High Throughput Screening

Our high-throughput screening core, called AUTOPILOT, is an automated analysis and cellular phenotyping platform. It is a breakthrough robotic facility which provides seamless end-to-end workflows in therapeutic and diagnostic research through automated liquid handling, nano volume acoustic transfer, flow cytometry and cell sorting, and high-content imaging with AI machine learning. These automated workflows can deliver comprehensive cell characterisation and profiles of phenotypic states in 2D and 3D systems.
 

The system comprises of the following components which are all integrated using a SCARA robot and housed in a specially designed Class II BSC enclosure:

  • Biomek i7 Liquid Handler
  • Echo 650 Acoustic Dispenser
  • SpectraMax i3x Plate Reader
  • CytoFLEX-SRT Cell Sorter
  • ImageXpress Confocal HT.ai
  • Amplius Solid Phase Extractor

 

Diagram of Autopilot