Linda Holland

Assist. Prof

Contact Details

T:Ext. 5708


T:Ext. 5708
Profile Photo

I am currently an assistant professor of microbiology and teach across several degree programmes and years. My research is focused on understanding the interactions that occur between fungal and bacterial pathogens during biofilm infections. I am also interested in how mixed infections can alter antimicrobial tolerance during biofilm infections. 

Peer Reviewed Journal

Year Publication
2014 Holland LM;Schröder MS;Turner SA;Taff H;Andes D;Grózer Z;Gácser A;Ames L;Haynes K;Higgins DG;Butler G; (2014) 'Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans'. PLoS Pathogens, 10 (9). [DOI]
2014 Maguire SL;Wang C;Holland LM;Brunel F;Neuvéglise C;Nicaud JM;Zavrel M;White TC;Wolfe KH;Butler G; (2014) 'Zinc finger transcription factors displaced SREBP proteins as the major Sterol regulators during Saccharomycotina evolution'. PLoS Genetics, 10 (1). [DOI]
2013 Connolly LA;Riccombeni A;Grózer Z;Holland LM;Lynch DB;Andes DR;Gácser A;Butler G; (2013) 'The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis'. Molecular Microbiology, 90 (1). [DOI]
2013 Pammi M;Holland L;Butler G;Gacser A;Bliss JM; (2013) 'Candida parapsilosis is a significant neonatal pathogen: a systematic review and meta-analysis'. Pediatric Infectious Disease, 32 (5). [DOI]
2011 Holland LM;Conlon B;O'Gara JP; (2011) 'Mutation of tagO reveals an essential role for wall teichoic acids in Staphylococcus epidermidis biofilm development'. Microbiology (Reading, England), 157 (Pt 2). [DOI]
2011 Sai S;Holland LM;McGee CF;Lynch DB;Butler G; (2011) 'Evolution of mating within the Candida parapsilosis species group'. Eukaryotic Cell, 10 (4). [DOI]
2010 Oduwole KO;Glynn AA;Molony DC;Murray D;Rowe S;Holland LM;McCormack DJ;O'Gara JP; (2010) 'Anti-biofilm activity of sub-inhibitory povidone-iodine concentrations against Staphylococcus epidermidis and Staphylococcus aureus'. Journal Of Orthopaedic Research : Official Publication Of The Orthopaedic Research Society, 28 (9). [DOI]
2008 Holland LM;O'Donnell ST;Ryjenkov DA;Gomelsky L;Slater SR;Fey PD;Gomelsky M;O'Gara JP; (2008) 'A staphylococcal GGDEF domain protein regulates biofilm formation independently of cyclic dimeric GMP'. Journal of Bacteriology, 190 (15). [DOI]
2021 Fitzgerald, S.;Holland, L.;Morrin, A. (2021) 'An Investigation of Stability and Species and Strain-Level Specificity in Bacterial Volatilomes'. Frontiers in Microbiology, 12 . [Link] [DOI]
2021 O'Flynn D;Lawler J;Yusuf A;Parle-McDermott A;Harold D;Mc Cloughlin T;Holland L;Regan F;White B; (2021) 'A review of pharmaceutical occurrence and pathways in the aquatic environment in the context of a changing climate and the COVID-19 pandemic'. Analytical Methods, 13 (5). [DOI]
2021 Yusuf, A;O'Flynn, D;White, B;Holland, L;Parle-McDermott, A;Lawler, J;McCloughlin, T;Harold, D;Huerta, B;Regan, F (2021) 'Monitoring of emerging contaminants of concern in the aquatic environment: a review of studies showing the application of effect-based measures'. Analytical methods : advancing methods and applications, . [DOI]
2020 Brennan B;Briciu-Burghina C;Hickey S;Abadie T;Al Ma Awali SM;Delaure Y;Durkan J;Holland L;Quilty B;Tajparast M;Pulit C;Fitzsimons L;Nolan K;Regan F;Lawler J; (2020) 'Pilot Scale Study: First Demonstration of Hydrophobic Membranes for the Removal of Ammonia Molecules from Rendering Condensate Wastewater'. International Journal of Molecular Sciences, 21 (11). [DOI]
2020 Fitzgerald, S;Duffy, E;Holland, L;Morrin, A (2020) 'Multi-strain volatile profiling of pathogenic and commensal cutaneous bacteria'. Scientific Reports, 10 . [DOI]
2018 Iracane, E.;Donovan, P.D.;Ola, M.;Butler, G.;Holland, L.M. (2018) 'Identification of an exceptionally long intron in the HAC1 gene of Candida parapsilosis'. Msphere, 3 . [Link] [DOI]
2018 Donovan P.;Holland L.;Lombardi L.;Coughlan A.;Higgins D.;Wolfe K.;Butler G. (2018) 'TPP riboswitch-dependent regulation of an ancient thiamin transporter in Candida'. PLoS Genetics, 14 (5). [DOI]
2016 Luke M Noble, Linda M Holland, Alisha J McLauchlan, Alex Andrianopoulos (2016) 'A Plastic Vegetative Growth Threshold Governs Reproductive Capacity in Aspergillus nidulans'. . [DOI]
Certain data included herein are derived from the © Web of Science (2022) of Clarivate. All rights reserved.


Employer Position From / To
Dublin City University Lecturer in Microbiology 05/09/2016 - 11/04/2018
University College Dublin Post-doctoral Research Fellow 02/03/2009 - 27/12/2013
University of Melbourne ELEVATE/Marie-Cure Fellow 02/01/2014 - 02/09/2016


Start date Institution Qualification Subject
University College Dublin PhD
University College Cork BSc Microbiology


Journal Role
Journal of Applied Microbiology Reviewer
Eukaryotic Cell Reviewer
PLoS Genetics Reviewer
Microbial Pathogenesis Reviewer

Research Interests

My research is focused on understanding the interactions that occur between fungal and bacterial pathogens during biofilm formation. I am also interested in studying the effects of polymicrobial interactions on antimicrobial tolerance of bacteria and fungal pathogens. 

Research Projects

Title Role Description Start date End date
ZOI experiment training and supervision of ATD Emolda Staff DCU PI 01/03/2018 31/03/2018
Research agreement between DCU and ATD Emolda 2020 DCU PI 29/01/2020 31/12/2020
Research Agreement between DCU and ATD Emolda 2019 DCU PI 28/01/2019 31/12/2019
Research agreement between DCU and ATD Emolda DCU PI 15/12/2020 31/12/2021
Cross-kingdom interactions and bio-communication DCU PI 02/09/2019 02/03/2022
Identification of a fungal factor that inhibits Staphylococcus aureus biofilm formation. DCU PI 01/11/2021 31/08/2022

Current Postgraduate Students

Student Name Degree Supervision
Fitzgerald ,Shane PhD Supervisor
Furlong ,Ciara PhD Supervisor

Internal Collaborators

Type Name Company Role
Internal Dr Aoife Morrin Dublin City University Academic
Internal Prof Fiona Regan Dublin City University Academic

External Collaborators

Type Name Company Role
External Prof James O'Gara NUIG Academic
External Prof Eoghan O'Neill RCSI Academic

Teaching Interests

I teach a variety of modules focused on microbial genetics, wastewater treatment, food/water microbiology and environmental microbiology. I am particularly interested in using problem based learning to encourage engagement of students in my lecture material. I am also keen to introduce problem based learning to my undergraduate laboratory modules. I enjoy teaching using hybrid methods - pre-recorded material and face-to-face interactive tutorials. 

Modules Coordinated

Term Title Subject
2022 Microbiology and Genetics II BE233
2022 Industrial Bioprocessing BE401
2022 Bioanalysis BE311
2022 Research Project BE488
2022 Enviromental Biotechnology Laboratories BE256
2022 Environmental Biotechnology BE332
2022 Literature Review & Experimental Design BE489
2022 Literature Review & Experimental Design BE487
2020 Molecular Diagnostics BE529AU
2022 BE486
2022 BE586
2022 Description of 2021_BE494 BE494
2022 Research Project BE492
2022 Pollution & Biosphere BE208