweeney, NV and Birney, YA and Cummins, P and Cahill, PA (2002) 'Cyclic Strain Induces Pro-MMP2 release from bovine aortic endothelial cells via a Gi alpha protein-independent, MAP kinase-dependent pathway'. 16 (4, 1).
2002 Knight, AW and Goddard, NJ and Billinton, N and Cahill, PA and Walmsley, RM (2002) 'Fluorescence polarization discriminates green fluorescent protein from interfering auto fluorescence in a microplate assay for genotoxicity'. 51 (2):165-177.
2002 Birney, YA and Sweeney, C and Cappadona, C and Redmond, EM and Sitzmann, JV and Cahill, PA (2002) 'Pulse pressure-induced vascular smooth muscle cell apoptosis'. 16 (4, 1).
2002 Cullen, JP and Sayeed, S and Sawai, RS and Theodorakis, NG and Cahill, PA and Sitzmann, JV and Redmond, EM (2002) 'Pulsatile flow-induced angiogenesis - Role of G(i) Subunits'. 22 (10):1610-1616.
2001 Coyle, S and Sweeney, C and Hennessy, C and Walls, D and Cahill, PA (2001) 'The role of Notch signaling in aortic vascular smooth muscle cells'. 104 (17, S).
2001 Cummins, PM and Coen, PM and Cahill, PA (2001) 'Regulation of endopeptidase EC 3.4.24.15 expression in vascular endothelial cells by mechanical forces'. 104 (17, S).
2001 Theodorakis, NG and Wang, YN and Redmond, EM and Cahill, PA and Sitzmann, JV (2001) 'The role of nitric oxide synthase isoforms in the development of portal hypertension: Studies in gene-deficient mice'. 34 (4, 2, S).
2001 Cahill, PA and Redmond, EM and Sitzmann, JV (2001) 'Endothelial dysfunction in cirrhosis and portal hypertension'. 89 (3):273-293.
2000 Redmond, EM and Sitzmann, JV and Cahill, PA (2000) 'Potential mechanisms for cardiovascular protective effect of ethanol'. 21 (5):385-390.
1999 Cappadona, C and Redmond, EM and Theodorakis, NG and McKillop, IH and Hendrickson, R and Chhabra, A and Sitzmann, JV and Cahill, PA (1999) 'Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro'. 13 (5, 2, S).
1999 Kouretas, PC and Kim, YD and Cahill, PA and Myers, AK and To, LN and Wang, YN and Sitzmann, JV and Hannan, RL (1999) 'Nonanticoagulant heparin prevents coronary endothelial dysfunction after brief ischemia-reperfusion injury in the dog'. 99 (8):1062-1068.
1999 Cahill, PA and Ambrose, CA and Egan, ME (1999) 'The role of CFTR-nucleotide binding fold 2 in CFTR regulation of K-atp channels'. 159 (3, S).
1999 Hendrickson, RJ and Cappadona, C and Yankah, EN and Sitzmann, JV and Cahill, PA and Redmond, EM (1999) 'Sustained pulsatile flow regulates endothelial nitric oxide synthase and cyclooxygenase expression in co-cultured vascular endothelial and smooth muscle cells'. 31 (3):619-629.
1999 Cahill, PA (1999) 'Vasoconstrictor responsiveness of portal hypertensive vessels'. 96 (1):3-4.
1999 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1999) 'The role of cAMP-MAPK signalling in the regulation of human hepatocellular carcinoma growth in vitro'. 11 (12):1393-1399.
1999 Cappadona, C and Redmond, EM and Theodorakis, NG and McKillop, IH and Hendrickson, R and Chhabra, A and Sitzmann, JV and Cahill, PA (1999) 'Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro'. 250 (1):174-186.
1999 McKillop, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1999) 'Inhibitory guanine nucleotide regulatory protein activation of mitogen-activated protein kinase in experimental hepatocellular carcinoma in vitro'. 11 (7):761-768.
1998 Hendrickson, RJ and Cahill, PA and McKillop, IH and Sitzmann, JV and Redmond, EM (1998) 'Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro'. 362 (2-3):251-259.
1998 Kouretas, PC and Hannan, RL and Kapur, NK and Hendrickson, R and Redmond, EM and Myers, AK and Kim, YD and Cahill, PA and Sitzmann, JV (1998) 'Non-anticoagulant heparin increases endothelial nitric oxide synthase activity: Role of inhibitory guanine nucleotide proteins'. 30 (12):2669-2682.
1998 Redmond, EM and Cahill, PA and Sitzmann, JV and Okada, SS (1998) 'Endothelial cells inhibit pulsatile flow-induced smooth muscle cell migration by a mechanism involving plasminogen activator inhibitor-1'. 98 (17, S).
1998 Kouretas, PC and Kim, YD and Cahill, PA and Myers, AK and To, LN and Wang, YN and Wallace, RB and Kron, IL and Hannan, RL (1998) 'Heparin preserves nitric oxide activity in coronary endothelium during ischemia-reperfusion injury'. 66 (4):1210-1215.
1998 Schmidt, CM and Mckillop, IH and Cahill, PA and Sitzmann, JV (1998) 'G-protein stimulated mitogenesis in human hepatocellular carcinoma'. 28 (4, 2, S).
1998 Cahill, PA and Hou, MC and Hendrickson, R and Wang, YN and Zhang, SM and Redmond, EM and Sitzmann, JV (1998) 'Increased expression of endothelin receptors in the vasculature of portal hypertensive rats: Role in splanchnic hemodynamics'. 28 (2):396-403.
1998 Hou, MC and Cahill, PA and Zhang, SM and Wang, YN and Hendrickson, RJ and Redmond, EM and Sitzmann, JV (1998) 'Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: Role in the hyperdynamic circulation'. 27 (1):20-27.
1998 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1998) 'Inhibitory guanine nucleotide proteins regulate human hepatocellular carcinoma growth via a MAPK pathway'. 114 (4, 2, S).
1998 Hendrickson, R and Redmond, EM and Yankah, E and Cahill, PA and Sitzmann, JV (1998) 'Pulsatile flow regulates cyclooxygenase in vascular smooth muscle cells co-cultured with endothelial cells'. 12 (4, 1, S).
1998 McKillop, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1998) 'G-protein activation of mitogen activated protein kinases in hepatocellular carcinoma'. 12 (4, 1, S).
1998 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1998) 'Functionally significant Gq alpha-linked MAPK pathway in experimental hepatocellular carcinoma'. 12 (4, 1, S).
1998 Kouretas, PC and Myers, AK and Kim, YD and Cahill, PA and Myers, JL and Wang, YN and Sitzmann, JV and Wallace, RB and Hannan, RL (1998) 'Heparin and nonanticoagulant heparin preserve regional myocardial contractility after ischemia-reperfusion injury: Role of nitric oxide'. 115 (2):440-448.
1998 Redmond, EM and Cahill, PA and Sitzmann, JV (1998) 'Flow-mediated regulation of G-protein expression in cocultured vascular smooth muscle and endothelial cells'. 18 (1):75-83.
1997 McKillop, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1997) 'Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma'. 26 (6):1484-1491.
1997 Cahill, PA (1997) 'Quantitative discrimination of ANF receptor subtypes in portal hypertension - Reply'. 26 (2).
1997 Redmond, EM and Cahill, PA and Sitzmann, JV (1997) 'Flow-mediated regulation of endothelin receptors in cocultured vascular smooth muscle cells: An endothelium-dependent effect'. 34 (6):425-435.
1997 Redmond, EM and Cahill, PA and Sitzmann, JV and Okada, SS (1997) 'Flow-induced changes in smooth muscle cell urokinase gene expression and subsequent alteration in migration'. 96 (8, S).
1997 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1997) 'Functionally significant Gi-protein linked MAPK pathway in primary human hepatocellular carcinoma'. 26 (4, 2, S).
1997 McKillop, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1997) 'Selective changes in G-protein expression and Gi-protein linked mitogenesis in experimental hepatocellular carcinoma following chronic ethanol exposure'. 26 (4, 2, S).
1997 Hendrickson, RJ and Redmond, EM and Cahill, PA and Sitzmann, JV (1997) 'Ethanol enhances flow-induced nitric oxide synthase activity in cultured endothelial cells'. 26 (4, 2, S).
1997 Hendrickson, R and Wang, YN and Hou, MC and Zhang, S and Redmond, EM and Cahill, PA and Sitzmann, JV (1997) 'Altered vascular response to endothelin in portal hypertensive rats'. 26 (4, 2, S).
1997 Sabharwal, P and McKillop, IH and Cahill, PA and Sitzmann, JV (1997) 'Altered cytokine expression and cellular immunity following cryoablation in experimental hepatocellular carcinoma'. 26 (4, 2, S).
1997 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1997) 'Increased MAPK expression and activity in primary human hepatocellular carcinoma'. 236 (1):54-58.
1997 Mckillop, IH and Johnson, T and Sabharwal, P and Schmidt, CM and Cahill, PA and Sitzmann, JV (1997) 'Hepatic insulin-like growth factor-I (IGF-I) receptor and mRNA expression in experimental hepatocellular carcinoma (HCC)'. 11 (3).
1997 Kouretas, PC and Cahill, PA and Myers, AK and Redmond, EM and Kim, YD and Hendrickson, RJ and Sitzmann, JV and Hannan, RL (1997) 'Heparin and non-anticoagulant heparin regulate nitric oxide synthase activity in bovine aortic endothelial cells'. 11 (3).
1997 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1997) 'Alterations in guanine nucleotide regulatory protein expression and activity in human hepatocellular carcinoma'. 26 (5):1189-1194.
1996 Schmidt, CM and Cahill, PA and McKillop, IH and Redmond, EM and Sitzmann, JV (1996) 'Increased expression of guanine nucleotide regulatory protein Gq alpha/G11 in hepatocellular carcinoma (HCC)'. 10 (3).
1996 McKillop, L and Cahill, PA and Sitzmann, JV (1996) 'Activation of Gi alpha proteins stimulates c-myc expression and cellular proliferation in hepatocellular carcinoma'. 10 (3).
1996 Cahill, PA and Redmond, EM and Sitzmann, JV (1996) 'Regulation of Gi alpha-protein expression by nitric oxide in bovine aortic endothelial cells'. 10 (3).
1996 DeMaio, A and Gingalewski, C and Sitzmann, JV and Cahill, PA (1996) 'Expression of inducible nitric oxide synthase in rat lung following regional hepatic ischemia reperfusion injury'. 10 (3).
1996 Redmond, EM and Cahill, PA and Hodges, R and Zhang, SM and Sitzmann, JV (1996) 'Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells'. 166 (3):469-479.
1996 Wu, YP and Cahill, PA and Sitzmann, JV (1996) 'Decreased angiotensin II receptors mediate decreased vascular response in hepatocellular cancer'. 223 (2):225-231.
1996 Cahill, PA and Redmond, EM and Wu, YP and Sitzmann, JV (1996) 'Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits'. 24 (2):185-193.
1996 McKillop, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1996) 'Mitogen activated protein kinase (MAPK) expression in experimental hepatocellular carcinoma (HCC)'. 7 (S).
1996 Redmond, EM and Cahill, PA and Sitzmann, JV (1996) 'Shear stress-mediated pressor hormone receptor regulation in vascular smooth muscle cells co-cultured with endothelial cells'. 94 (8, S).
1996 Hou, MC and Zhang, S and Redmond, EM and Cahill, PA and Sitzmann, JV (1996) 'Enhanced G-protein-induced relaxation in portal hypertensive rats: Role of nitric oxide'. 24 (4, 2, S).
1996 Hou, MC and Zhang, S and Redmond, EM and Cahill, PA and Sitzmann, JV (1996) 'Effect of chronic nitric oxide synthase and cyclooxygenase blockade on splanchnic hemodynamics in portal hypertensive rats'. 24 (4, 2, S).
1996 Cahill, PA and Hou, MC and Zhang, S and Redmond, EM and Sitzmann, JV (1996) 'Increased expression of endothelin receptors in hyperemic vessels from portal hypertensive rats'. 24 (4, 2, S).
1996 Cahill, PA and Redmond, EM and Hou, MC and Zhang, S and Sitzmann, JV (1996) 'Enhanced cyclooxygenase I expression in portal hypertensive rats'. 24 (4, 2, S).
1996 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1996) 'Increased expression of guanine nucleotide regulatory protein (G-protein) G(11) in hepatocellular carcinoma (HCC)'. 24 (4, 2, S).
1996 Cahill, PA and Redmond, EM and Hodges, R and Zhang, SM and Sitzmann, JV (1996) 'Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats'. 25 (3):370-378.
1996 Redmond, EM and Cahill, PA and Sitzmann, JV (1996) 'Shear stress-mediated regulation of G-protein expression in co-cultured vascular smooth muscle cells and endothelial cells'. 10 (6).
1996 McKillip, IH and Schmidt, CM and Cahill, PA and Sitzmann, JV (1996) 'Ethanol upregulates Gi alpha protein expression in an experimental hepatoma line; Possible role in the progression of HCC growth'. 10 (6).
1996 Schmidt, CM and McKillop, IH and Cahill, PA and Sitzmann, JV (1996) 'Increased expression of mitogen activated protein kinase pathway in rat and human hepatocellular carcinoma'. 10 (6).
1996 Cahill, PA and Rohlfing, CM (1996) 'Theoretical studies of derivatized buckyballs and buckytubes'. 52 (14):5247-5256.
1996 Redmond, EM and Cahill, PA and Sitzmann, JV (1996) 'Shear stress-mediated regulation of G-protein expression in vascular smooth muscle cells co-cultured with endothelial cells'. 10 (3).
1996 Sabharwal, P and McKillop, I and DeMaio, A and Cahill, PA and Sitzmann, V (1996) 'Heat-shock protein expression (HSP-72) in rat hepatocellular carcinoma following cryoablation'. 10 (3).
1995 MCKILLOP, I and WU, YP and CAHILL, PA and SITZMANN, JV (1995) 'REGULATION OF GI-ALPHA-PROTEIN EXPRESSION IN HEPATOCELLULAR CARCINOMA-POSSIBLE ROLE IN TUMOR-GROWTH'. 22 (4, 2, S).
1995 CAHILL, PA and REDMOND, EM and FOSTER, C and SITZMANN, JV (1995) 'NITRIC-OXIDE REGULATES ANGIOTENSIN-II RECEPTORS IN VASCULAR SMOOTH-MUSCLE CELLS'. 288 (2):219-229.
1995 REDMOND, EM and CAHILL, PA and SITZMANN, JV (1995) 'NITRIC-OXIDE PREFERENTIALLY UP-REGULATES THE ENDOTHELIN ET(A) RECEPTOR SUBTYPE IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS - ROLE OF CAMP-/CGMP-DEPENDENT PROTEIN-KINASES'. 22 (4, 2, S).
1995 REDMOND, EM and CAHILL, PA and SITZMANN, JV (1995) 'PERFUSED TRANSCAPILLARY SMOOTH-MUSCLE AND ENDOTHELIAL-CELL COCULTURE - A NOVEL IN-VITRO MODEL'. 31 (8):601-609.
1995 CAHILL, PA and SITZMANN, JV (1995) 'NITRIC-OXIDE AND PORTAL-HYPERTENSION'. 23 (3):355-356.
1995 SITZMANN, JV and WU, YP and AGUILERA, G and CAHILL, PA and BURNS, RC (1995) 'LOSS OF ANGIOTENSIN-II RECEPTORS IN PORTAL HYPERTENSIVE RABBITS'. 22 (2):559-564.
1995 CAHILL, PA and FOSTER, G and REDMOND, EM and GINGALEWSKI, C and WU, YP and SITZMANN, JV (1995) 'ENHANCED NITRIC-OXIDE SYNTHASE ACTIVITY IN PORTAL HYPERTENSIVE RABBITS'. 22 (2):598-606.
1995 CAHILL, PA and REDMOND, EM and HODGES, R and ZHANG, SM and SITZMANN, JV (1995) 'ALTERED EXPRESSION OF G-ALPHA-Q IN THE HYPEREMIC VASCULATURE OF PORTAL HYPERTENSIVE RATS'. 108 (4, S).
1995 HODGES, R and ZHANG, S and CAHILL, PA and REDMOND, EM and SITZMANN, JV (1995) 'VASCULAR HYPERRESPONSIVENESS TO ENDOTHELIN IN THE HYPEREMIC VASCULATURE OF PORTAL HYPERTENSIVE RATS'. 108 (4, S).
1995 REDMOND, EM and HODGES, R and ZHANG, S and CAHILL, PA and SITZMANN, JV (1995) 'NITRIC OXIDE-MEDIATED VASCULAR HYPERRESPONSIVENESS TO ENDOTHELIN'. 108 (4, S).
1995 SABHARWAL, P and WU, Y and CAHILL, PA and SITZMANN, JV (1995) 'DIFFERENTIAL SYMPATHOADRENAL ACTIVITY FOLLOWING HEMORRHAGIC-SHOCK IN PORTAL HYPERTENSIVE RABBITS'. 108 (4, S).
1995 CAHILL, PA and REDMOND, EM and SITZMANN, JV (1995) 'REGULATION OF G-PROTEIN EXPRESSION BY NITRIC-OXIDE IN RAT VASCULAR SMOOTH-MUSCLE CELLS'. 9 (4, 2).
1995 HODGES, R and ZHANG, S and CAHILL, PA and REDMOND, EM and SITZMANN, JV (1995) 'VASCULAR HYPERRESPONSIVENESS TO NOREPINEPHRINE IN THE HYPEREMIC VASCULATURE OF PORTAL HYPERTENSIVE RATS'. 9 (4, 2).
1995 REDMOND, EM and CAHILL, PA and SITZMANN, JV (1995) 'PERFUSED TRANSCAPILLARY SMOOTH-MUSCLE AND ENDOTHELIAL-CELL GO-CULTURE - A NOVEL IN-VITRO MODEL'. 9 (3, 1).
1995 SABHARWAL, P and CAHILL, PA and SITZMANN, JV (1995) 'THE EFFECT OF HEPATOCELLULAR-CARCINOMA ON CELLULAR-IMMUNITY IN RODENTS'. 9 (3, 1).
1995 CAHILL, PA and REDMOND, EM and HODGES, R and ZHANG, SM and SITZMANN, JV (1995) 'LACK OF INDUCIBLE NOS (INOS) EXPRESSION WITHIN THE HYPEREMIC VASCULATURE OF PORTAL HYPERTENSIVE RATS'. 22 (4, 2, S).
1994 NIYAZYMBETOV, ME and EVANS, DH and LERKE, SA and CAHILL, PA and HENDERSON, CC (1994) 'STUDY OF ACID-BASE AND REDOX EQUILIBRIA FOR THE C-60 C60H2 SYSTEM IN DIMETHYL-SULFOXIDE SOLVENT'. 98 (49):13093-13098.
1994 CAHILL, PA and FOSTER, C and WU, YP and STIZMANN, JV (1994) 'INCREASED G-PROTEIN EXPRESSION IN THE HYPEREMIC VASCULATURE OF PORTAL HYPERTENSIVE RABBITS'. 20 (4, 2).
1994 REDMOND, EM and CAHILL, PA and SITZMANN, JV (1994) 'REGULATION OF ENDOTHELIN RECEPTORS BY NITRIC-OXIDE IN CULTURED RAT VASCULAR SMOOTH-MUSCLE CELLS'. 20 (4, 2).
1994 REDMOND, EM and CAHILL, PA and MARTIN, LD and WETZEL, RC (1994) 'ENDOCARDIAL AND VASCULAR ENDOTHELIAL NITRIC-OXIDE SYNTHASE ACTIVITY - NO EFFECT OF 17-BETA-ESTRADIOL'. 8 (4).
1994 CAHILL, PA and FOSTER, CL and WU, Y and SITZMANN, JV (1994) 'REGULATION OF ATRIAL-NATRIURETIC-PEPTIDE HORMONE RECEPTORS IN PORTAL-HYPERTENSION'. 8 (5).
1994 SITZMANN, JV and CAHILL, PA (1994) 'REGULATION OF ANGIOTENSIN-II RECEPTORS BY NITRIC-OXIDE IN RAT VASCULAR SMOOTH-MUSCLE CELLS'. 8 (5).
1994 WU, Y and CAHILL, PA and SITZMANN, JV (1994) 'ALTERED G-PROTEIN EXPRESSION AND ADENYLATE-CYCLASE ACTIVITY IN HEPATOMA'. 8 (5).
1994 CAHILL, PA and WU, YP and SITZMANN, JV (1994) 'ALTERED ADENYLYL-CYCLASE ACTIVITIES AND G-PROTEIN ABNORMALITIES IN PORTAL HYPERTENSIVE RABBITS'. 93 (6):2691-2700.
1993 CAHILL, PA and WU, YP and SITZMANN, JV (1993) 'NITRIC-OXIDE SYNTHASE ACTIVITY IN PORTAL-HYPERTENSION'. 18 (4, 2).
1993 CAHILL, PA and HASSID, A (1993) 'DIFFERENTIAL ANTIMITOGENIC EFFECTIVENESS OF ATRIAL NATRIURETIC PEPTIDES IN PRIMARY VERSUS SUBCULTURED RAT AORTIC SMOOTH-MUSCLE CELLS - RELATIONSHIP TO EXPRESSION OF ANF-C RECEPTORS'. 154 (1):28-38.
1993 CAHILL, PA and WU, YP and SITZMANN, JV (1993) 'ADENYLATE-CYCLASE ACTIVITIES OF VASCULAR SMOOTH-MUSCLE AND ADRENAL IN PORTAL HYPERTENSIVE RABBITS'. 7 (4, 2).
1993 WU, YP and CAHILL, PA and SITZMANN, JV (1993) 'DECREASED ANGIOTENSIN-II RECEPTORS MEDIATE DECREASED VASCULAR-RESPONSE IN HEPATOMA'. 18 (4, 2).
1991 CAHILL, PA and HASSID, A (1991) 'CLEARANCE RECEPTOR-BINDING ATRIAL NATRIURETIC PEPTIDES INHIBIT MITOGENESIS AND PROLIFERATION OF RAT AORTIC SMOOTH-MUSCLE CELLS'. 179 (3):1606-1613.
1991 HASSID, A and CAHILL, PA and PATEL, TB (1991) 'INHIBITION OF RAT AORTIC SMOOTH-MUSCLE CELL MITOGENESIS BY ATRIAL-NATRIURETIC-PEPTIDE IS MEDIATED BY A CYCLIC GMP-INDEPENDENT MECHANISM VIA THE ANF CLEARANCE RECEPTOR'. 5 (6, 3).
1991 CAHILL, PA and HASSID, A (1991) 'DIFFERENTIAL ANTIMITOGENIC ACTIONS OF ATRIAL NATRIURETIC PEPTIDES IN PRIMARY VERSUS SUBCULTURED RAT AORTIC SMOOTH-MUSCLE CELLS STIMULATED BY SERUM OR DEFINED GROWTH-FACTORS'. 5 (6, 3).
1990 REDMOND, EM and CAHILL, PA and KEENAN, AK (1990) 'ATRIAL-NATRIURETIC-FACTOR RECOGNIZES 2 RECEPTOR SUBTYPES IN ENDOTHELIAL-CELLS CULTURED FROM BOVINE PULMONARY-ARTERY'. 269 (1):157-162.
1990 CAHILL, PA and REDMOND, EM and KEENAN, AK (1990) 'VASCULAR ATRIAL-NATRIURETIC-FACTOR RECEPTOR SUBTYPES ARE NOT INDEPENDENTLY REGULATED BY ATRIAL PEPTIDES'. 265 (35):21896-21906.
1988 CAHILL, PA and FALLER, D and KEENAN, AK (1988) 'RECEPTOR-BINDING AND INTERNALISATION OF ATRIAL NATRIURETIC FACTOR IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS'. 95 (S).

Conference Publication

Year Publication
2020 King D.;Cahill P.;Kernan D.;Julius A.;Canning D.;Healy K.;Simonsen U.;Ducrée J. (2020) 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 Optical real-time monitoring of endothelial expression markers at single-cell level enabled by a centrifugal microfluidic platform
2015 Doyle A.;Redmond E.;Gillespie D.;Knight P.;Cullen J.;Cahill P.;Morrow D. (2015) Journal of Vascular Surgery Differential expression of Hedgehog/Notch and transforming growth factor-β in human abdominal aortic aneurysms
1997 Hubbard, SF and Petschek, RG and Singer, KD and DSidocky, N and Hudson, C and Chien, LC and Henderson, CC and Cahill, PA (1997) NONLINEAR OPTICAL PROPERTIES OF ORGANIC MATERIALS X . In: Kuzyk, MG eds. `'Quadrupoled'' materials for second-order nonlinear optics
1996 Kowalczyk, TC and Singer, KD and Cahill, PA (1996) NONLINEAR FREQUENCY GENERATION AND CONVERSION . In: Gupta, MC and Kozlovsky, WJ and MacPherson, DC eds. Anomalous dispersion phase-matched second harmonic generation in poled polymer waveguides
1995 Kowalczyk, TC and Singer, KD and Cahill, PA (1995) NONLINEAR OPTICAL PROPERTIES OF ORGANIC MATERIALS VIII . In: Mohlmann, GR eds. Frequency doubling in poled polymers using anomalous dispersion phase-matching
1995 KOWALCZYK, TC and KOSC, TZ and SINGER, KD and BEUHLER, AJ and WARGOWSKI, DA and CAHILL, PA and SEAGER, CH and MEINHARDT, MB (1995) POLYMERS FOR SECOND-ORDER NONLINEAR OPTICS . In: Lindsay, GA and Singer, KD eds. GUEST-HOST CROSS-LINKED POLYIMIDES FOR INTEGRATED-OPTICS
2010 Liu Y.;Bolger B.;Cahill P.;McGuinness G. (2010) Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems Assembly of aligned polyvinyl alcohol-styrylpyridinium pendent group nanofibres for vascular tissue engineering applications
2008 Liu Y.;Cahill P.;McGuinness G. (2008) 8th World Biomaterials Congress 2008 Study on the structure of poly(vinyl alcohol) based hydrogels

Abstract

Year Publication
2016 Cahill, P;Fitzpatrick, E;Jay-Christian, H;Diana, S;Hakimjavadi, R;Redmond, E (2016) VASCULAR BIOLOGY III. HH RESPONSIVE CELLS CONTRIBUTE TO VSMC ACCUMULATION FOLLOWING VASCULAR INJURY. CLARE: ABST
2008 Vrana, NE;Cahill, P;McGuinness, G (2008) Behaviour of encapsulated vascular smooth muscle cells and endothelial cell. NEW ROCHELLE: ABST
2018 Molony, C;King, D;Julius, LAN;Fitzpatrick, E;Di Luca, M;Casey, G;Hakimjavadi, R;Burtenshaw, D;Healy, K;Canning, D;Keman, D;Llobera, A;Liu, WM;Morrow, D;Redmond, EM;Ducree, J;Cahill, PA (2018) INJURY-ACTIVATED VASCULAR CELLS SHARE A COMMON PHOTONIC FINGERPRINT WITH STEM CELL-DERIVED MYOGENIC PROGENY FOLLOWING INTERROGATION USING A LAB-ON-A-DISC (LOAD) PLATFORM. LONDON: ABST

Editorial

Year Publication
2012 Redmond E.;Cahill P. (2012) The NOX-ROS connection: Targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells. ED
2020 Burtenshaw D.;Cahill P.A. (2020) Natriuretic Peptides and the Regulation of Retinal Neovascularization. ED

Review Articles

Year Publication
2019 Mathew S.;Naik C.;Cahill P.;Bhonde R. (2019) Placental mesenchymal stromal cells as an alternative tool for therapeutic angiogenesis. REV
2016 Cahill P.;Redmond E. (2016) Vascular endothelium - Gatekeeper of vessel health. REV
2004 Cummins P.;Cotter E.;Cahill P. (2004) Hemodynamic regulation of metallopeptidases within the vasculature. REV
2001 Cahill P.;Redmond E.;Sitzmann J. (2001) Endothelial dysfunction in cirrhosis and portal hypertension. REV
2012 Cahill P.;Redmond E. (2012) Alcohol and cardiovascular disease-modulation of vascular cell function. REV
2001 Cahill, PA;Redmond, EM;Sitzmann, JV (2001) Endothelial dysfunction in cirrhosis and portal hypertension. REV

Other Publication

Year Publication
2000 Redmond EM, Sitzmann JV, Cahill PA. (2000) Potential mechanisms for cardiovascular protective effect of ethanol. Acta Pharmacol Sin.
2001 Cahill PA, Redmond EM, Sitzmann JV. (2001) Endothelial dysfunction in cirrhosis and portal hypertension. Pharmacol Ther.
2001 Cummins, PM;Coen, PM;Cahill, PA (2001) Regulation of endopeptidase EC 3.4.24.15 expression in vascular endothelial cells by mechanical forces.
2001 Theodorakis, NG;Wang, YN;Redmond, EM;Cahill, PA;Sitzmann, JV (2001) The role of nitric oxide synthase isoforms in the development of portal hypertension: Studies in gene-deficient mice.
2002 Birney, YA;Sweeney, C;Cappadona, C;Redmond, EM;Sitzmann, JV;Cahill, PA (2002) Pulse pressure-induced vascular smooth muscle cell apoptosis.
2002 Sweeney, NV;Birney, YA;Cummins, P;Cahill, PA (2002) Cyclic Strain Induces Pro-MMP2 release from bovine aortic endothelial cells via a Gi alpha protein-independent, MAP kinase-dependent pathway.
2002 Sweeney, N;Cummins, P;Cahill, PA (2002) Role of the SHC/MAP kinase pathway and Gi alpha proteins in cyclic strain induced increases in pro-MMP2 secretion.
2003 Walshe, TE;Connell, PP;O'Brien, CJ;Cahill, P (2003) Pulsatile flow regulates endothelial Nitric Oxide Synthase expression in co-cultured retinal endothelial & pericyte cells.
2003 Connolly, SB;Kieran, NE;Cahill, P;Sugrue, DD;Doran, P;Brady, HR (2003) Microarray analysis identifies pituitary tumor transforming gene I (PTTG1) and calvasculin as stretch-responsive vascular smooth muscle cell genes associated with atherosclerosis.
2003 Birney Y, Redmond EM, Sitzmann JV, Cahill PA (2003) Eicosanoids in cirrhosis and portal hypertension. Prostaglandins Other Lipid Mediat.
2003 Kim SI, Grum-Tokars V, Swanson TA, Cotter EJ, Cahill PA, Roberts JL, Cummins PM, Glucksman MJ (2003) Novel roles of neuropeptide processing enzymes: EC3.4.24.15 in the neurome. J Neurosci Res.
2003 Cotter, EJ;Cahill, PA;Cummins, PM (2003) Cyclic strain modulates activity of endopeptidases EC 3.4.24.15 and EC 3.4.24.16 in vascular endothelial cells.
2003 Coen, PM;Cummins, PM;Devery, R;Cahill, PA (2003) The effects of conjugated linoleic acid on nitric oxide synthase and cyclooxygenase expression and activity in vascular endothelial cells.
2003 Connell, PP;Wei, G;O'Brien, CJ;Cahill, P (2003) High glucose suppresses bovine retinal pericyte proliferation: Implications for retinopathy.
2004 Collins, NT;Colgan, OC;Ferguson-Welsby, G;Murphy, RP;Cummins, PM;Cahill, PA (2004) Cyclic strain regulates occludin and ZO-1 expression, phosphorylation, and localization in bovine aortic endothelial cells (BAEC).
2004 Cummins PM, Cotter EJ, Cahill PA (2004) Hemodynamic regulation of metallopeptidases within the vasculature. Protein Pept Lett.
2004 Sen, S;Bartlett, JS;Birney, Y;Cahill, P;O'Brien, T (2004) Cyclical mechanical stretch and AAV2 mediated gene transfer to cultured human vascular cells.
2004 Walshe, TE;Ferguson, G;Cahill, P;O'Brien, C (2004) Pulsatile flow regulates nitric oxide, prostacyclin & endothelin-1 levels in an endothelial cell pericyte co-culture.
2004 Connell, PP;O'Brien, CJ;Cahill, PA (2004) High Glucose Suppresses Pulsatile flow induced ppEnos protein expression and eNOS activity.
2005 Walshe, T;Cryan, L;O'Brien, C;Cahill, P (2005) Hedgehog signaling in the retinal vasculature.
2005 Cullen, JP;Jin, Y;Sweeney, NV;Sitzmann, JV;Cahill, PA;Redmond, EM (2005) Resveratrol downregulates CC chemokine receptor 2 binding and expression on THP-1 monocytes.
2005 Gao, W;Murphy, RP;Ferguson, G;Cahill, PA (2005) High glucose concentrations alter hypoxia-induced cell fate decisions in bovine aortic smooth muscle cells.
2005 Sweeney, NV;Cullen, JP;Cahill, PA;Redmond, EM (2005) Cyclic strain-induced MMP-9 activity in bovine aortic endothelial cells is mediated via a Notch/CBF-1 dependent pathway.
2005 Fitzpatrick, PA;Cotter, EJ;Birney, YA;Glucksman, MJ;Cahill, PA;Cummins, PM;Franklin, R (2005) Expression of Thermolysin-Like zinc metalloendopeptidases in vascular endothelial cells is regulated by shear stress and reactive oxygen species.
2005 Collins, NT;Cummins, PM;Colgan, OC;Birney, YA;Ferguson, G;Murphy, RP;Cahill, PA (2005) Cyclic strain regulates occludin and Z0-1 expression, phosphorylation and localisation in bovine aortic endothelial cells.
2005 Cullen, JP;Sweeney, NV;Cahill, PA;Redmond, EM (2005) C-reactive protein-mediated inhibition of endothelial cell PAI-1 production is prevented by ethanol and resveratrol.
2005 Cotter, EJ;Fitzpatrick, PA;Birney, Y;Wu, TJ;Glucksman, MJ;Cahill, PA;Cummins, PM (2005) Cyclic strain induces changes in EP24.15 subcellular localization, and peptide cleavage; Possible implications for endothelial cell fate decisions.
2006 Cullen, JP;Jin, Y;Von Offenberg, N;Cahill, PA;Redmond, EM (2006) Inhibition of chemokine receptor CCR2 mRNA expression and binding by resveratrol; Role of nitric oxide and mitogen activated protein kinase.
2006 Sweeney, C. H.;Cahill, P. A.;Bresnihan, B.;FitzGerald, O.;Fearon, U.;Veale, D. J. (2006) A role for the survivin and notch signalling pathways in blood vessel maturation and synovial hyperplasia in rheumatoid arthritis.
2006 Tobin, NP;Cummins, PM;Henehan, G;Cahill, PA (2006) Helicobacter pylori outer membrane protein effects vascular endothelial cell fate decisions in vitro.
2006 Fitzpatrick, PA;Killeen, MT;Birney, YA;Glucksman, MJ;Cahill, PA;Cummins, PM (2006) Shear stress regulation of NEP is mediated via reactive oxygen species in endothelial cells.
2006 Colgan, OC;Cummins, PM;Collins, NT;Birney, YA;Ferguson, G;Cahill, PA (2006) Co-culture of bovine brain microvascular endothelial cells (BBMvEC) and C6 glioma decreases endothelial permeability and increases tight junction formation.
2006 Cullen, JP;Cahill, PA;Redmond, EM (2006) Cyclic strain regulates the plasminogen activator system in human umbilical venous endothelial cells.
2006 Gao, W;Murphy, RP;Ferguson, G;Cahill, PA (2006) Hyperglycaemia alters hypoxia-induced cell fate decisions in bovine aortic endothelial cells.
2006 Colgan, OC;Collins, NT;Birney, YA;Ferguson, G;Cahill, PA;Cummins, PM (2006) Shear stress regulates microvascular endothelial occludin and ZO-1 and increases tight junction formation.
2007 Kennedy, A.;Sweeney, C.;Walshe, T.;Cahill, P. A.;Bresnihan, B.;Fitzgerald, O.;Fearon, U.;Veale, D. J. (2007) Regulation of VEGF and angiopoietins in inflammatory arthritis.
2007 Morrow, David;Cullen, John P.;Cahill, Paul A.;Redmond, Eileen M. (2007) Ethanol stimulates endothelial cell angiogenic activity via a Notch/CBF-1/RBP-Jk-dependent pathway.
2007 Killeen, Maria T.;Murphy, Ronan P.;Cahill, Paul A.;Cummins, Philip M. (2007) Cyclic strain of vascular endothelial cells reduces vascular smooth muscle cell proliferation, possibly via an MMP-2-dependent mechanism.
2007 Cummins, P.M.;Sweeney, N.V.O.;Killeen, M.T.;Birney, Y.A.;Redmond, E.M.;Cahill, P.A. (2007) Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: A force to be reckoned with. Link
2007 Cummins PM, von Offenberg Sweeney N, Killeen MT, Birney YA, Redmond EM, Cahill PA (2007) Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: a force to be reckoned with. Am J Physiol Heart Circ Physiol.
2007 Morrow, David;Cullen, John P.;Cahill, Paul A.;Redmond, Eileen M. (2007) Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: Role in angiogenesis.
2007 Colombo, Alberto;Cahill, Paul;Lally, Caitriona (2007) The frequency of cyclic stretch determines the proliferative and apoptotic capacity of vascular smooth muscle cells in vitro.
2008 Morrow, David;Cullen, John P.;Cahill, Paul A.;Redmond, Eileen M. (2008) Stimulation of notch signaling in endothelial cells by ethanol: Role in angiogenesis.
2008 Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O'Brien C, Walls D, Redmond EM, Cahill PA (2008) Notch and vascular smooth muscle cell phenotype. Circ Res.
2009 Morrow, David;Cullen, John P.;Liu, Weimin;Cahill, Paul A.;Redmond, Eileen M. (2009) A VEGF-Notch Signaling Pathway Mediates the Effect of Ethanol on Endothelial Angiogenic Activity.
2009 Morrow, David;Liu, Weimin;Cullen, John P.;Cahill, Paul A.;Redmond, Eileen M. (2009) Regulation of Notch Signaling in Vascular Smooth Muscle Cells by Alcohol.
2011 Morrow, D.;Cullen, J.;Cahill, P.;Redmond, E. (2011) ALCOHOL INHIBITS NOTCH SIGNALING IN VASCULAR SMOOTH MUSCLE CELLS AT THE LEVEL OF gamma-SECRETASE.
2013 Hatch, E.;Morrow, D.;Cahill, P. A.;Redmond, E. M. (2013) ALCOHOL REGULATION OF NOTCH SIGNALING IN VASCULAR CELLS.
2014 Morrow, D.;Hatch, E.;Hamm, K.;Cahill, P. A.;Redmond, E. M. (2014) ETHANOL INHIBITS HEDGEHOG SIGNALING IN CULTURED VASCULAR SMOOTH MUSCLE CELLS AND IN LIGATION-INJURED VESSELS IN VIVO.
2016 Alshamrani, Maryam;Cahill, Paul A. (2016) Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease.
2018 Di Luca, Mariana;Fitzpatrick, Emma;Liu, Weimin;Morrow, David;Redmond, Eileen M.;Cahill, Paul A. (2018) CHARACTERISATION OF RESIDENT MULTIPOTENT VASCULAR STEM CELLS (MVSCS) FROM SUSCEPTIBLE AND NON-SUSCEPTIBLE ARTERIOSCLEROTIC REGIONS OF THE MOUSE AORTA.
2018 Burtenshaw, Denise;Fitzpatrick, Emma;Liu, Weimin;Morrow, David;Redmond, Eileen M.;Cahill, Paul A. (2018) RESIDENT S100 beta/SCA1(+) MULTIPOTENT VASCULAR STEM CELLS UNDERGO MYOGENIC AND VASCULOGENIC DIFFERENTIATION IN VITRO.
2018 Olayinka, Abidemi;Corcoran, Eoin;O'Connor, Brendan;Cahill, Paul A. (2018) THE ROLE OF N-GLYCOSYLATION OF THE NOTCH1 RECEPTOR IN JAGGED1-STIMULATED MYOGENIC DIFFERENTIATION IN VITRO.
2018 Fitzpatrick, Emma;Liu, Weimin;Alshamrani, Maryam;Helt, Jay-Christian;Hakimjavadi, Roya;Harman, Susan;Olayinka, Abidemi;Burtenshaw, Denise;Corcoran, Eoin;Di Luca, Mariana;Lally, Catriona;Redmond, Eileen M.;Cahill, Paul A. (2018) HEDGEHOG RESPONSIVE STEM CELL ANTIGEN-1/S100 beta RESIDENT VASCULAR STEM CELLS CONTRIBUTE TO NEOINTIMAL FORMATION.
2018 Bashmail, Roa;Mckenna, Niamh;O'Shea, Ciaran;Hakimjavadi, Roya;Molony, Claire;Kozlowska, Dorota;Cahill, Paul A. (2018) Generation of gamma-secretase Inhibitor-loaded PLGA-Fe3O4- Magnetic Nanoparticles.
2018 Kakimjavadi, Roya;Burtenshaw, Denise;Fitzpatrick, Emma;Di Luca, Mariana;Corcoran, Eoin;Casey, Gillian;Redmond, Eileen M.;Cahill, Paul A. (2018) STEM-CELL DERIVED MYOGENIC PROGENY ENRICH FOR VASCULAR SMOOTH MUSCLE CELL EPIGENETIC MARKS AT THE MYOSIN HEAVY CHAIN 11 PROMOTER IN VITRO.
2018 Corcoran, Eoin;Olayinka, Abidemi;O'Connor, Brendan;Cahill, Paul A. (2018) The Role of N-glycosylation in the Myogenic Differentiation of Stem Cells to Vascular Smooth Muscle Cells.
2019 Liu, W.;Wahl, A.;Cahill, P. A.;Redmond, E. M. (2019) ATHEROPROTECTIVE EFFECTS OF ALCOHOL CONSUMPTION; VASCULAR STEM CELLS AS A NOVEL TARGET POPULATION.
Certain data included herein are derived from the © Web of Science (2021) of Clarivate. All rights reserved.

Professional Associations

Association Function From / To
British Pharmacological Society (BPS) Member 01/01/1996 - 30/12/1899
European Atherosclerosis Association (EAS) Member 01/06/2016 - 31/05/2017
American Heart Association (AHA) member 01/01/1993 - 30/12/1899
North American Vascular Biology Organization (NAVBO) Member 01/01/1994 - 30/12/1899
Irish Association of Pharmacologists (IAP) President elect 2000 President 2001 01/01/1987 - 30/12/1899

Honors and Awards

Date Title Awarding Body
01/10/1986 Irish Department of Education
01/03/1987 Health Research Board of Ireland
01/11/1999 Wellcome Trust/New Blood Fellowship
01/06/1987 Health Research Board of Ireland
01/11/1996 American Association for the Study of Liver Diseases
01/09/2000 Scientia Europea Attendee
01/11/2001 President Irish Association of Pharmacologists
01/10/1987 Health Research Board of Ireland
01/07/1989 Proctor and Gamble
01/01/1992 National Institutes of Health
01/06/1994 Gordon Research Conference
01/11/1993 American Association for the Study of Liver Diseases
01/06/1997 Chinese Medical Association

Committees

Committee Function From / To
Academic Council 01/04/2018 -
Animal Welfare Body 01/01/2017 -
BRAG Committee 01/06/2014 - 31/12/2016
Health Research BoardHRB- Interdisciplinary panel 01/06/2001 - 01/06/2001
DCU Life Sciences and Health Strategic Committee Member, 2001 01/03/2001 - 01/10/2001
Health Research Board, Project Grant Committee memeber Cell and Molecular 01/01/2001 - 01/01/2004
Health Research Board, Progect Grant Committee member Cardiovascular and Renal 01/01/2001 - 01/01/2004
Health Research Board, HRB review panels (North-South Co-operation) 01/04/2000 - 01/04/2000
Enterprise Ireland, Basic Research Grants, Life Sciences Panel 01/01/2000 - 01/01/2003
DCU Research Committee member 01/01/2000 - 01/10/2000
DCU School of Biotechnology, Research Convenor 01/11/1999 - 01/10/2000
Georgetown University, Task Force committee member; Committee on Purchasing 01/01/1997 - 01/06/1997
Georgetown University, Task Force committee member; Committee on Compensation for Teaching 01/01/1997 - 01/06/1997
Georgetown University Medical Center Research Committee member 01/01/1995 - 01/01/1998

Employment

Employer Position From / To
Johns Hopkins University, Baltimore MD Instructor - Research 01/07/1992 - 01/06/1995
Dublin City University Associate Professor - Permanent 01/03/2001 - 30/09/2015
Dublin City University Senior Lecturer - Permanent 02/01/2000 - 01/03/2000
Georgetown University, Washington DC Associate Professor - Research 01/07/1997 - 01/06/1999
Georgetown University, Washington DC Assistant Professor - Research 01/07/1995 - 01/06/1997
New York Medical College, Valhalla Postdoctoral fellow 01/07/1990 - 01/05/1991
University of Rochester, Rochester NY Full Professor - Research 01/07/1999 - 30/11/1999
Dublin City University Full Professor - Permanent 01/10/2015 -
The University of Tennessee, Memphis, TN Postdoctoral Fellow 01/07/1991 - 01/06/1992

Education

Start date Institution Qualification Subject
University College Dublin PhD
University College Dublin BSc

Other Activities

Description
Director of Surgical Research, University of Rochester - champion of research programme for surgical residents at the University
Invited on Editorial Board Computational Biology
Director of Surgical Research, Georgetown University - champion of research programme for surgical residents at the University
Chairperson of the Genetic and Cell Biology programme fulfilling all the duties of this post for GCB-1, -2,-3 and 4.
Invited on Editorial Board for Angiogenesis
President, Irish Association of Pharmacologists- All Ireland Irish Society of Pharmacologists - organised annual meeting of Society held in Mount Clare Hotel, Dublin

Enterprise Engagement

Year Engagement Type Client Description
2001 Consultancy Science Foundation Ireland (SFI) Principal Research Officer and team member working with Dr Bill Harris, Director of SFI on FDI projects including Project Olympiad and Molecular Medicine initiatives
2002 Equipment use/Access to Infrastructure Elan Pharmaceuticals Ltd Enterprise Ireland Innovation Partnership Programme
2002 Consultancy Medtronic Ave Consultant for company looking at vulnerable plaque and methods of detection
2003 Equipment use/Access to Infrastructure Bayer Healthcare AG Equipment Access - Doppler Flow Probes
2013 Continuous Professional Development/Training Solvotrin Innovations Ltd Irish Research Council (IRC) Enterprise Partnership Programme

Media

Title Year Type Authors
Novel approach to fighting disease 2002 Newspaper article (Print) Dick Ahlstrom
Five get £1.2m for medical research 1999 Newspaper article (Print) Dick Ahlstrom

Research Interests

Cardiovascular diseases remain a major cause of mortality worldwide.  Vascular biology is an exciting and rapidly advancing area of biomedical research that has led to significant insights into the treatment not only of vascular diseases such as atherosclerosis, arteriosclerosis, in-stent restenosis and hypertension, but also diabetes and tumor development.  

Arteriosclerosis is an important age-dependent disease that encompasses atherosclerosis, in-stent restenosis (ISR), pulmonary hypertension, autologous bypass grafting and transplant arteriosclerosis. Endothelial dysfunction and the proliferation of vascular smooth muscle cell (vSMC)-like cells is a critical event in the pathology of vascular disease leading to intimal-medial thickening (IMT), lipid retention and vessel remodelling. An important aspect in guiding clinical decision-making is the detection of biomarkers of early cardiovascular risk. Crucially, relevant biomarkers need to be good indicators of injury which change in their circulating concentrations or structure, signalling functional disturbances.

Extracellular vesicles (EVs) are small membrane-bound vesicles secreted by cells that contain numerous bioactive molecules and act as a means of intercellular communication between different cell populations to maintain tissue homeostasis, gene regulation in recipient cells and the adaptive response to stress.


MAJOR RESEARCH AREAS:
  • Development of a pipeline for the generation of novel, multitargeted, next generation pleiotropic cell therapy biologics derived from allogeneic immortalized human bone-marrow derived MSCs
  • Point-of-Care Diagnostics (POCD) for subclinical arteriosclerotic disease using exosomal profiling
  • Endothelial derived extracellular vesicles (EVs) following endothelial dysfunction - dictating the phenotype of resident vascular stem cells, smooth muscle cells and adventitial cells during adaptive lesion formation and progression of arteriosclerotic disease.
  • Gene regulatory networks (Notch and Hedgehog) that control resident vascular stem cell fate - myogenic, osteogenic, adipogenic, vasculogenic and myeloid differentiation
  • Mechanical stimuli (shear stress, cyclic strain and pressure) and developmental gene regulatory network control of vascular smooth muscle and endothelial cell phenotype and fate.
  • Lineage tracing analysis and epigenetic profiling of resident vascular stem cells during arteriosclerotic disease progression
  • Single cell auto-fluorescence photonic emissions and vibrational spectroscopy to discriminate vascular cell phenotypes using supervised machine learning
  • Magnetic nanoparticles as drug-delivery platform for vascular stents
  • Vascular tissue engineering

Research Projects

Title Role Description Start date End date
Resident Vascular Stem Cells and Diabetes Supervisor 05/11/2018 30/09/2022
Vascular protective Effects of Alcohol - The Role of Notch Co-I 01/09/2017 31/07/2022
N-Glycans and Notch 1 control of resident vascular stem cell transition to smooth muscle Supervisor 01/10/2016 30/09/2020
Alcohol Regulation of Resident Vascular Stem Cells Co Investigator 01/01/2015 31/08/2017
Development of second generation therapeutics for drug eluting stents using magnetic nanoparticles Supervisor 01/10/2014 30/09/2018
The Embryological Origin of Resident Vascular Stem Cells - Implications for Vascular Disease. Supervisor 01/01/2014 30/09/2018
Targeting Vascular Stem Cells with Magnetic Nanoparticles loaded with Notch Inhibitors Supervisor 01/10/2013 30/09/2018
Targeting Vascular Stents with Drug Loaded Magnetic Nanoparticles - Development of 2nd Generation Drug-Eluting Stents Mentor 01/10/2013 30/09/2015
Development of second generation therapeutics for drug eluting stents using magnetic nanoparticles Supervisor 01/01/2013 30/09/2017
Notch signalling and Vascular Remodelling - a Novel target for Therapeutic Intervention Principal Investigator 01/04/2012 31/03/2017
GSK-3beta and MSC differentiation Co Investigator 01/10/2010 30/09/2013

Contract Researchers

Researcher Name Project Funding Body
Dr Michael Kitching SFI COVID-19 Rapid Award
Denise Burtenshaw Endothelial Control of Stem Cell Fate
Dr Roya Hakimjavadi Hedgehog Control of Resident Vascular Stem Cells
Dr Imen Gdara EvPRO

Current Postgraduate Students

Student Name Degree Supervision
O Maolmhuaidh ,Fionn PhD Supervisor
Harman ,Susan PhD-track Supervisor
Alanazi ,Muhayla MSc Supervisor
Corcoran ,Eoin PhD Supervisor
Burtenshaw ,Denise PhD Supervisor
Gusti ,Yusof Shukri Y PhD Supervisor
Buchanan ,Ciara PhD-track Supervisor

External Collaborators

Type Name Company Role
External Professor Colm O' Brien Institute of Opthamology, Mater Hospital, Dublin Academic
External Dr Bart van Dijk Lonza Pharma Industry
External Dr Birgit Nelsen-Salz Lonza Pharma Industry
External Prof James McLoughlin University of Ulster Academic
External Prof Bernd Giebel University of Essen Academic
External Prof Lorraine O'Driscoll Trinity Collge Dublin Academic
External Prof Catriona Lally Trinity Collge Dublin Academic
External Dr. Eileen M. Redmond, Associate Professor, Department of Surgery, University of Rochester, Ro University of Rochester Academic
External Dr Sanjay Sinha Cambridge University Academic

Modules Coordinated

Term Title Subject
2022 Literature Review & Experimental Design BE487
2022 Cell Structure and Function BE230
2022 Cell Biol.,Recombinant DNA Cloning & Bioinf. BE357
2022 Research Project BE492
2022 Research Project BE488
2022 Biopharmaceutical Chemistry BE333
2022 Description of 2021_BE494 BE494
2022 Literature Review & Experimental Design BE489
2022 Current Topics in Genetics & Cell Biology BE417
2022 Environmental Toxicology BE436
2022 Analytical Science Literature Survey BE493