David B. MacManus

Dr.

Contact Details


SA313
T:Ext. 8768

E:David.MacManus@dcu.ie

Assistant Professor of Biomedical Engineering



Profile Photo
Dr David MacManus graduated with a degree in Mechanical and Manufacturing Engineering from Trinity College Dublin in 2013. Following this, David began his PhD studies at University College Dublin where his research focused on the biomechanics of traumatic brain injury. His PhD thesis was awarded the Broberg Medal for Best PhD Thesis in Mechanics at University College Dublin in 2017. In 2018, David was awarded a Science Foundation Ireland Industry Fellowship to investigate the biological mechanisms underlying insulin-induced injection-site lipohypertrophy. David has since joined the School of Mechanical & Manufacturing Engineering at Dublin City University as an Assistant Professor of Biomedical Engineering. David’s research focuses on the biomechanics of traumatic brain injury, and in particular, on mechanical characterisation of brain tissue, and development of novel helmet designs.

Peer Reviewed Journal

Year Publication
2020 Pierrat, B;Carroll, L;Merle, F;MacManus, DB;Gaul, R;Lally, C;Gilchrist, MD;Annaidh, AN (2020) 'Mechanical Characterization and Modeling of the Porcine Cerebral Meninges'. Frontiers In Bioengineering And Biotechnology, 8 . [DOI]
2020 Menichetti A.;MacManus D.B.;Gilchrist M.D.;Depreitere B.;Vander Sloten J.;Famaey N. (2020) 'Regional characterization of the dynamic mechanical properties of human brain tissue by microindentation'. International Journal of Engineering Science, 155 . [DOI]
2016 MacManus, DB;Pierrat, B;Murphy, JG;Gilchrist, MD (2016) 'Mechanical characterization of the P56 mouse brain under large-deformation dynamic indentation'. Scientific Reports, 6 . [DOI]
2017 MacManus, DB;Gilchrist, MD;Murphy, JG (2017) 'An empirical measure of nonlinear strain for soft tissue indentation'. Royal Society Open Science, 4 . [DOI]
2017 MacManus, DB;Pierrat, B;Murphy, JG;Gilchrist, MD (2017) 'A viscoelastic analysis of the P56 mouse brain under large-deformation dynamic indentation'. Acta Biomaterialia, 48 :309-318. [DOI]
2017 MacManus, DB;Pierrat, B;Murphy, JG;Gilchrist, MD (2017) 'Region and species dependent mechanical properties of adolescent and young adult brain tissue'. Scientific Reports, 7 . [DOI]
2017 MacManus, DB;Pierrat, B;Murphy, JG;Gilchrist, MD (2017) 'Protection of cortex by overlying meninges tissue during dynamic indentation of the adolescent brain'. Acta Biomaterialia, 57 :384-394. [DOI]
2018 MacManus, DB;Pierrat, B;Murphy, JG;Gilchrist, MD (2018) 'Region and species dependent mechanical properties of adolescent and young adult brain tissue (vol 7, 2017)'. Scientific Reports, 8 . [DOI]
2018 Pierrat, B;MacManus, DB;Murphy, JG;Gilchrist, MD (2018) 'Indentation of heterogeneous soft tissue: Local constitutive parameter mapping using an inverse method and an automated rig'. Journal of the Mechanical Behavior of Biomedical Materials, 78 :515-528. [DOI]
2020 MacManus, D.B.;Menichetti, A.;Depreitere, B.;Famaey, N.;Vander Sloten, J.;Gilchrist, M. (2020) 'Towards animal surrogates for characterising large strain dynamic mechanical properties of human brain tissue'. Brain Multiphysics, 1 . [Link] [DOI]
2019 MacManus D.;Maillet M.;O'Gorman S.;Pierrat B.;Murphy J.;Gilchrist M. (2019) 'Sex- and age-specific mechanical properties of liver tissue under dynamic loading conditions'. Journal of the Mechanical Behavior of Biomedical Materials, 99 :240-246. [DOI]
2018 MacManus D.;Murphy J.;Gilchrist M. (2018) 'Mechanical characterisation of brain tissue up to 35% strain at 1, 10, and 100/s using a custom-built micro-indentation apparatus'. Journal of the Mechanical Behavior of Biomedical Materials, 87 :256-266. [DOI]
2017 Gilchrist, MD;MacManus, D;Murphy, JG;Pierrat, B (2017) 'A new formulation of slight compressibility for arterial tissue and its Finite Element implementation'. Computer methods in biomechanics and biomedical engineering, 20 :403-414. [DOI]
2016 Pierrat B.;Murphy J.;MacManus D.;Gilchrist M. (2016) 'Finite element implementation of a new model of slight compressibility for transversely isotropic materials'. Computer methods in biomechanics and biomedical engineering, 19 (7):745-758. [DOI]
2016 Gilchrist M.;MacManus D.;Murphy J.;Pierrat B. (2016) 'A new formulation of slight compressibility for arterial tissue and its Finite Element implementation'. Computer methods in biomechanics and biomedical engineering, :1-12. [DOI]
2015 MacManus D.;Pierrat B.;Murphy J.;Gilchrist M. (2015) 'Dynamic mechanical properties of murine brain tissue using micro-indentation'. Journal of Biomechanics, 48 (12):3213-3218. [DOI]
Certain data included herein are derived from the © Web of Science (2022) of Clarivate. All rights reserved.

Research Interests

Traumatic brain injury; biomechanics; mechanical characterisation of biological tissues; indentation; lipohypertrophy; medical device design; finite element modelling.

Modules Coordinated

Term Title Subject
2022 Product Development & Regulatory Compliance MM371
2022 Rehabilitation Engineering MM498
2022 Adv Eng Materials & Manufacturing Processes MM409
2022 Biomechanics of Tissue Engineering MM517