Ruairí Brannigan


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Ruairí completed his degree in Chemical and Pharmaceutical studies at Dublin City University (2011), before undertaking an industrially sponsored PhD in Polymer Chemistry at the University of Warwick, entitled ‘Design of novel monomers for applications in hydrolytically degradable thermoplastic elastomers’. After completing his PhD in 2015, Ruairí undertook a short Research Assistant position with Critical Pharmaceuticals Ltd investigating the synthesis of degradable particles from supercritical carbon dioxide for sustained release applications, before beginning a Leverhulme Trust funded Postdoctoral position at the University of Reading. While at the University of Reading, Ruairí worked on the synthesis and design of novel mucoadhesive materials, and developed a novel family of mucoadhesive polymer formulations. In 2017, Ruairí was awarded a Marie Skłodowska-Curie Actions individual fellowship and was featured as one of the 30 promising researchers in Europe after attaining the highest grading for the Chemistry strand. Ruairí conducted his MSCA fellowship in the Royal College of Surgeons in Ireland (RCSI) developing next generation biomaterials through the synthesis of polyester-peptide hybrid materials. Upon completion of his MSCA fellowship, Ruairí held a Senior Postdoctoral position at RCSI and played a central role in the attainment of an Enterprise Ireland Commercialisation Fund (StarMat).  

In 2021, Ruairí commenced a HCI funded Assistant Professor position in DCU in Materials Chemistry. Ruairí is attracted to the challenges faced in bridging the gap between pragmatic monomer design, synthetic polymer chemistry and materials science in the control of bulk properties of advanced materials for biomedical, agricultural and packaging industries. His current research strands focus on (i) sustainable monomer feedstocks for the synthesis of biodegradable and bio-absorbable polymers and (ii) bioadhesive elastomers for post-operative wound healing. 

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Conference Publication

Year Publication
2012 Thornton P.; Brannigan R.; Podporska J.; Quilty B.; Heise A. (2012) Journal of Materials Science: Materials in Medicine The generation of hydrophilic polypeptide-siloxane conjugates via n-carboxyanhydride polymerisation [DOI]

Peer Reviewed Journal

Year Publication
2023 Maria C. Arno; Joshua D. Simpson; Lewis D. Blackman; Ruairí P. Brannigan; Kristofer J. Thurecht; Andrew P. Dove (2023) 'Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platform'. Biomaterials Science, . [Link] [DOI]
2023 Smiljana Stefanovic; Katie McCormick; Sarinj Fattah; Ruairi P Brannigan; Sally-Ann Cryan; Andreas Heise (2023) 'Star-shaped poly(l-lysine) with polyester bis-MPA dendritic core as potential degradable nano vectors for gene delivery'. Polymer Chemistry, . [Link] [DOI]
2022 A. Chanteli; M. Ó Conaire; R. P. Brannigan; A. Heise; P. M. Weaver; I. Manolakis (2022) 'Cleavable epoxy networks using azomethine-bearing amine hardeners'. REACTIVE & FUNCTIONAL POLYMERS, . [Link] [DOI]
2022 Nicola Judge; Dražen Pavlović,; Evelin Moldenhauer; Paul Clarke; Ruairi Brannigan; Andreas Heise (2022) 'Influence of the block copolypeptide surfactant structure on the size of polypeptide nanoparticles obtained by mini emulsion polymerisation'. Polymer Chemistry, . [Link] [DOI]
2020 Tonglairoum, P; Brannigan, RP; Opanasopit, P; Khutoryanskiy, VV (2020) 'Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery'. Journal of materials chemistry. B, 4 (40). [DOI]
2020 O'Brien, S; Brannigan, RP; Ibanez, R; Wu, B; O'Dwyer, J; O'Brien, FJ; Cryan, SA; Heise, A (2020) 'Biocompatible polypeptide-based interpenetrating network (IPN) hydrogels with enhanced mechanical properties'. Journal of materials chemistry. B, 8 (34). [DOI]
2020 Brannigan, R.P.; Heise, A. (2020) 'Synthesis of mechanically robust renewable poly(ester-amide)s through co-polymerisation of unsaturated polyesters and synthetic polypeptides'. European Polymer Journal, 123 . [Link] [DOI]
2019 Brannigan, RP; Khutoryanskiy, VV (2019) 'Progress and Current Trends in the Synthesis of Novel Polymers with Enhanced Mucoadhesive Properties'. Macromolecular Bioscience, 19 (10). [DOI]
2019 Brannigan, R.P.; Walder, A.; Dove, A.P. (2019) 'Application of functional diols derived from pentaerythritol as chain extenders in the synthesis of novel thermoplastic polyester-urethane elastomers'. Polymer Chemistry, 10 . [Link] [DOI]
2019 Brannigan, R.P.; Kimmins, S.D.; Bobbi, E.; Caulfield, S.; Heise, A. (2019) 'Synthesis of Novel bis-Triazolinedione Crosslinked Amphiphilic Polypept(o)ide Nanostructures'. Macromolecular Chemistry and Physics, 220 . [Link] [DOI]
2018 Arno, MC; Brannigan, RP; Policastro, GM; Becker, ML; Dove, AP (2018) 'pH-Responsive, Functionalizable Spyrocyclic Polycarbonate: A Versatile Platform for Biocompatible Nanoparticles'. Biomacromolecules, 19 (8). [DOI]
2017 Brannigan, R.P.; Walder, A.; Dove, A.P. (2017) 'Application of Modified Amino Acid-Derived Diols as Chain Extenders in the Synthesis of Novel Thermoplastic Polyester-Urethane Elastomers'. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 5 . [Link] [DOI]
2016 Brannigan, RP; Khutoryanskiy, VV (2016) 'Synthesis and evaluation of mucoadhesive acryloyl-quaternized PDMAEMA nanogels for ocular drug delivery'. Colloids and surfaces. B, Biointerfaces, 155 . [DOI]
2016 Brannigan, R.P.; Walder, A.; Dove, A.P. (2016) 'Tunable Thermoplastic Poly(ester-urethane)s Based on Modified Serinol Extenders'. Macromolecules, 49 . [Link] [DOI]
2016 Brannigan, RP; Dove, AP (2016) 'Synthesis, properties and biomedical applications of hydrolytically degradable materials based on aliphatic polyesters and polycarbonates'. Biomaterials Science, 5 (1). [DOI]
2014 Brannigan, R.P.; Walder, A.; Dove, A.P. (2014) 'Block copolymer materials from the organocatalytic ring-opening polymerization of a pentaerythritol-derived cyclic carbonate'. Journal of Polymer Science, Part A: Polymer Chemistry, 52 . [Link] [DOI]
Certain data included herein are derived from the © Web of Science (2023) of Clarivate. All rights reserved.

Research Interests

Synthetic polymer chemistry, sustainable monomer and polymer design, biodegradable and bio-absorbable polymers, materials properties, polymers for biomedical, pharmaceutical and agricultural applications